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Functional Magnetic Resonance Imaging of the Human Visual System

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Imaging of Orbital and Visual Pathway Pathology

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References

  • Aguirre GK, D’Esposito M (1997) Environmental knowledge is subserved by separable dorsal/ventral neural areas. J Neurosci 17:2512–2518

    PubMed  CAS  Google Scholar 

  • Aguirre GK, Zarahn E, D’Esposito M (1998) Neural components of topographical representation. Proc Natl Acad Sci USA 95:839–846

    Article  PubMed  CAS  Google Scholar 

  • Aine CJ (1995) A conceptual overview and critique of functional neuroimaging techniques in humans. I. MRI/fMRI and PET. Crit Rev Neurobiol 9:229–309

    PubMed  CAS  Google Scholar 

  • Bandettini PA, Wong EC, Kinks RS et al (1992) Time course EPI of human brain function during task activation. Magn Reson Med 25:390–397

    PubMed  CAS  Google Scholar 

  • Bandettini PA, Jesmanowicz A, Wong EC et al (1993) Processing strategies of time-course data sets in functional MRI on the human brain. Magn Reson Med 30:161–173

    PubMed  CAS  Google Scholar 

  • Bandettini PA, Kwong KK, Davis TL et al (1997) Characterization of cerebral blood oxygenation and flow changes during prolonged brain activation. Hum Brain Mapping 5:93–109

    Article  CAS  Google Scholar 

  • Basele HA, Morland AB, Wandell BA (1999) Topographic organization of human visual areas in the absence of input from primary cortex. J Neurosci 19:2619–2627

    Google Scholar 

  • Binder JR, Rao SM (1994) Human brain mapping with functional magnetic resonance imaging. In: Kertesz A (ed) Localization and neuroimaging in neuropsychology. Academic, San Diego, pp 185–212

    Google Scholar 

  • Bittar RG, Ptito A, Faubert J, Dumoulin SO, Ptito A (1999) Activation of the remaining hemisphere following stimulation of the blind hemifield in hemispherectomized subjects. Neuroimage 10:339–346

    Article  PubMed  CAS  Google Scholar 

  • Bittar RG, Ptito A, Dumoulin SO, Andermann F, Reutens DC (2000) Reorganization of the visual cortex in callosal agenesis and colpocephaly. J Clin Neurosci 7:13–15

    Article  PubMed  CAS  Google Scholar 

  • Blamire AM, Ogawa S, Ugurbil K et al (1992) Dynamic mapping of the human visual cortex by high-speed magnetic resonance imaging. Proc Natl Acad Sci USA 89:11069–11073

    Article  PubMed  CAS  Google Scholar 

  • Boynton GM, Engel SA, Glover GH et al (1996) Linear systems analysis of functional magnetic resonance imaging in human V1. J Neurosci 16:4207–4221

    PubMed  CAS  Google Scholar 

  • Brandt T, Bucher SF, Seelos KC, Dietrich M (1998) Bilateral functional MRI activation of the basal ganglia and middle temporal/medial superior temporal motion-sensitive areas: optokinetic stimulation in homonymous hemianopia. Arch Neurol 55:1126–1131

    Article  PubMed  CAS  Google Scholar 

  • Buckner RL (1998) fMRI data analysis. Syllabus of the 4th international conference on functional mapping of the human brain (brain mapping course), pp 82–92

    Google Scholar 

  • Buckner RL, Bandettini PA, O’Craven KM et al (1996) Detection of cortical activation during averaged single trials of cognitive task using functional magnetic resonance imaging. Proc Natl Acad Sci USA 93:14878–14883

    Article  PubMed  CAS  Google Scholar 

  • Buckner RL, Goodman J, Burock et al (1998) Functional-anatomic correlates of object priming in humans revealed by rapid presentation event-related fMRI. Neuron 20:285–296

