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Drug effects on learning and memory1

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Drug Discovery and Evaluation

1 F.1 Introduction

It is easily understood that behavioral psychopharmacologies faced with the task of dealing with extremely complex behavioral disturbances. This holds true for both patient groups: young people with learning and memory problems and elderly patients with memory deficits. For the elderly, difficulties arise in designing appropriate animal models of human aging or the deficits occurring during human aging. One of the major problems for experimental behavioral pharmacology is whether or not old animals are the appropriate models. At the first view it seems obvious that the study of potential geronto-psychopharmacologic drugs should be performed in old animals. However, the problem is much more complicated. Laboratory animals are not a homogenous population, especially when old. Most of these old animals who are one third survivors of a population have an individually different pathological history which is mostly unknown to the investigators. Some animals may be...

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Notes

  1. 1.

    1Contribution by E. Dere.

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Authors and Affiliations

  1. Johann Wolfgang Goethe-Universität, Frankfurt, Germany

    Prof. Dr. Dr. H. Gerhard Vogel

  2. Department of Pharmacology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, USA

    Prof. Dr. Wolfgang H. Vogel

  3. Aventis Deutschland GmbH, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt, Germany

    Prof. Dr. Bernward A. Schölkens & Prof. Dr. Jürgen Sandow

  4. Institut für Genetik, Avenfis Deutschland GmbH, Ludwig Maximilian-Universität München, München, Germany

    PD Dr. Günter Müller

  5. Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Canada

    Dr. Wolfgang F. Vogel (Assistant Professor)

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  1. Johann Wolfgang Goethe-Universität, Frankfurt, Germany

    H. Gerhard Vogel

  2. Department of Pharmacology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, USA

    Wolfgang H. Vogel

  3. Aventis Deutschland GmbH, Johann Wolfgang Goethe-Universität Frankfurt, Frankfurt, Germany

    Bernward A. Schölkens  & Jürgen Sandow  & 

  4. Institut für Genetik, Avenfis Deutschland GmbH, Ludwig Maximilian-Universität München, München, Germany

    Günter Müller

  5. Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Canada

    Wolfgang F. Vogel (Assistant Professor) (Assistant Professor)

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Vogel, H.G., Vogel, W.H., Schölkens, B.A., Sandow, J., Müller, G., Vogel, W.F. (2002). Drug effects on learning and memory1 . In: Vogel, H.G., Vogel, W.H., Schölkens, B.A., Sandow, J., Müller, G., Vogel, W.F. (eds) Drug Discovery and Evaluation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-29837-1_7

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