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Time-correlated Single Ion Counting Mass Spectrometer with Long and Short Time-of-Flight Tubes and an Evaluation of Its Performance for Use in Trace Analysis of Allergenic Substances

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Abstract

An analyte molecule was ionized using a femtosecond laser as the ionization source and was measured by a twin-type time-of-flight mass spectrometer with long (42 cm) and short (6.4 cm) flight tubes. The signal was measured using an analog signal digitizer and a time-correlated single ion counting system, and performance was evaluated by comparing data obtained from both instruments. The short mass spectrometer had a mass resolution of 450 and was used in the trace analysis of allergenic substances in a fragrance.

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Acknowledgments

This research was supported by a Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science (JSPS KAKENHI Grant Numbers JP26220806 and JP20H02399) and the Program of Progress 100 of Kyushu University.

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Correspondence to Tomoko Imasaka.

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Ju, T., Yoshinaga, K., Imasaka, T. et al. Time-correlated Single Ion Counting Mass Spectrometer with Long and Short Time-of-Flight Tubes and an Evaluation of Its Performance for Use in Trace Analysis of Allergenic Substances. ANAL. SCI. 36, 539–543 (2020). https://doi.org/10.2116/analsci.19SBP03

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  • DOI: https://doi.org/10.2116/analsci.19SBP03

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