    Article  PubMed  CAS  Google Scholar 

  • Chen W, Ugurbil K (1999) High spatial resolution functional magnetic resonance imaging at very-high-magnetic field. Top Magn Reson Imaging 10:63–78

    PubMed  CAS  Google Scholar 

  • Cohen MS, Kosslyn SM, Breiter HC et al (1996) Changes in cortical activity during mental rotation: a mapping study using functional MRI. Brain 119:89–100

    PubMed  Google Scholar 

  • Cohen JD, Perlstein WM, Braver TS et al (1997) Temporal dynamics of brain activation during a working memory task. Nature 386:604–608

    Article  PubMed  CAS  Google Scholar 

  • Corbetta M (1998) Frontoparietal cortical networks for directing attention and the eye to visual locations: identical, independent, or overlapping neural systems. Proc Natl Acad Sci USA 95:831–838

    Article  PubMed  CAS  Google Scholar 

  • Courtney SM, Ungerleider LG (1997) What fMRI has taught us about human vision. Curr Opin Neurobiol 7:554–561

    Article  PubMed  CAS  Google Scholar 

  • Courtney SM, Ungerleider LG, Keil K et al (1997) Transient and sustained activity in a distributed neural system for human working memory. Nature 386:608–611

    Article  PubMed  CAS  Google Scholar 

  • Dale AM, Buckner RL (1997) Selective averaging of rapidly presented individual trials using fMRI. Hum Brain Mapping 5:329–340

    Article  Google Scholar 

  • Damasio H, Frank RJ (1992) Three-dimensional in vivo mapping of brain lesions in humans. Arch Neurol 49:137–143

    PubMed  CAS  Google Scholar 

  • DeYoe EA, Bandettini P, Neitz J et al (1994) Functional magnetic resonance imaging (FMRI) of the human brain. J Neurosci Methods 54:171–187

    Article  PubMed  CAS  Google Scholar 

  • DeYoe EA, Carman GJ, Bandettini P et al (1996) Mapping striate and extrastriate visual areas in human cerebral cortex Proc Natl Acad Sci USA 93:2382–2386

    Article  PubMed  CAS  Google Scholar 

  • Duong TQ, Kim DS, Ugurbil K, Kim SG (2000) Spatiotemporal dynamics of the BOLD fMRI signals: towards mapping submillimeter cortical columns using the early negative response. Magn Reson Med 44:231–242

    Article  PubMed  CAS  Google Scholar 

  • Edelman RP, Siewert B, Daeby DG et al (1994) Qualitative mapping of cerebral blood flow and functional localization with echo-planar MR imaging and signal targeting with alternating radio frequency. Radiology 192:513–520

    PubMed  CAS  Google Scholar 

  • Eden GF, VanMeter JW, Rumsey JM et al (1996) Abnormal processing of visual motion in dyslexia revealed by functional brain imaging. Nature 382:66–69

    Article  PubMed  CAS  Google Scholar 

  • Engel SA, Rumelhart DE, Wandell BA et al (1994) MRI of human visual cortex. Nature 369:525

    Article  PubMed  CAS  Google Scholar 

  • Engel SA, Glover GH, Wandell BA (1997) Retinotopic organization in human visual cortex and the spatial precision of functional MRI. Cereb Cortex 7:181–192

    Article  PubMed  CAS  Google Scholar 

  • Ernst T, Hennig J (1994) Observation of a fast response in functional MR. Magn Reson Med 32:146–149

    PubMed  CAS  Google Scholar 

  • Farah MJ (1990) Visual agnosia. MIT Press, Cambridge, MA

    Google Scholar 

  • Felleman DJ, Van Essen DC (1991) Distributed hierarchical processing in the primate cerebral cortex. Cereb Cortex 1:1–47

    PubMed  CAS  Google Scholar 

  • Ffytche DH, Howard RJ, Brammer MJ, David A, Woodruff P, Williams S (1998) The anatomy of conscious vision: and fMRI study of visual hallucinations. Nat Neurosci 1:738–742

