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Endurance Training, Cardiovascular Function and the Aged

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Summary

Independent of disease, age-associated changes in cardiovascular function include anatomical, physiological, and haemodynamic alterations that are generally without pathological consequence. Decrements in adrenergic receptor response, arterial distensibility, ventricular compliance, and contractile performance seem to be compensated for by enhanced atrial contribution to ventricular filling, prolongation of systole, and increased reliance on the length-tension relationship of cardiac muscle. Summarily, these compensations constitute increased utilisation of the Frank-Starling mechanism.

Endurance training beneficially alters aging cardiovascular function both at rest and during exercise. An increase in end diastolic volume and ejection fraction demonstrate an enhancement of the length-tension relationship of myocardial tissue in maintaining resting and exercise cardiac outputs. The decline in maximal cardiovascular function is not preventable. It was also concluded that endurance exercise improves clinical and psychosocial factors that enhance the quality of life for elderly individuals.

Future research efforts should attempt to determine if and by what mechanisms endurance training may contribute to the regression of atherosclerotic lesions and the development of collateral vessels in senescent myocardium.

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References

  • Adams GM, deVries HA. Physiological effects of an exercise training regimen upon women aged 52 to 79. Journal of Gerontology 28: 50–55, 1973

    CAS  Google Scholar 

  • Altekruse EB, Wilmore JH. Changes in blood chemistries following a controlled exercise program. Journal of Occupational Medicine 15: 110–113, 1973

    PubMed  CAS  Google Scholar 

  • Arntzenius AC. Regression of atherossclerosis. Benefit can be expected from low LDL-C and high HDL-C. Acta Cardiologica 46: 431–438, 1991

    PubMed  CAS  Google Scholar 

  • Barry AJ, Daly JW, Pruett DR, Steinmetz JR, Page HF, et al. The effects of physical conditioning on older individuals. I. Work capacity, circulatory-respiratory function, and work electrocardiogram. Journal of Gerontology 21: 182–191, 1966

    PubMed  CAS  Google Scholar 

  • Barth JD, Arntzenius AC. Progression and regression of atherosclerosis, what roles for LDL-cholesterol and HDL-cholesterol: a perspective. European Heart Journal 12: 952–957, 1991

    PubMed  CAS  Google Scholar 

  • Bassey EJ, Bendall MJ, Pearson M. Muscle strength in the triceps surae and objectively measured customary walking activity in men and women over 65 years of age. Clinical Science 74: 85–89, 1988

    PubMed  CAS  Google Scholar 

  • Bassey J, Fentem P, Turnbull N. Reasons for advising exercise. Practitioner 231: 1605–1610, 1987

    PubMed  CAS  Google Scholar 

  • Benestad AM. Trainability of old men. Acta Medica Scandinavica 178: 321–327, 1965

    Article  PubMed  CAS  Google Scholar 

  • Bierman EL. Atherosclerosis and Aging. Federation Proceedings 37: 2832–2836, 1978

    PubMed  CAS  Google Scholar 

  • Bruce RA, Alexander ER, Li YB. Electrocardiographic responses to maximal exercise in American and Chinese population samples. In Blackburn (Ed.) Measurement in exercise electrocardiography, pp. 413–444, CC Thomas, Springfield, 1969

    Google Scholar 

  • Buskirk ER, Hodgson JL. Age and aerobic power the rate of change in men and women. Federation Proceedings 46: 1824–1829, 1987

    PubMed  CAS  Google Scholar 

  • Chung EK, Chung LS. Introduction to clinical cardiology, Karger, New York, 1983

    Google Scholar 

  • Cunningham DA, Rechnitzer PA, Howard JH, Donner AP. Exercise training of men at retirement: a clinical trial. Journal of Gerontology 42: 17–23, 1987

    PubMed  CAS  Google Scholar 

  • Davidson DM, Popp RL, Haskell WL. Echocardiographic changes during a 1 year exercise program in previously sedentary middle aged men. American Journal of Cardiology 47: 477, 1981

    Article  Google Scholar 

  • Dehn MM, Bruce RA. Longitudinal variations in maximal oxygen intake with age and activity. Journal of Applied Physiology 33: 805–807, 1972

