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In Vitro and In Vivo Effects of Taurine and Structurally Related Sulfur-Containing Compounds Against Phenylhydrazine-Induced Oxidative Damage to Erythrocytes

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Taurine 4

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References

  1. Alvarez, J.G., and Storey, N.T., 1983, Taurine, hypotaurine, epinephrine and albumin inhibit lipid peroxidation in rabbit spermatozoa and protect against loss of motility. Biol. Reprod. 29:548–555.

    Google Scholar 

  2. Arduini, A., Stem, A., Storto, S., Belfiglio, M., Mancinelli, G., Scurti, R., and Federici, G., 1989, Effect of oxidative stress on membrane phospholipid and protein organization in human erythrocytes. Arch. Biochem. Biophys. 273: 112–120.

    Google Scholar 

  3. Aruoma, O.I., Halliwell, B., Hoey, B.M., and Butler, J., 1988, The antioxi-dant action of taurine, hypotaurine and their metabolic precursors. Biochem. J. 256:251–255.

    Google Scholar 

  4. Aruoma, O.I., Halliwell, B., Hoey, B.M., and Butler, J., 1989, The antioxidant action ofN-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide and hypochlorous acid. Free Rad. Biol. Med. 6:593–597.

    Google Scholar 

  5. Azuma, J., Hamaguchi, T., Ohta, H., Takihara, K., Awata, N., Sawamura, A., Harada, H., and Kishimoto, S., 1987, Calcium overload-induced myo-cardial damage caused by isoproterenol and by adriamycin: possible role of taurine in its prevention. In The Biology of Taurine. Methods and Mechan-isms (R.J. Huxtable, F. Franconi, and A. Giotti, eds.), Plenum Press, New York, NY, pp. 167–179..

    Google Scholar 

  6. Banks, M.A., Porter, D.W., Martin, W.G., and Castranova, V., 1991, Ozone-induced lipid peroxidation and membrane leakage in isolated rat alveolar macrophages: protective effects of taurine. J. Nutr. Biochem. 2:308–313.

    Google Scholar 

  7. Beutler, E., Robson, M., and Buttenwieser, E., 1957, The mechanism of glutathione destruction and protection in drug-sensitive and non-sensitive erythrocytes. In vitro studies. J. Clin. Invest. 36:617–628.

    Google Scholar 

  8. Brunori, M., Falcioni, G., Fioretti, E., Giardina, B., and Rotilio, G., 1975, Formation of superoxide in the autoxidation of the isolated a and β chains of human hemoglobin and its involvement in hemichrome precipitation. Eur. J. Biochem. 53:99–104.

    Google Scholar 

  9. Buege, J.,A., and Aust, S.D., 1978, Microsomal lipid peroxidation, In Methods ofEnzymology, vol. 52, (S. Fleischer and L. Packer, eds.), Academic Press, New York, NY, pp. 302–310.

    Google Scholar 

  10. Cañas, P., Guerra, R., and Valenzuela, A., 1989, Antioxidant properties of hypotaurine: comparison with taurine, glutathione and β-alanine. Nutr. Rep. Int. 39:433–438.

    Google Scholar 

  11. Clemens, M.R., and Waller, H.D., 1987, Lipid peroxidation in erythrocytes. Chem. Phys. Lipids 45:251–268.

    Google Scholar 

  12. Cohen, G., and Hochstein, P., 1964, Generation of hydrogen peroxide in erythrocytes by hemolytic agents. Biochemistry 3:895–900.

    Google Scholar 

  13. Cohen, G., and Hochstein, P., 1965. In vivo generation of H2O2 in mouse erythrocytes by hemolytic agents. J. Pharmacol. Exp. Therap. 147: 139–143

    Google Scholar 

  14. Ebrahim, A.S., and Sakthisekaran, D., 1997, Effect of vitamin E and taurine treatment on lipid peroxidation and antioxidant defense in perchloroethyl-ene-induced cytotoxicity in mice. Nutr. Biochem. 8:270–274.

