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Abstract

Arthritis has afflicted man from prehistoric times and has accompanied him throughout his evolutionary history. However, rheumatology – the discipline of medicine dealing with disorders of joint and connective tissues – is perhaps the youngest of medical specialties. Our understanding of various types of arthritis has improved considerably leading to evolution of specific and effective therapies for most types of arthritis especially in the last few decades. Despite these advancements many myths and ignorance is still prevalent with respect to arthritis. The present write up is aimed to improve our understanding

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References

  • ACR Subcommittee on Rheumatoid Arthritis Guidelines. (2002) Guidelines for the management of Rheumatoid Arthritis. Arthritis Rheum, 46: No 2; 328–346.

    Google Scholar 

  • Black, C.M., Halkier, S.L., et al. (1998) Oral iloprost in Raynaud’s phenomenon secondary to systemic sclerosis- A multicentre, placebo-controlled dose comparison study. Br J Rheum, 37: 952–60.

    Article  CAS  Google Scholar 

  • Boers Met, et al. (1997) COBRA trial. Lancet, 350: 309–318.

    Article  PubMed  CAS  Google Scholar 

  • Ceru, S., Pancreas, P., et al. (1997) Effects of five-day versus one-day infusion of iloprost on the peripheral microcirculation in patients with systemic sclerosis. Clin Exp Rheum, 15: 381–5.

    CAS  Google Scholar 

  • Clements, P.J., Wong, W.K., Seibold, J.R., et al. (1997) High dose versus low-dose penicillamine in early diffuse systemic sclerosis: analysis of trial. Arthritis Rheum, 40: S354.

    Google Scholar 

  • Daniel, O., Clegg, M.D., Domenic, J., Reda, Ph.D., Crystal, L., Harris, et al. (2006) Glucosamine, Chondroitin Sulfate, and the Two in Combination for Painful Knee Osteoarthritis (GAIT). NEJM 354, 795–808.

    Article  Google Scholar 

  • Darcy, S., Majka and Michael Holers V. (2003) Can We Accurately Predict the Development of Rheumatoid Arthritis in the Preclinical Phase? Arthritis Rheum, 48: 2701.

    Article  Google Scholar 

  • Esmeralda, T.H., Molenaar, Alexandre, E., Voskuyl, Huib, J., Dinant, P., Dick Bezemer, Maarten Boers and Ben, A.C. Dijkmans. (2004) Progression of Radiologic Damage in Patients With Rheumatoid Arthritis in Clinical Remission. Arthritis Rheum, 50: 36–42.

    Article  Google Scholar 

  • Is Remission the Mission in RA? (2005) New Information from the 2005 EULAR Conference. www.medscape.com/viewarticle/508075_10. Last accessed on 8th March, 2006.

    Google Scholar 

  • Lard, L.R., Visser, H., Speyer, I., et al. (2001) Early versus delayed treatment in patients with recent onset rheumatoid arthritis: comparison of two cohorts who received different treatment strategies. Am J Med, 111: 446–451.

    Article  PubMed  CAS  Google Scholar 

  • Lisukov, I.A., Sizikova, S.A., Kulagin, A.D., et al. (2004) High-dose immunosuppression with autologous stem cell transplantation in severe refractory systemic lupus erythematosus. Lupus 13:89–94. This series of six SLE patients treated with stem cell transplantation suggests that long-term, steroid-free remissions are possible, but early mortality is not uncommon.

    Article  PubMed  CAS  Google Scholar 

  • Lorenz, H., Grunke, M., Wendler, J., et al. (2004) Effective treatment of active SLE-associated glomerulonephritis (GN) with 15-deoxyspergualin (15-DSG; gusperimus). Program and abstracts of the American College of Rheumatology/Association of Rheumatology Health Professionals 68th Annual Scientific Meeting; October 16–21; San Antonio, Texas. Abstract 1035.

    Google Scholar 

  • Marc, D.C. (2005) The Clinical Manifestations of Chronic Hyperuricemia: Focus on Gout. www.medscape.com/viewarticle/496670_12. Last accessed on 8th March, 2006.

