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Towards Probabilistic Model Checking on P Systems Using PRISM

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Membrane Computing (WMC 2006)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 4361))

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Abstract

This paper presents the use of P systems and π-calculus to model interacting molecular entities and how they are translated into a probabilistic and symbolic model checker called PRISM.

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References

  1. Alur, R., Henzinger, T.A.: Reactive Modules. Formal Methods in System Design 15, 7–48 (1999)

    Article  Google Scholar 

  2. Andrei, O., Ciobanu, G., Lucanu, D.: Executable Specifications of P Systems. In: Mauri, G., Păun, G., Jesús Pérez-Jímenez, M., Rozenberg, G., Salomaa, A. (eds.) WMC 2004. LNCS, vol. 3365, pp. 126–145. Springer, Heidelberg (2005)

    Chapter  Google Scholar 

  3. Bernardini, F., Manca, V.: P Systems with Boundary Rules. In: Păun, G., Rozenberg, G., Salomaa, A., Zandron, C. (eds.) WMC 2002. LNCS, vol. 2597, pp. 107–118. Springer, Heidelberg (2003)

    Chapter  Google Scholar 

  4. Bernardini, F., Gheorghe, M.: Population P Systems. J. UCS 10(5), 509–539 (2004)

    MathSciNet  Google Scholar 

  5. Bianco, L., Fontana, F., Manca, V.: P Systems with Reaction Maps. International Journal of Foundations of Computer Science 17(1), 27–48 (2006)

    Article  MATH  MathSciNet  Google Scholar 

  6. Calder, M., Vyshemirsky, V., Gilbert, D., Orton, R.: Analysis of Signalling Pathways using Continuous Time Markov Chains. Transactions on Computational Systems Biology (to appear)

    Google Scholar 

  7. Dang, Z., Ibarra, O.H.: On One-Membrane P systems Operating in Sequential Mode. Int. J. Found. Comput. Sci. 16(5), 867–881 (2005)

    Article  MATH  MathSciNet  Google Scholar 

  8. Fontana, F., Bianco, L., Manca, V.: P Systems and the Modeling of Biochemical Oscillations. In: Freund, R., Păun, G., Rozenberg, G., Salomaa, A. (eds.) WMC 2005. LNCS, vol. 3850, pp. 199–208. Springer, Heidelberg (2006)

    Chapter  Google Scholar 

  9. Gillespie, D.T.: A General Method for Numerically Simulating the Stochastic Time Evolution of Coupled Chemical Reactions. J. Comput Physics 22, 403–434 (1976)

    Article  MathSciNet  Google Scholar 

  10. Gillespie, D.T.: Exact Stochastic Simulation of Coupled Chemical Reactions. The Journal of Physical Chemistry 81(25), 2340–2361 (1977)

    Article  Google Scholar 

  11. Goss, P.J.E., Peccoud, J.: Quantitative modeling of stochastic systems in molecular biology using stochastic Petri nets. Proc. Natl. Acad. Sci. USA 95, 6750–6755 (1998)

    Article  Google Scholar 

  12. Krasnogor, N., Gheorghe, M., Terrazas, G., Diggle, S., Williams, P., Camara, M.: An appealling Computational Mechanism Drawn from Bacterial Quorum Sensing. Bulletin of the EATCS 85, 135–148 (2005)

    MATH  MathSciNet  Google Scholar 

  13. Lecca, P., Corrado, P.: Cell Cycle Control in Eukaryotes: A BioSpi Model. Electronic Notes in Theoretical Computer Science (to appear)

    Google Scholar 

  14. Novak, B., Csikasz-Nagy, A., Gyorffy, B., Nasmyth, K., Tyson, J.J.: Model Scenarios for Evolution of the Eukaryotic Cell Cycle. Phil. Trans. R. Soc. Lond. 353, 2063–2076 (1998)

    Article  Google Scholar 

  15. Păun, G.: Computing with Membranes. Journal of Computer and System Sciences 61(1), 108–143 (2000)

    Article  MATH  MathSciNet  Google Scholar 

  16. Pérez-Jiménez, M.J., Romero-Campero, F.J.: Modelling Gene Expression Control Using P Systems: The Lac Operon, A Case Study (submitted)

    Google Scholar 

  17. Pérez-Jiménez, M.J., Romero-Campero, F.J.: P Systems, a New Computational Modelling Tool for Systems Biology. In: Priami, C., Plotkin, G. (eds.) Transactions on Computational Systems Biology VI. LNCS (LNBI), vol. 4220, pp. 176–197. Springer, Heidelberg (2006)

    Chapter  Google Scholar 

  18. Pérez-Jiménez, M.J., Romero-Campero, F.J.: A Model of the Quorum Sensing System in Vibrio Fischeri Using P Systems (submitted)

    Google Scholar 

  19. Pescini, D., Besozzi, D., Mauri, G., Zandron, C.: Dynamical Probabilistic P Systems. International Journal of Foundations of Computer Science 17(1), 183–195 (2006)

    Article  MATH  MathSciNet  Google Scholar 

  20. Regev, A., Shapiro, E.: The π-Calculus as an Abstraction for Biomolecular Systems. In: Ciobanu, G., Rozenberg, G. (eds.) Modelling in Molecular Biology. Springer, Berlin (2004)

    Google Scholar 

  21. Terrazas, G., Krasnogor, N., Gheorghe, M., Bernardini, F., Diggle, S., Cámara, M.: An Environment Aware P-System Model of Quorum Sensing. In: Cooper, S.B., Löwe, B., Torenvliet, L. (eds.) CiE 2005. LNCS, vol. 3526, pp. 479–485. Springer, Heidelberg (2005)

    Chapter  Google Scholar 

  22. PRISM Web Site: http://www.cs.bham.ac.uk/~dxp/prism/

  23. The P Systems Web Site: http://psystems.disco.unimib.it

  24. SciLab Web Site: http://scilabsoft.inria.fr/

  25. P System Simulator: http://www.dcs.shef.ac.uk/~marian/PSimulatorWeb/PSystemMF.htm

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© 2006 Springer-Verlag Berlin Heidelberg

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Romero-Campero, F.J., Gheorghe, M., Bianco, L., Pescini, D., Pérez-Jiménez, M.J., Ceterchi, R. (2006). Towards Probabilistic Model Checking on P Systems Using PRISM. In: Hoogeboom, H.J., Păun, G., Rozenberg, G., Salomaa, A. (eds) Membrane Computing. WMC 2006. Lecture Notes in Computer Science, vol 4361. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11963516_30

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  • DOI: https://doi.org/10.1007/11963516_30

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69088-7

  • Online ISBN: 978-3-540-69090-0

  • eBook Packages: Computer ScienceComputer Science (R0)

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