    Google Scholar 

  15. Ellman, G.L., 1959, Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82: 70–77.

    Google Scholar 

  16. Ferrali, M., Signorini, C., Ciccoli, L., and Comporti, M., 1992, Iron release and membrane damage in erythrocytes exposed to oxidizing agents, phenylhydrazine, divicine and isouramil. Biochem. J. 285:295–391.

    Google Scholar 

  17. French, J.K., Winterbourn, C.C., and Carrell, R.W., 1978, Mechanism of oxyhaemoglobin breakdown on reaction with acetylphenylhydrazine. Biochem. J. 173: 19–26.

    Google Scholar 

  18. Giri, S.N., and Wang, Q., 1992, Taurine and niacin offer a novel therapeutic modality in prevention of chemically-induced pulmonary fibrosis in hamsters. In Taurine (J.B. Lombardini, S.W. Schaffer, and J. Azuma., eds.), Plenum Press, New York, NY, pp.329–340.

    Google Scholar 

  19. Goldberg, B., and Stem, A., 1975, The generation of superoxide by the inter-action of the hemolytic agent, phenylhydrazine, with human hemoglobin. J. Biol. Chem. 250:2401–2403.

    Google Scholar 

  20. Goldberg, B., Stem, A., and Peisach, J., 1976, The mechanism of superoxide anion generation by the interaction of phenylhydrazine with hemoglobin. J. Biol. Chem. 251:3045–3051.

    Google Scholar 

  21. Goldberg, B., and Stern, A., 1977, The mechanism of oxidative hemolysis produced by phenylhydrazine. Mol. Pharmacol. 132:832–839.

    Google Scholar 

  22. Gutteridge, J.M.C., 1986, Iron promoters of the Fenton reaction and lipid peroxidation can be released from haemoglobin by peroxides. FEBS Lett. 201:291–295.

    Google Scholar 

  23. Hill, H.A.O., and Thornalley, P.J., 1981, Phenyl radical production during the oxidation of phenylhydrazine and in phenylhydrazine-induced haemo-lysis. FEBS Lett. 125:235–238.

    Google Scholar 

  24. Huxtable, R.J., and Sebring, L.A., 1986, Towards a unifying theory for the actions of taurine. Trends Pharmacol. Sci. 7:481–485.

    Google Scholar 

  25. Imanishi, H., Nakai, T., Abe, T., and Takino, T., 1985, Role of free radical scavengers on phenylhydrazine induced hemolysis in rat. Acta Vitaminol. Enzymol. 7:71–76.

    Google Scholar 

  26. Itano, H.A., Hirota, K., and Hosokawa, K., 1975, Mechanism of induction of haemolytic anemia by phenylhydrazine. Nature 256:665–667.

    Google Scholar 

  27. Itano, H.A., Hosokawa, K., and Hirota, K., 1976, Induction of haemolytic anemia by sub-stituted phenylhydrazines. Br. J., Haematol. 32:99–104.

    Google Scholar 

  28. Itano, H.A., and Mannen, S., 1976, Reactions of phenyldiazene and ring-substituted phenyldiazenes with ferrihemoglobin. Biochim. Biophys, Acta 421:87–96.

    Google Scholar 

  29. Itano, H.A., Hirota, K., and Vedvick, T,S, 1977, Ligands and oxidants in ferrihemochrome formation and oxidative hemolysis. Proc. Natl,. Acad, Sci. USA 74:2556–2560.

    Google Scholar 

  30. Jain, S.K., and Subrahmanyam, D., 1978, Life span of phenylhydrazine-induced reticulocytes in albino rats. Indian J. Exp. Biol. 16:255–257.

    Google Scholar 

  31. Jain, S.K., and Hochstein, P., 1979, Generation of superoxide radicals by hydrazine: its role in phenylhydrazine-induced hemolytic anemia. Biochim. Biophys. Acta 586: 128–136.

    Google Scholar 

  32. Keilin, D., and Hartree, E.F., 1951, Purification of horse-radish peroxidase and comparison of its properties with those of catalase and methemoglobin. Biochem. J. 49:88–106.

    Google Scholar 

  33. Malone, J.I., Benford, S.A., and Malone Jr., J., 1993, Taurine prevents galactose-induced cataracts. J. Diab. Comp. 7:44–48.