    Article  PubMed  CAS  Google Scholar 

  • Fox PT, Raichle ME (1986) Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. Proc Natl Acad Sci USA 83:1140–1144

    Article  PubMed  CAS  Google Scholar 

  • Frahm J, Kruger G, Merdoldt KD et al (1996) Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal activation in man. Magn Reson Med 35:143–148

    PubMed  CAS  Google Scholar 

  • Friston KJ, Josephs O, Rees G, et al (1997) Nonlinear event-related responses in fMRI. Magn Reson Med 39:41–52

    Google Scholar 

  • Friston KJ, Fletcher P, Josephs O et al (1998) Event-related fMRI: characterizing differential responses. Neuroimage 7:30–40

    Article  PubMed  CAS  Google Scholar 

  • Gareau PJ, Gati JS, Menon RS et al (1999) Reduced visual evoked responses in multiple sclerosis patients with optic neuritis: comparison of functional magnetic resonance imaging and visual evoked potentials. Mult Scler 5:161–164

    Article  PubMed  CAS  Google Scholar 

  • Golay X, Kollias SS, Stoll G et al (1998) A new correlation-based fuzzy logic clustering algorithm for fMRI. Magn Reson Med 40:249–260

    PubMed  CAS  Google Scholar 

  • Grabowski TJ, Damasio AR (1996) Improving functional imaging techniques: the dream of a single image for a single mental event (commentary). Proc Natl Acad Sci USA 93:14302–14303

    Article  PubMed  CAS  Google Scholar 

  • Hathout GM, Kirlew KA, So GJK et al (1994) MR imaging signal response to sustained stimulation in human visual cortex. JMRI 4:537–543

    PubMed  CAS  Google Scholar 

  • Hedera P, Lai S, Haake EM et al (1994) Abnormal connectivity of the visual pathways in human albinos demonstrated by susceptibility-sensitized MRI. Neurology 44:1921–1926

    PubMed  CAS  Google Scholar 

  • Hirsch J, DeLaPaz RL, Relkin NR et al (1995) Illusory contours activate specific regions in human visual cortex: evidence from functional magnetic resonance imaging. Proc Natl Acad Sci USA 92:6469–6473

    Article  PubMed  CAS  Google Scholar 

  • Horton JC, Hoyt WF (1991) The representation of the visual field in the human striate cortex: a revision of the classic Holmes map. Arch Ophthalmol 109:816–824

    PubMed  CAS  Google Scholar 

  • Howard RJ, Brammer M, Wright I et al (1996) A direct demonstration of functional specialization within motion-related visual area and auditory cortex of the human brain. Curr Biol 6:1015–1019

    Article  PubMed  CAS  Google Scholar 

  • Hu X, Le TH, Ugurbil K (1997) Evaluation of the early response in fMRI in individual subjects using short stimulus duration. Magn Reson Med 37:877–884

    PubMed  CAS  Google Scholar 

  • Kanwisher N, McDermott J, Chun MM (1997) The fusiform face area: a module in human extrastriate cortex specialized for the perception of faces. J Neurosci 17:4302–4311

    PubMed  CAS  Google Scholar 

  • Kass JH (1995) Progress and puzzles. Curr Biol 5:1126–1128

    Article  Google Scholar 

  • Kim SG, Tsekos NV (1997) Perfusion imaging by a flow-sensitive alternating inversion recovery (FAIR) technique: application to functional brain imaging. Magn Reson Med 37:425–435

    PubMed  CAS  Google Scholar 

  • Kim SG, Ashe J, Hendrich K, Ellermann JM, Merkle H, Ugurbil K, Georgopoulos AP (1993) Functional magnetic resonance imaging of motor cortex: hemispheric asymmetry and handedness. Science 261:615–617

    PubMed  CAS  Google Scholar 

  • Kleinschmidt A, Lee BB, Requardt M et al (1996) Functional mapping of color processing by magnetic resonance imaging of responses to selective P-and M-pathway stimulation. Exp Brain Res 110:279–288