    PubMed  CAS  Google Scholar 

  • DeMaria AN, Neumann A, Lee G, Fowler W, Mason DT. Alterations in ventricular mass and performance induced by exercise training in man evaluated by echocardiography. Circulation 57: 237–244, 1978

    Article  PubMed  CAS  Google Scholar 

  • Denis C, Chatard JC, Dormois D, Linossier MT, Geyssant A, et al. Effects of endurance training on capillary supply of human skeletal muscle on two age groups (20 and 60 years). Journal of Physiology (Paris) 81: 379–383, 1986

    CAS  Google Scholar 

  • Detrano R, Froelicher VF. Uses and limitations considering recent studies. Progress in Cardiovascular Disease 31: 173–204, 1988

    Article  CAS  Google Scholar 

  • deVries HA. Physiological effects of an exercise training regimen upon men aged 52 to 88. Journal of Gerontology 25: 325–336, 1970

    CAS  Google Scholar 

  • Dufaux B, Assman G. Plasma lipoproteins and physical activity: a review. International Journal of Sports Medicine 3: 123–136, 1982

    Article  PubMed  CAS  Google Scholar 

  • Ehsani AA, Ogawa T, Miller TR, Spina RJ, Jilke SM. Exercise training improves left ventricular systolic function in older men. Circulation 83: 95–103, 1991

    Article  Google Scholar 

  • Faria I, Frankel M. Anthropometric and physiologic profile of a cyclist — age 70. Medicine and Science in Sports and Exercise 9: 181–121, 1977

    Google Scholar 

  • Ferguson RJ, Petitclerc R, Gaston C, Lambros C, Gauthier P, et al. Effects of physical training on treadmill exercise capacity, collateral circulation and progression of coronary disease. American Journal of Cardiology 34: 764–769, 1974

    Article  PubMed  CAS  Google Scholar 

  • Fleg JL. Alterations in cardiovascular structure and function with advancing age. American Journal of Cardiology 57: 33C–44C, 1986

    Article  PubMed  CAS  Google Scholar 

  • Fleg JL, Das DN, Wright J, Lakatta EG. Age-associated changes in the components of atrioventricular conduction in apparently healthy volunteers. Journal of Gerontology 45: M95–M100, 1990

    PubMed  CAS  Google Scholar 

  • Foster VL, Hume GJE, Byrnes WC, Dickinson AL, Chatfield SJ. Endurance training for elderly women: moderate vs low intensity. Journal of Gerontology 44: M184–M178, 1989

    PubMed  CAS  Google Scholar 

  • Gerstenblith G, Lakatta EG, Weisfeldt ML. Age changes in myocardial function and exercise response. Progress in Cardiovascular Diseases 29: 16–18, 1976

    Google Scholar 

  • Gerstenblith G, Renlund DG, Lakatta, EG. Cardiovascular response to exercise in younger and older men. Federation Proceedings 46: 1834–1839, 1987

    PubMed  CAS  Google Scholar 

  • Gorman D, Brown B. Fitness and aging: an overview. Journal of Health, Physical Education, Recreation, and Dance 57: 50–51, 1986

    Google Scholar 

  • Graettinger WF. The cardiovascular response to chronic physical exertion and exercise training: an echocardiographic review. American Heart Journal 108: 1014–1018, 1984

    Article  PubMed  CAS  Google Scholar 

  • Hagberg JM, Allen WK, Seals DR, Hurley BF, Ehsani AA, et al. A hemodynamic comparison of young and older endurance athletes during exercise. Journal of Applied Physiology 58: 2041–2046, 1985

    PubMed  CAS  Google Scholar 

  • Hagberg JM, Graves JE, Limacher M, Woods DR, Leggett SH, et al. Cardiovascular responses of 70- to 79-yr-old men and women to exercise training. Journal of Applied Physiology 66: 2589–2594, 1989

    Article  PubMed  CAS  Google Scholar 

  • Heath GW, Hagberg JM, Ehsani AA, Holloszy JO. A physiological comparison of young and older endurance athletes. Journal of Applied Physiology 51: 634–640, 1981

    PubMed  CAS  Google Scholar 

  • Hickson RC, Kanakis C, Davis JR. Reduced training duration effects on aerobic power, endurance, and cardiac growth. Journal of Applied Physiology 53: 225, 1982