    Google Scholar 

  34. Misra, H.P., and Fridovich, I., 1876, The oxidation of phenylhydrazine: superoxide and mechanism. Biochemistry 15:681–687.

    Google Scholar 

  35. Moldeus, P., Cotgreave, LA., and Berggren, M., 1986, Lung protection by a thiolcontaining antioxidant: N-acetylcysteine. Respiration 50 (Suppl 1):31–42.

    Google Scholar 

  36. Nakamura, T., Ogasawara, M., Koyama, I., Nemoto, M., and Yoshida, T., 1993, The protective effect of taurine on the biomembrane against damage produced by oxygen radi-cals. Biol. Pharm. Bull. 16:970–972.

    Google Scholar 

  37. Nakashima, T., Taniko, T., and Kuriyama, K., 1982, Therapeutic effect of taurine admini-stration on carbon tetrachloride-induced hepatic injury. Japan. J. Pharmacol. 32:583–589.

    Google Scholar 

  38. Nakashima, T., Takino, T., and Kuriyama, K., 1983, Pretreatment with taurine facilitates hepatic lipid peroxide formation associated with carbon tetrachloride intoxication. Japan. J. Pharmacol. 33:515–523.

    Google Scholar 

  39. Nakashima, T., Seto, Y., Nakajima, T., Shima, T., Sakamoto, Y., Cho, N., Sano, A., Iwai, M., Kagawa, K., Okanoue, T., and Kashima, K., 1990, Calcium-associated cytoprotective effect of taurine on the calcium and oxygen paradoxes in isolated rat hepatocytes. Liver 10: 167–172.

    Google Scholar 

  40. Nakashima, T., Shima, T., Sakai, M., Yama, H., Mitsuyoshi, H., Inaba, K., Matsumoto, Y., Sakamoto, K., Kashima, K., and Nishikawa, H., 1996, Evidence of a direct action of taurine and calcium on biological membranes. Biochem. Pharmacol. 52: 173–176.

    Google Scholar 

  41. Ogiso, T., Ito, Y., Iwaki, M., Nakanishi, K., and Saito, H., 1989, Effect of phenylhydrazine-induced structural alterations of human erythrocytes on basic drug peroxidation. Chem Pharm, Bull, 37:430–434.

    Google Scholar 

  42. Orringer, E.P., and Parker, J.C., 1977, Selective increase of potassium permeability in red blood cells exposed to acetylphenylhydrazine. Blood 50: 1013–1021.

    Google Scholar 

  43. Pasantes-Morales, H., and Cruz, C., 1985, Taurine and hypotaurine inhibit light-induced lipid peroxidation and protect rod outer segment structure outer segments. Brain Res. 330:154–157.

    Google Scholar 

  44. Peisach, J., Blumberg, W.E., and Rachmilewitz, E.A., 1975, The demons-tration of ferri-hemichrome intermediates in Heinz body formation following the reduction of oxyhemo-globin A by acetylphenylhydrazine. Biochim. Biophys. Acta 393:404–418.

    Google Scholar 

  45. Petty, H.R., Zhou, M-J., and Zheng, Z., 1991, Oxidative damage by phenylhydrazine di-minishes erythrocyte anion transport. Biochim. Biophys. Acta 1064:308–314.

    Google Scholar 

  46. Pion, P.D., Kittlepon, M.D., Rogers, O.R., and Moms, J.G., 1987, Myocardial failure in cats associated with low plasma taurine. Science 237:764–768.

    Google Scholar 

  47. Pokhrel, P.K., and Lau-Cam, C.A., 1999, Protection by taurine and structurally related sulfur-containing compounds against erythrocyte membrane damage by hydrogen peroxide. This volume.

    Google Scholar 

  48. Redmond, H.P., Wang, J.H., and Bouchier-Hayes, D., 1996, Taurine attenuates nitric oxide and reactive oxygen intermediate-dependent hepatocyte injury. Arch. Surg. 131:1280–1287.

    Google Scholar 

  49. Rodkey, F.L., and O'Neal, J.D., 1974, Effects of carboxymethemoglobin on the determination of methemoglobin in blood. Biochem. Med. 9:261–270.

