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Combinatorial Method for Surface-Confined Sensor Design and Fabrication

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Frontiers in Chemical Sensors

Part of the book series: Springer Series on Chemical Sensors and Biosensors ((SSSENSORS,volume 3))

Abstract

The procedure for the combinatorial fabrication of new sensing materials for cations and anions based on self-assembled monolayers (SAM) is discussed. A library of different sensitive substrates is generated by sequential deposition of fluorophores and small ligand molecules onto an amino-terminated SAM coated glass. The preorganization provided by the surface avoids the need for complex receptor design, allowing for a combinatorial approach to sensing systems based on individually deposited small molecules. Additionally the sensing system has been miniaturized to the microscale using microcontact printing and integrating the sensory SAMs on the walls of microchannels.

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Authors and Affiliations

  1. Department of Supramolecular Chemistry and Technology, MESA+ Institute for Nanotechnology and Faculty of Science and Technology, University of Twente, P.O. Box 217, 7500 AE, Enschede, The Netherlands

    Lourdes Basabe-Desmonts, Rebecca S. Zimmerman, David N. Reinhoudt & Mercedes Crego-Calama

Authors
  1. Lourdes Basabe-Desmonts
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  2. Rebecca S. Zimmerman
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  3. David N. Reinhoudt
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  4. Mercedes Crego-Calama
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Editor information

Editors and Affiliations

  1. Lab. of Applied Photochemistry, Universidad Complutense, 28040, Madrid, Spain

    Guillermo Orellana

  2. Dept. of Analytical Chemistry, Universidad Complutense, 28040, Madrid, Spain

    Maria C. Moreno-Bondi

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© 2005 Springer-Verlag Berlin Heidelberg

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Basabe-Desmonts, L., Zimmerman, R.S., Reinhoudt, D.N., Crego-Calama, M. (2005). Combinatorial Method for Surface-Confined Sensor Design and Fabrication. In: Orellana, G., Moreno-Bondi, M.C. (eds) Frontiers in Chemical Sensors. Springer Series on Chemical Sensors and Biosensors, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27757-9_5

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