    PubMed  CAS  Google Scholar 

  • Higginbotham MB, Morris KG, Williams RS, Coleman RE, Cobb FR. Physiologic basis for the age-related decline in aerobic work capacity. American Journal of Cardiology 57: 1374–1379, 1986

    Article  PubMed  CAS  Google Scholar 

  • Hoppeler H, Howald H, Conley K. Endurance training in humans: aerobic capacity and structure of skeletal muscle. Journal of Applied Physiology 59: 320–327, 1985

    PubMed  CAS  Google Scholar 

  • Hossack KF, Bruce RA. Maximal cardiac function in sedentary normal men and women: comparison of age-related changes. Journal of Applied Physiology 53: 799–804, 1982

    PubMed  CAS  Google Scholar 

  • Houston ME, Bentzen H, Larsen H. Interrelationships between skeletal muscle and adaptations and performance as studied by training and retraining. Acta Medica Scandinavica 205: 163–170, 1979

    Google Scholar 

  • Inger F. Effect of endurance training on muscle fiber ATP-ase activity, capillary supply and mitochondrial content in man. Journal of Physiology (London) 294: 419–432, 1979

    Google Scholar 

  • Kanakis C. Left ventricular responses to strenuous endurance training and related training frequencies. Journal of Cardiac Rehabilitation 2: 141, 1982

    Google Scholar 

  • Kasch FW, Wallace JP, Van Camp SP. Effects of 18 years of endurance exercise on the physical work capacity of older men. Journal of Cardiopulmonary Rehabilitation 5: 308–312, 1985

    Article  Google Scholar 

  • Kattus AA, MacAlpin RN. Role of exercise in discovery evaluation and management of ischemic heart disease. Cardiovascular Clinics 1: 255–279, 1969

    Google Scholar 

  • Kavanagh T. Does exercise improve coronary collateralization? A new look at an old belief. Physician and Sportsmedicine 17: 101–110, 1989

    Google Scholar 

  • Kiessling KH, Pilstrom L, Bylund AC, Saltin B, Piehl K. Enzyme activities and morphomerty in skeletal muscle of middle aged men after training. Scandinavian Journal of Clinical Laboratory Investigation 33: 63–69, 1974

    Article  CAS  Google Scholar 

  • Kindermann W, Reindell H. Central hemodynamics in normal, well-trained and hypertensive subjects. In Landry & Orban (Eds) Sports medicine, 5th ed., pp. 43–56, Symposia Specialists, Miami, 1978

    Google Scholar 

  • Kitzman DW, Edwards WD. Minireview: Age-related changes in the anatomy of the normal human heart. Journal of Gerontology 45: M33–M39, 1990

    PubMed  CAS  Google Scholar 

  • Klausen K, Andersen LB, Pelle I. Adaptative changes in work capacity, skeletal muscle capillarization and enzymes levels during training and detraining. Acta Physiologica Scandinavica 113: 9–16, 1981

    Article  PubMed  CAS  Google Scholar 

  • Klausner SC, Schwartz AB. The aging heart. Clinics in Geriatric Medicine 1: 119–141, 1985

    PubMed  CAS  Google Scholar 

  • Konishi T, Koyama T, Aoki T, Makino K, Yamamuro M, et al. Influence of age on left ventricular performance during exercise in normal Japanese subject: Assessment by radionuclide ventriculography. Annals of Nuclear Medicine 4: 19–27, 1990

    Article  PubMed  CAS  Google Scholar 

  • Lakatta EG. Changes in cardiovascular function with aging. European Heart Journal 11 (Suppl. C): 22–29, 1990

    PubMed  Google Scholar 

  • Lakatta EG, Spurgeon HA. Effect of exercise on cardiac muscle performance in aged rats. Federation Proceedings 46: 1844–1849, 1987

    PubMed  CAS  Google Scholar 

  • Mann DL, Denenberg BS, Gash AK, Makler PT, Bove AA. Effects of age on ventricular performance during graded supine exercise. American Heart Journal 111: 108–115, 1986

    Article  PubMed  CAS  Google Scholar 

  • Massicotte D. Physiological effects on older women of a 30 week physical conditioning program. Canadian Association of Health, Physical Education, and Recreation Journal 47: 31–38, 1981