    Article  PubMed  CAS  Google Scholar 

  • Kollias SS, Golay X, Valavanis A (1996a) Localization of regional brain activity using functional magnetic resonance imaging: preliminary applications in neurosurgical patients. Crit Rev Neurosurg 6:159–177

    Google Scholar 

  • Kollias SS, Valavanis A, Golay XG et al (1996b) Functional magnetic resonance imaging of cortical activation. Int J Neuroradiol 2:450–472

    Google Scholar 

  • Kollias SS, Bernays R, Marugg R, Romanowski B, Yonekawa Y, Valavanis A (1998a) Target definition and trajectory optimization for interactive MR-guided biopsies of brain tumors in an open-configuration MRI system. J Magn Reson Imaging (JMRI) 8:143–159

    CAS  Google Scholar 

  • Kollias SS, Landau K, Khan N et al (1998b) Functional evaluation of the visual cortex in patients with retrochiasmatic lesions using magnetic resonance imaging. J Neurosurg 89:780–790

    PubMed  CAS  Google Scholar 

  • Kollias SS, Golay X, Boesiger P, Valavanis A (2000) Dynamic characteristics of oxygenation-sensitive MR signal during application of varying temporal protocols for imaging of human brain activity. Neuroradiology 42:591–601

    Article  PubMed  CAS  Google Scholar 

  • Kwong KK (1995) Functional magnetic resonance imaging with echo planar imaging. Magn Reson Med 11:1–20

    CAS  Google Scholar 

  • Kwong KK, Belliveau JW, Chesler DA et al (1992) Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci USA 89:5675–5679

    Article  PubMed  CAS  Google Scholar 

  • Kwong KK, Chesler DA, Weisskoff RM et al (1995) MR perfusion studies with T1-weighted echo planar imaging. Magn Reson Med 34:878–887

    PubMed  CAS  Google Scholar 

  • Lai S, Hopkins AL, Haacke EM et al (1993) Identification of vascular structures as a major source of signal contrast in high resolution 2D and 3D functional activation imaging of the motor cortex at 1.5 T: preliminary results. Magn Reson Med 30:387–392

    PubMed  CAS  Google Scholar 

  • LeBihan D, Turner R, Zeffiro TA et al (1993) Activation of human primary visual cortex during visual recall: a magnetic resonance imaging study. Proc Natl Acad Sci USA 90:11802–11805

    Article  CAS  Google Scholar 

  • Malach R, Reppas JB, Benson RR et al (1995) Object-related activity revealed by functional magnetic resonance imaging in human occipital cortex. Proc Natl Acad Sci USA 92:8135–8139

    Article  PubMed  CAS  Google Scholar 

  • Malonek D, Grinvald A (1996) Interactions between electrical activity and cortical microcirculation revealed by imaging spectroscopy: implications for functional brain mapping. Science 272:551–554

    PubMed  CAS  Google Scholar 

  • Masuoka LK, Anderson AW, Gore JC, McCarthy G, Spencer DD, Novotny EJ (2000) Functional magnetic resonance imaging identifies abnormal visual cortical function in patients with occipital lobe epilepsy. Epilepsia 40:1248–1253

    Article  Google Scholar 

  • McKeown MJ, Jung T-P, Makeig S et al (1998) Spatially independent activity patterns in functional MRI data during the stroop color-naming task. Proc Natl Acad Sci USA 95:803–810

    Article  PubMed  CAS  Google Scholar 

  • Menon RS, Ogawa S, Strupp JP et al (1995a) BOLD based functional MRI at 4 Tesla includes a capillary bed contribution: echo-planar imaging correlates with previous optical imaging using intrinsic signals. Magn Reson Med 33:453–459

    PubMed  CAS  Google Scholar 

  • Menon RS, Ogawa S, Ugurbil K (1995b) High-temporal-resolution studies of the human primary visual cortex at 4 T: teasing out the oxygenation contribution in FMRI. Int J Imaging Systems Technol 6:209–215

