Abstract
In humans, altered microbial composition of the gut has been reported in different disorders, including children with autism. A number of studies comparing gut microbiota of autistic spectrum disorder patients and typically developed individuals revealed higher amount (albeit with some contradictions) of different bacteria—Bacteroidetes, Firmicutes, Proteobacteria and Tenericutes in autistic individuals. In this study differences in gut microbiota composition between children with atypical autism and childhood autism were identified. Significant differences in-between gut microbiomes in children belonging to these two groups at genus and species levels were identified.
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This work was supported by Latvian Science Council grant no. lzp-2018/2-0343 “Biomarkers of altered gut microbiome in children with autism spectra disorders.”
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Statement on the welfare of humans. Central Medical Ethics Committee at the Ministry of Health, Republic of Latvia approved the study (no. 1/19-02-12 from February 12th, 2019). Parents of all involved subjects signed informed consent form and filled-in questionaries before collecting samples. The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments.
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Nakazawa-Miklasevica, M., Daneberga, Z., Murmane, D. et al. Alterations of Gut Microbiota among Children with Autism Spectrum Disorder. Mol. Genet. Microbiol. Virol. 36 (Suppl 1), S29–S36 (2021). https://doi.org/10.3103/S0891416821050104
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DOI: https://doi.org/10.3103/S0891416821050104