    Google Scholar 

  • Meredith CN, Frontera WR, Fisher EC, Hughes VA, Herland JC, et al. Peripheral effects of endurance training in young and old subjects. Journal of Applied Physiology 66: 2844–2849, 1989

    PubMed  CAS  Google Scholar 

  • Morgan DW, Cruise RJ. HDL-C concentrations in weight-trained, endurance-trained, and sedentary females. Physician and Sportsmedicine 14: 166–181, 1986

    Google Scholar 

  • Niinimaa V, Shephard RJ. Training and oxygen conductance in the elderly. Journal of Gerontology 33: 354–361, 1978

    PubMed  CAS  Google Scholar 

  • Nixon JV, Hallmark H, Page K, Raven PR, Mitchell JH. Ventricular performance in human hearts aged 61 to 73 years. American Journal of Cardiology 56: 932–937, 1985

    Article  PubMed  CAS  Google Scholar 

  • Nolewajka AJ, Kostuk WJ, Rechnitzer PA, Cunningham DA. Exercise and human collateralization: an angiographic and scintigraphic assessment. Circulation 60: 114–121, 1979

    Article  PubMed  CAS  Google Scholar 

  • Olsen LJ, Gertz MA, Edwards WD. Senile cardiac amyloidosis with myocardial dysfunction. Diagnosis by endomyocardial biopsy and immunohistochemistry. New England Journal of Medicine 317: 738–742, 1987

    Article  Google Scholar 

  • Ornish D, Brown SE, Scherwitz LW, Billings JH, Armstrong WT, et al. Can lifestyle changes reverse coronary heart disease? Lancet 336: 129–133, 1990

    Article  PubMed  CAS  Google Scholar 

  • Paffenbarger RS, Hyde RT, Wing AL, Hsieh CC. Physical activity, all-case mortality, and longevity of college alumni. New England Journal of Medicine 314: 605–613, 1986

    Article  PubMed  Google Scholar 

  • Perri S, Templer DI. The effects of an exercise program on psychological variables in older adults. International Journal of Aging and Human Development 20: 167–170, 1985

    Article  Google Scholar 

  • Pollock ML, Dawson GA, Miller Jr HS, Ward A, Cooper D, et al. Physiologic responses of men 49 to 65 years of age to endurance training. Journal of the American Geriatrics Society 24: 97–104, 1976

    PubMed  CAS  Google Scholar 

  • Pollock ML, Miller HS, Wilmore J. A profile of a champion distance runner: age 60. Medicine and Science in Sports and Exercise 6: 118–121, 1974

    CAS  Google Scholar 

  • Pomerance A. Aging and degenerative changes. In Pomerance & Davis (Eds) The pathology of the heart, pp. 49–79, Blackwell Scientific, London, 1975

    Google Scholar 

  • Posner JD, Gorman KM, Klein HS, Woldow A. Exercise capacity in the elderly. American Journal of Cardiology 57: 52C–58C, 1986

    Article  PubMed  CAS  Google Scholar 

  • Rerych SK, Scholz PM, Sabiston Jr DC, Jones RH. Effects of exercise training on left ventricular function in normal subjects: a longitudinal study by radionuclide angiography. American Journal of Cardiology 45: 244–252, 1980

    Article  PubMed  CAS  Google Scholar 

  • Rodbard S. Vascular caliber. Cardiology 60: 4–49, 1975

    Article  PubMed  CAS  Google Scholar 

  • Rodeheffer RJ, Gerstenblith G, Becker LC, Gleg JL, Weisfeldt ML, et al. Exercise cardiac output is maintained with advancing age in healthy human subjects: Cardiac dilatation and increased stroke volume compensate for a diminished heart rate. Circulation 69: 203–213, 1984

    Article  PubMed  CAS  Google Scholar 

  • Rost R, Sreisbach W, Hollmann W. Hemodynamic changes in 50- to 70- year-old men due to endurance training. In Landry & Orban (Eds) Sports medicine, Vol. 5, pp. 121–124, Symposia Specialist, Miami, 1978

    Google Scholar 

  • Sagiv M, Fisher N, Yaniv A, Rudoy, J. Effect of running versus isometric training programs on healthy elderly at rest. Gerontology 35: 72–77, 1989