    Google Scholar 

  • Menon RS, Ogawa S, Strupp JP et al (1997) Ocular dominance in human V1 demonstrated by functional magnetic resonance imaging. J Neurphysiol 77:2780–2787

    CAS  Google Scholar 

  • Miki A, Nakajima T, Fujita M et al (1996a) Functional magnetic resonance imaging in homonymous hemianopsia. Am J Ophthalmol 121:258–266

    PubMed  CAS  Google Scholar 

  • Miki A, Nakajima T, Takagi M et al (1996b) Detection of visual dysfunction in optic atrophy by functional magnetic resonance imaging during monocular visual stimulation. Am J Ophthalmol 122:404–415

    PubMed  CAS  Google Scholar 

  • Moseley EM, Glover HG (1995) Functional MR imaging: capabilities and limitations. Neuroimaging Clin North Am 5:161–191

    CAS  Google Scholar 

  • Muckli L, Tonhausen N, Goebel R et al (1998). Reduced fMRI response to monocular amblyopic eye stimulation in extrastriate visual areas. Proceedings of the 4th international conference on functional mapping of the human brain, p 19

    Google Scholar 

  • Nakamura K, Honda M, Okada T, Hankawa T, Fukuyama H, Konishi J, Shibasaki H (2000) Attentional modulation of parieto-occipital cortical responses: implications for hemispatial neglect. J Neurol Sci 176:136–143

    Article  PubMed  CAS  Google Scholar 

  • Newcombe F, Ratcliff G. (1989). Disorders of visuospatial analysis. In: Boller F, Grafman J (eds) Handbook of neuropsychology. Elsevier, Amsterdam, pp 333–356

    Google Scholar 

  • Ogawa S, Lee TM, Kay AR, Tank DW (1990) Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci USA 87:9868–9872

    Article  PubMed  CAS  Google Scholar 

  • Pauling L, Coryell CD (1936) The magnetic properties and structure of hemoglobin, oxyhemoglobin, and carbonmonoxyhemoglobin. Proc Natl Acad Sci USA 22:210–216

    Article  PubMed  CAS  Google Scholar 

  • Polk TA, Farah MJ (1998) The neural development and organization of letter recognition: evidence from functional neuroimaging, computational modeling, and behavioral studies. Proc Natl Acad Sci USA 95:847–852

    Article  PubMed  CAS  Google Scholar 

  • Puce A, Allison T, Asgari M et al (1996) Differential sensitivity of human visual cortex to faces, letterstrings, and textures: a functional magnetic resonance imaging study. J Neurosci 16:1192–5215

    Google Scholar 

  • Raichle ME (1998) Behind the scenes of functional brain imaging: a historical and physiological perspective. Proc Natl Acad Sci USA 95:765–772

    Article  PubMed  CAS  Google Scholar 

  • Reshaw PF, Yurgelun-Todd DA, Cohen BM (1994) Greater hemodynamic response to photic stimulation in schizophrenic patients: an echo planar MRI study. Am J Psychiatry 151:1493–1495

    Google Scholar 

  • Rizzo M, Nawrot M (1993) Human visual cortex and its disorders. Curr Opin Ophthalmol 4:38–47

    Article  Google Scholar 

  • Rosen BR, Buckner RL, Dale AM (1998) Event-related functional MRI: past, present, and future. Proc Natl Acad Sci 95:773–780

    Article  PubMed  CAS  Google Scholar 

  • Sakai K, Watanabe E, Onodera Y et al (1995) Functional mapping of the human colour centre with echo-planar magnetic resonance imaging. Proc R Soc Lond [Biol] 261:89–98

    CAS  Google Scholar 

  • Savoy RL, Bandettini PA, O’Kraven KM et al (1995) Pushing the temporal resolution of fMRI: studies of very brief visual stimuli onset variability and asynchrony, and stimulus-correlated changes in noise. Proceedings of the ISMRM 3rd annual meeting Nice, France, p 450

