Skip to main content
SpringerLink
Log in

Signal Enhancement by Crossing the Sample Flow at a Small Angle against the Laser Beam in Multiphoton Ionization Mass Spectrometry

  • Original Papers
  • Published:
Analytical Sciences Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Abstract

To enhance sensitivity in multiphoton ionization/time-of-flight mass spectrometry, the sample, in the form of an effusive molecular flow, was introduced at a small angle relative to the laser beam. This approach enlarged the volume of interaction between the sample and the laser beam, thus increasing the number of ions formed by multiphoton ionization. The sensitivity obtained using this technique was compared with that obtained using a previous method based on the off-axis sample introduction technique with detection limits for organic hydrocarbons at the subfemtogram level. The detection limit was examined for dioxins and an improvement of 2.5 ± 0.4 fold was found. The technique developed herein is applicable for practical ultratrace analysis of persistent organic pollutants.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. T. Todaka, H. Hirakawa, J. Kajiwara, T. Hori, K. Tobishi, D. Onozuka, T. Iida, T. Yoshimura, and M. Furue, Fukuoka Acta Med., 2007, 98, 222.

    CAS  PubMed  Google Scholar 

  2. K. Tsukimura, H. Uchi, S. Tokunaga, F. Yasukawa, T. Chiba, J. Kajiwara, T. Hirata, and M. Furue, Chemosphere, 2013, 90, 1581.

    Article  Google Scholar 

  3. J. Koponen, P. Rantakokko, R. Airaksinen, and H. Kiviranta, J. Chromatogr. A, 2013, 1309, 48.

    Article  CAS  PubMed  Google Scholar 

  4. C. Manzano, E. Hoh, and S. L. M. Simonich, J. Chromatogr. A, 2013, 1307, 172.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. U. Raab, M. Albrecht, U. Preiss, W. Völkel, U. Schwegler, and H. Fromme, Chemosphere, 2013, 93, 461.

    Article  CAS  PubMed  Google Scholar 

  6. Y. Watanabe-Ezoe, X. Li, T. Imasaka, T. Uchimura, and T. Imasaka, Anal. Chem., 2010, 82, 6519.

    Article  CAS  PubMed  Google Scholar 

  7. T. Shimizu, Y. Watanabe-Ezoe, S. Yamaguhchi, H. Tsukatani, T. Imasaka, S. Zaitsu, T. Uchimura, and T. Imasaka, Anal. Chem., 2010, 82, 3441.

    Article  CAS  PubMed  Google Scholar 

  8. T. Matsui, K. Fukazawa, M. Fujimoto, and T. Imasaka, Anal. Sci., 2012, 28, 445.

    Article  CAS  PubMed  Google Scholar 

  9. Y. M. Huang and M. Sulkes, Rev. Sci. Instrum., 1994, 65, 3868.

    Article  CAS  Google Scholar 

  10. T. Muller and P. H. Vaccaro, Rev. Sci. Instrum., 1998, 69, 406.

    Article  CAS  Google Scholar 

  11. T. Onoda, G. Saito, and T. Imasaka, Anal. Chim. Acta, 2000, 412, 213.

    Article  CAS  Google Scholar 

  12. T. Uchimura, S. Yamaguchi, and T. Imasaka, Chem. Lett., 2009, 38, 744.

    Article  CAS  Google Scholar 

  13. J. Matsumoto, G. Saito, and T. Imasaka, Anal. Sci., 2002, 18, 567.

    Article  CAS  PubMed  Google Scholar 

  14. J. Matsumoto, B. Nakano, and T. Imasaka, Anal. Sci., 2003, 19, 379.

    Article  CAS  PubMed  Google Scholar 

  15. J. Matsumoto, B. Nakano, and T. Imasaka, Anal. Sci., 2003, 19, 383.

    Article  CAS  PubMed  Google Scholar 

  16. S. R. Goates, C. H. Sin, J. K. Simons, K. E. Markides, and M. L. Lee, J. Microcolumn Sep., 1989, 1, 207.

    Article  CAS  Google Scholar 

  17. N. Kirihara, K. Takahashi, N. Kitada, M. Tanaka, and Y. Suzuki, Rev. Sci. Instrum., 2006, 77, 094101-1.

    Article  Google Scholar 

  18. D. J. Funk, R. C. Oldenborg, D. P. Dayton, J. P. Lacosse, J. A. Draves, and T. J. Logan, Appl. Spectrosc., 1995, 49, 105.

    Article  CAS  Google Scholar 

  19. “Tentative Manual for the Measurement of Dioxins in Human Blood”, 2000, Ministry of Health, Labour and Welfare, Tokyo, http://www.nihs.go.jp/mhlw/chmical/dioxin/h121222/report.pdf.

  20. A. Dubietis, G. Valiulis, R. Danielius, and A. Piskarskas, Pure Appl. Opt., 1998, 7, 271.

    Article  CAS  Google Scholar 

  21. X. Delen, Y. Zaoulter, I. Martial, N. Aubry, J. Didierjean, C. Honninger, E. Mottay, F. Balembois, and P. Georges, Opt. Lett., 2013, 38, 109.

    Article  CAS  PubMed  Google Scholar 

  22. Y. Zaoulter, F. Guichard, L. Daniault, M. Hanna, F. Morin, C. Honninger, E. Mottay, F. Druon, and P. Georges, Opt. Lett., 2013, 38, 106.

    Article  Google Scholar 

  23. C. H. Hung, H. P. Ho, M. T. Lin, C. Y. Chen, Y. Y. Shu, and M. R. Lee, J. Chromatogr. A, 2012, 1265, 1.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi, Fukuoka, 819-0395, Japan

    Taiki Matsui & Totaro Imasaka

  2. Division of Optoelectronics and Photonics, Center for Future Chemistry, Kyushu University, 744 Motooka, Nishi, Fukuoka, 819-0395, Japan

    Totaro Imasaka

Authors
  1. Taiki Matsui
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Totaro Imasaka
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Taiki Matsui.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Matsui, T., Imasaka, T. Signal Enhancement by Crossing the Sample Flow at a Small Angle against the Laser Beam in Multiphoton Ionization Mass Spectrometry. ANAL. SCI. 30, 445–449 (2014). https://doi.org/10.2116/analsci.30.445

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2116/analsci.30.445

Keywords

Search

Navigation