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Autoimmunhämolytische Anämien

  • Chapter
Pädiatrische Hämatologie und Onkologie

Zusammenfassung

Die autoimmunhämolytischen Anämien sind bei Kindern selten. Wenn sie auftreten, sind sie meistens durch eine akute und schwere Hämolyse gekennzeichnet. Wichtigster diagnostischer Test ist neben dem Blutbild der positive direkte Coombs-Test. Nach dem Reaktionsoptimum der Autoantikörper unterscheidet man Wärmeautoantikörper und Kälteautoantikörper. In der Regel sind die autoimmunhämolytischen Anämien sekundäre Erkrankungen, so dass nach primären Grunderkrankungen, besonders solchen aus dem Formenkreis der Autoimmunerkrankungen und nach Immundefekten, gesucht werden muß. Auch im Rahmen von Infektionen können sie auftreten. Medikamentös induzierte Formen sind bei Kindern selten. Für eine adäquate Behandlung ist eine enge Zusammenarbeit zwischen Klinik und Transfusionsmedizin erforderlich, zumal sich die Transfusionstherapie, vor allem im Initialstadium, schwierig gestalten kann.

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Author information

Authors and Affiliations

  1. Institut für Transfusionsmedizin, ChariTé Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin

    Prof. Dr. Abdulgabar Salama & Prof. Dr. Gerhard Gaedicke

Authors
  1. Prof. Dr. Abdulgabar Salama
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  2. Prof. Dr. Gerhard Gaedicke
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Editor information

Editors and Affiliations

  1. Forschungsinstitut für krebskranke Kinder, St. Anna Kinderspital, Kinderspitalgasse 6, 1090, Wien, Österreich

    Helmut Gadner

  2. Klinik für Allgemeine Pädiatrie und Knochenmarktransplantation, Charité Campus Virchow-Klinikum Otto-Heubner-Centrum für Kinder- und Jugendmedizin, Augustenburger Platz 1, 13353, Berlin

    Gerhard Gaedicke

  3. Zentrum für Kinderheilkunde und Jugendmedizin, Universitätsklinikum Freiburg, Mathildenstr. 1, 79106, Freiburg

    Charlotte Niemeyer

  4. Klinik und Poliklinik für Kinder- und Jugendmedizin, Universitätsklinikum Münster, Albert-Schweitzer-Str. 33, 48129, Münster

    Jörg Ritter

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Salama, A., Gaedicke, G. (2006). Autoimmunhämolytische Anämien. In: Gadner, H., Gaedicke, G., Niemeyer, C., Ritter, J. (eds) Pädiatrische Hämatologie und Onkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-29036-2_11

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  • DOI: https://doi.org/10.1007/3-540-29036-2_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-03702-6

  • Online ISBN: 978-3-540-29036-0

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