    Google Scholar 

  • Schneider W, Noll DC, Cohen JD (1993) Functional topographic mapping of the cortical ribbon in human vision with conventional MR scanners. Nature 365:150–153

    Article  PubMed  CAS  Google Scholar 

  • Sereno MI, Dale AM, Reppas JB et al (1995) Borders of multiple visual areas in humans revealed by functional magnetic resonance imaging Science 268:889–893

    CAS  Google Scholar 

  • Tootell RBH, Reppas JB, Dale AM et al (1995) Visual motion aftereffect in human cortical area MT revealed by functional magnetic resonance imaging. Nature 375:139–141

    Article  PubMed  CAS  Google Scholar 

  • Tootell RBH, Dale AM, Sereno MI et al (1996) New images form human visual cortex. Trends Neurosci 19:481–498

    Article  PubMed  CAS  Google Scholar 

  • Tootell RB, Hadjikhani NK, Vanduffel W et al (1998a) Functional analysis of primary visual cortex in humans. Proc Natl Acad Sci USA 95:811–817

    Article  PubMed  CAS  Google Scholar 

  • Tootell RB, Mendola JD, Hadjikhani NK et al (1998b) The representation of the ipsilateral visual field in human cerebral cortex. Proc Natl Acad Sci 95:818–824

    Article  PubMed  CAS  Google Scholar 

  • Ugurbil K, Hu X, Chen W, Zhu XH, Kim SG, Georgopoulos A (1999) Functional mapping in the human brain using high magnetic fields. Philos Trans R Soc Lond B Biol Sci 354:1195–1213

    Article  PubMed  CAS  Google Scholar 

  • Ungerleider LG, Haxby JV (1994) “What” and “where” in the human brain. Curr Opin Biol 4:157–165

    CAS  Google Scholar 

  • Ungerleider LG, Courtney SM, Haxby JV (1998) A neural system for human visual working memory. Proc Natl Acad Sci USA 95:883–890

    Article  PubMed  CAS  Google Scholar 

  • Van Essen DC, Drury HA, Joshi S et al (1998) Functional and structural mapping of human cerebral cortex: solutions are in the surfaces. Proc Natl Acad Sci USA 95:788–795

    Article  PubMed  Google Scholar 

  • Van Zijl PCM, Eleff SM, Ulatowski JA et al (1998) Quantitative assessment of blood flow, blood volume and blood oxygenation effcts in functional magnetic resonance imaging. Nat Med 4:159–167

    Article  PubMed  Google Scholar 

  • Zarahn E, Aguirre GK, D’Esposito M (1997) Empirical analyses of BOLD fMRI statistics. I. Spatially unsmoothed data collected under null-hypothesis conditions. Neuroimage 5:179–197

    Article  PubMed  CAS  Google Scholar 

  • Zeki S (1992) The visual image in mind and brain. Scientific American 267:69–76

    Article  Google Scholar 

  • Zeki S, Watson JPG, Lueck CJ et al (1991) A direct demonstration of functional specialization in human visual cortex. J Neurosci 11:641–649

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Institute of Neuroradiology, University Hospital of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland

    PD Spyros S. Kollias MD

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  1. PD Spyros S. Kollias MD
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Editors and Affiliations

  1. Leuven, Germany

    A. L. Baert

  2. Heidelberg, Germany

    K. Sartor

  3. Institute of Neuroradiology, Medical School University of Mainz, Langenbeckstrasse 1, 55101, Mainz, Germany

    Wibke S. Müller-Forell MD

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Kollias, S.S. (2006). Functional Magnetic Resonance Imaging of the Human Visual System. In: Baert, A.L., Sartor, K., Müller-Forell, W.S. (eds) Imaging of Orbital and Visual Pathway Pathology. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27989-X_4

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