    Google Scholar 

  • Mease, P.J. (2004) Psoriatic Arthritis Therapy. Curr Opin Rheumatol, 16.

    Google Scholar 

  • Mok, C.C., Tong, K.H., To, C.H., et al. (2004) Tacrolimus for the initial treatment of diffuse proliferative lupus glomerulonephritis: a comparative study with intravenous pulse cyclophosphamide. Program and abstracts of the American College of Rheumatology/Association of Rheumatology Health Professionals 68th Annual Scientific Meeting; October 16–21; San Antonio, Texas. Abstract 1128.

    Google Scholar 

  • Mottosen, T., et al. (1999) Finnish Rheumatoid Arthritis Combination Therapy trial. Lancet, 353: 1568–1573.

    Article  Google Scholar 

  • O’ Dell, J.R., Haire, C.E., Erickson, N., et al. (1996) Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and hydroxycholoroquine or combination of all three medications. N Engl J Med, 334: 1287–1291.

    Article  CAS  Google Scholar 

  • Paco, M.J., Welsing, Robert B.M., Landewé, Piet L.C.M., van Riel, Maarten Boers, Anke, M., van Gestel, Sjef van der Linden, Hilde, L., Swinkels and Dé sirée, M.F.M., van der Heijde. (2004) The Relationship Between Disease Activity and Radiologic Progression in Patients With Rheumatoid Arthritis: A Longitudinal Analysis. Arthritis Rheum, 50: 2082–2093.

    Article  Google Scholar 

  • Povelka, K., Gatterova, J., Olejarova, M., Machacek, S., Giacovelli, G. and Rovati, L.C. (2002) Glucosamine sulfate use and delay of progression of Knee osteoarthritis: a 3 year, randomised, placebo-controlled, double blind study. Arch Intern Med, 162: 2113–23.

    Article  Google Scholar 

  • Reginster, J., Deroisy, R., Rovati, Lee, R., Lejeune, E., Bruyere, O., et al. (2001). Long term effects of glucosamine sulfate on osteoarthritis progression. Lancet, 357: 252–6.

    Article  Google Scholar 

  • Reilly, P.A., Cosh, J.A., Maddison, P.J., et al. (1990) Mortality and survival in rheumatoid arthritis: a 25 year prospective study of 100 patients. Ann Rheum Dis, 49: 363–369.

    Article  PubMed  CAS  Google Scholar 

  • Saskia ten Wolde, Jo Hermans, Ferdinand, C. and Breedveld and Ben, A.C. Dijkmans. (1997) Effect of resumption of second line drugs in patients with rheumatoid arthritis that flared up after treatment discontinuation. Ann. Rheum. Dis. Apr, 56: 235–239.

    Article  Google Scholar 

  • Steen, V.D., Medsger, T.A. and Rodnan, G.P. (1984) D-Penicillamine therapy in progressive systemic sclerosis. Ann Intern Med, 97: 652–9.

    Google Scholar 

  • Thomson, G.T. (2000) Clinical efficacy of mesalamine in the treatment of spondyloarthroathy. J Rheumatol, 27: 714–8.

    PubMed  CAS  Google Scholar 

  • Traynor, A.E., Barr, W.G., Rosa, R.M., et al. (2002): Hematopoietic stem cell transplantation for severe and refractory lupus. Analysis after five years and fifteen patients. Arthritis Rheum 2002, 46: 2917–2923.

    Article  Google Scholar 

  • Williams, H.J., Ward, J.R., Reading, J.C., et al. (1992) Comparison of auranofin, methotrexate and combination of both in the treatment of rheumatoid arthritis. Arthritis Rheum, 35: 259–269.

    Article  PubMed  CAS  Google Scholar 

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Syngle, A. (2006). Arthritis and its Treatment. In: Rattan, S.I., Kassem, M. (eds) Prevention and Treatment of Age-related Diseases. Springer, Dordrecht. https://doi.org/10.1007/1-4020-5058-5_7

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