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Prenatal Betamethasone Exposure Suppresses Kindling Epileptogenesis in Immature Rats

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Kindling 6

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 55))

Abstract

Administration of corticosteroids is common in obstetrics. Corticosteroids are frequently used in pregnant women between 24–34 gestation weeks, if there is a danger of imminent delivery with subsequent respiratory distress syndrome of the newborn.1 In this situation, one course of corticosteroid therapy is applied, usually consisting of 2–4 injections of betamethasone or dexamethasone spread over 24–48 hours. Follow-up studies in humans have demonstrated that this therapy regimen significantly improves the chance of the premature newborn for survival with no long-term side effects.

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Author information

Authors and Affiliations

  1. Departments of Neurology and Neuroscience, Albert Einstein College of Medicine, Einstein/Montefiore Epilepsy Management Center, 1410 Pelham Parkway South, Bronx, NY, 10461, USA

    Libor Velíšek

Authors
  1. Libor Velíšek
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Editor information

Editors and Affiliations

  1. University of Saskatchewan, Saskatoon, Saskatchewan, Canada

    Michael E. Corcoran

  2. Albert Einstein College of Medicine, Yeshiva University, Bronx, New York, USA

    Solomon L. Moshé

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© 2005 Springer Science+Business Media, Inc.

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Velíšek, L. (2005). Prenatal Betamethasone Exposure Suppresses Kindling Epileptogenesis in Immature Rats. In: Corcoran, M.E., Moshé, S.L. (eds) Kindling 6. Advances in Behavioral Biology, vol 55. Springer, Boston, MA. https://doi.org/10.1007/0-387-26144-3_2

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