    Google Scholar 

  50. Saito, S., and Itano, H.A., 1981. β-meso-Phenylbiliverdin IXα and N-phenylprotoporphyrin IX, products of the reaction of phenylhydrazine with oxyhemoglo-bin. Proc. Natl. Acad. Sci. USA 78:5508???5508???5512.

    Google Scholar 

  51. Sharabani, M., Plotkin, B., and Aviram, I. (1984) Lipid peroxidation in red blood cell membranes. Cell. Mol Biol. 30:329–336.

    PubMed  CAS  Google Scholar 

  52. Sharma, R., and Premachandra, B.R., 1991, Membrane bound hemoglobin as a marker of oxidative injury in adult and neonatal red blood cells. Biochem. Med. Met. Biol. 46:33–44.

    Google Scholar 

  53. Shi, X., Flynn, D.C., Porter, D.W., Leonard, S.S., Vallyathan, V., and Castranova, V., 1997, Efficacy of taurine based compounds as hydroxyl radical scavengers in silica induced peroxidation. Ann. Clin. Lab. Med. 27:365–373.

    Google Scholar 

  54. Stem, A., 1989, Drug-induced oxidative denaturation in red blood cells. Semin, Hematol, 26:301–306.

    Google Scholar 

  55. Tadolini, B., Pintus, G., Pinna, G.G., Bennardini, F., and Franconi, F., 1995, Effects of taurine and hypotaurine on lipid peroxidation. Biochem. Biophys. Res. Commun. 213:820–826.

    Google Scholar 

  56. Thornalley, P.J., 1984, The haemolytic reactions of 1-acetyl-2-phenylhydra-zine and hydrazine: a spin trapping study. Chem. Biol. Interact. 50:339–349.

    Google Scholar 

  57. Trachtman, H., Del Pizzo, R., Futterweit, S., Levine, D., Rao, P.S., Valderrama, E., and Sturman, J.A., 1992, Taurine attenuates renal disease in chronic puromycin aminonucleoside nephropathy. Am. J. Physiol. 262:F117–F123.

    Google Scholar 

  58. Trachtman, H., Futterweit, S., and Bienokowski, R.S., 1993, Taurine prevents glucose-induced lipid peroxidation and increased collagen production in cultured rat mesangial cells. Biochem. Biophys. Res. Commun. 191:759–765.

    Google Scholar 

  59. van Caneghem, P., 1984, Influence of phenylhydrazine on the antioxidant system of the erythrocytes and the liver in mice. Biochem. Pharmacol. 33:717–720

    Google Scholar 

  60. Venkatesan, N., and Chandrakasan, G., 1994, In vivo administration of taurine and niacin modulate cyclophosphamide-induced lung injury. Eur. J. Pharmacol. 292:75–80.

    Google Scholar 

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Authors and Affiliations

  1. College of Pharmacy and Allied Health Professions, St. John’s University, 8000 Utopia Parkway, Jamaica, New York, I 1439, USA

    Prabhat K. Pokhrel & Cesar A. Lau-Cam

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  1. Prabhat K. Pokhrel
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  2. Cesar A. Lau-Cam
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Editors and Affiliations

  1. University of Florence, Florence, Italy

    Laura Della Corte

  2. University of Arizona College of Medicine, Tucson, Arizona

    Ryan J. Huxtable

  3. University of Siena, Siena, Italy

    Giampietro Sgaragli

  4. Trinity College, Dublin, Ireland

    Keith F. Tipton

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© 2002 Kluwer Academic Publishers

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Pokhrel, P.K., Lau-Cam, C.A. (2002). In Vitro and In Vivo Effects of Taurine and Structurally Related Sulfur-Containing Compounds Against Phenylhydrazine-Induced Oxidative Damage to Erythrocytes. In: Della Corte, L., Huxtable, R.J., Sgaragli, G., Tipton, K.F. (eds) Taurine 4. Advances in Experimental Medicine and Biology, vol 483. Springer, Boston, MA. https://doi.org/10.1007/0-306-46838-7_56

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  • DOI: https://doi.org/10.1007/0-306-46838-7_56

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-46447-8

  • Online ISBN: 978-0-306-46838-4

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