    Article  PubMed  CAS  Google Scholar 

  • Schaible TF, Scheuer J. Cardiac adaptations to chronic exercise. Progress in Cardiovascular Diseases 27: 297–324, 1985

    Article  PubMed  CAS  Google Scholar 

  • Schocken DD, Blumenthal JA, Port S, Hindle P, Coleman RE. Physical conditioning and left ventricular performance in the elderly: assessment by radionuclide angiocardiography. American Journal of Cardiology 52: 359–364, 1983

    Article  PubMed  CAS  Google Scholar 

  • Seals DR, Hagberg JM, Hurley BF, Ehsani AA, Holloszy JO. Endurance training in older men and women. I. Cardiovascular responses to exercise. Journal of Applied Physiology 57: 1024–1029, 1984

    PubMed  CAS  Google Scholar 

  • Spencer G. Projections of the population of the United States by age, sex, and race: 1988 to 2080. Current Population Reports, Population Estimates and Projections, Series P-25, No 1018, US Department of Commerce, Bureau of the Census, Washington, DC, 1989

    Google Scholar 

  • Spurgeon HA, Steinbach MF, Lakatta EG. Chronic exercise prevents characteristic age-related changes in rat cardiac contraction. American Journal of Physiology 244: H513–H518, 1983

    PubMed  CAS  Google Scholar 

  • Stamford BA. Physiological effects of training upon institutionalized geriatric men. Journal of Gerontology 27: 451–455, 1972

    PubMed  CAS  Google Scholar 

  • Stamford BA. Exercise and the elderly. Exercise and Sports Science Reviews 16: 341–379, 1988

    CAS  Google Scholar 

  • Suominen HE, Heikkinen E, Liesen H, Michel D, Hollmann W. Effects of 8 weeks’ endurance training on skeletal muscle metabolism in 56–70 year old sedentary men. European Journal of Applied Physiology 37: 173–180, 1977

    Article  CAS  Google Scholar 

  • Tsuji H, Ebizawa T, Morikawa Y, Kitamura H, Furukawa K, et al. Influence of exercise training on left ventricular performance investigated by two-dimensional echocardiography. Journal of Cardiography 16: 457–464, 1986

    PubMed  CAS  Google Scholar 

  • Tzankoff SP, Robinson S, Pyke FS, Brawn CA. Physiological adjustments to work in older men as affected by physical training. Journal of Applied Physiology 33: 346–350, 1972

    PubMed  CAS  Google Scholar 

  • Upton SJ. Comparative physiological profiles among young and middle-aged female distance runners. Medicine and Science in Sports and Exercise 16: 67, 1984

    PubMed  CAS  Google Scholar 

  • Van Camp SP, Boyer JL. Exercise guidelines for the elderly (Part 2). Physician and Sportsmedicine 17: 83–88, 1989

    Google Scholar 

  • Van Camp SP, Boyer JL. Cardiovascular aspects of aging (Part 1). Physician and Sportsmedicine 17: 121–130, 1989

    Google Scholar 

  • Walsh RA. Cardiovascular effects of the aging process. American Journal of Medicine 82: 34–39, 1987

    Article  PubMed  CAS  Google Scholar 

  • Weisfeldt ML. Aging of the cardiovascular system. Editorial. New England Journal of Medicine 303: 1172–1174, 1980a

    Article  PubMed  CAS  Google Scholar 

  • Weisfeldt ML. Research on aging. In Weisfeldt (Ed.) The aging heart: its function and response to stress, Raven Press, New York, 1980b

    Google Scholar 

  • Wolfe LA, Cunningham DA, Rechnitzer PA. Effects of endurance training on left ventricular dimensions in healthy men. Journal of Applied Physiology 47: 207, 1979

    PubMed  CAS  Google Scholar 

  • Wood PD, Haskell WL. Plasma lipoprotein distributions in male and female runners. Annals of the New York Academy of Sciences 301: 748–763, 1977

    Article  PubMed  CAS  Google Scholar 

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Green, J.S., Crouse, S.F. Endurance Training, Cardiovascular Function and the Aged. Sports Medicine 16, 331–341 (1993). https://doi.org/10.2165/00007256-199316050-00004

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