Skip to main content
SpringerLink
Log in

Microstructure, mechanical, in vitro corrosion and biocompatibility response study of as-cast and as-rolled Mg–5Zn–0.5Zr alloy

  • Original Paper
  • Published:
MRS Advances Aims and scope Submit manuscript

A Correction to this article was published on 08 March 2022

This article has been updated

Abstract

Magnesium (Mg) alloys are attractive biodegradable metal used for medical implant applications. In the present investigation, as-cast and as-rolled Mg–5Zn–0.5Zr alloys were studied for microstructural, mechanical, corrosion behaviour and in vitro biocompatibility. The microstructural changes due to hot rolling strongly influenced the micro-hardness, elastic modulus and corrosion behaviour of the alloy. The micro-hardness of the alloy increased from 66 ± 5 HV in as-cast condition to 84 ± 3 HV after rolling. The corrosion resistance of the alloy decreased after rolling whereas both as-cast and as-rolled alloys showed adequate biocompatibility with mouse osteoblast precursor cell line (MC3T3-E1). In summary, the alloy has potential for customized degradable implant applications and the degradation behaviour depends on the processing route.

Graphic abstract

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Data availability

Data sharing not applicable to this article as no datasets were generated or analysed during current study.

Change history

References

  1. F. Witte, A. Eliezer, Biodegradable metals. Degrad. Implant Mater. 9781461439, 93–109 (2012). https://doi.org/10.1007/978-1-4614-3942-4_5

    Article  Google Scholar 

  2. A. Chaya, S. Yoshizawa, K. Verdelis, N. Myers, B.J. Costello, D.T. Chou, S. Pal, S. Maiti, P.N. Kumta, C. Sfeir, Acta Biomater. 18, 262–269 (2015). https://doi.org/10.1016/j.actbio.2015.02.010

    Article  CAS  Google Scholar 

  3. U. Riaz, I. Shabib, W. Haider, J. Biomed. Mater. Res. - Part B Appl. Biomater. (2018). https://doi.org/10.1002/jbm.b.34290

    Article  Google Scholar 

  4. L. Xu, G. Yu, E. Zhang, F. Pan, K. Yang, J. Biomed. Mater. Res. Part A. 83A, 703–711 (2007). https://doi.org/10.1002/jbm.a.31273

    Article  CAS  Google Scholar 

  5. D. Hong, P. Saha, D.T. Chou, B. Lee, B.E. Collins, Z. Tan, Z. Dong, P.N. Kumta, Acta Biomater. 9, 8534–8547 (2013). https://doi.org/10.1016/j.actbio.2013.07.001

    Article  CAS  Google Scholar 

  6. Z.G. Huan, M.A. Leeflang, J. Zhou, L.E. Fratila-Apachitei, J. Duszczyk, J. Mater. Sci. Mater. Med. 21, 2623–2635 (2010). https://doi.org/10.1007/s10856-010-4111-8

    Article  CAS  Google Scholar 

  7. X.N. Gu, N. Li, Y.F. Zheng, L. Ruan, Mater. Sci. Eng. B Solid-State Mater. Adv. Technol. 176, 1778–1784 (2011). https://doi.org/10.1016/j.mseb.2011.05.032

    Article  CAS  Google Scholar 

  8. J. Chen, L. Tan, K. Yang, Bioact. Mater. 2, 19–26 (2017). https://doi.org/10.1016/j.bioactmat.2016.12.002

    Article  Google Scholar 

  9. D. Orlov, K.D. Ralston, N. Birbilis, Y. Estrin, Acta Mater. 59, 6176–6186 (2011). https://doi.org/10.1016/j.actamat.2011.06.033

    Article  CAS  Google Scholar 

  10. X. Chen, L. Liu, F. Pan, L. Qiao, Mater. Res. Innov. 18, S4187–S4192 (2014). https://doi.org/10.1179/1432891714Z.000000000672

    Article  CAS  Google Scholar 

  11. X. Gong, W. Gong, S.B. Kang, J.H. Cho, X. Gong, W. Gong, S.B. Kang, J.H. Cho, Mater. Res. 18, 360–364 (2015)

    Article  Google Scholar 

  12. Y.T. Chen, F.Y. Hung, Y.L. Lin, C.Y. Lin, J. Orthop. Sci. 25, 1107–1115 (2020)

    Article  Google Scholar 

  13. M.V. Markushev, D.R. Nugmanov, O. Sitdikov, A. Vinogradov, Mater. Sci. Eng. A. 709, 330–338 (2018)

    Article  CAS  Google Scholar 

  14. G.M. Naik, G.D. Gote, S. Narendranath, S.S. Satheesh Kumar, IOP Conf. Ser. Mater. Sci. Eng. 577 (2019)

  15. C. Shuai, Y. Yang, P. Wu, X. Lin, Y. Liu, Y. Zhou, P. Feng, X. Liu, S. Peng, J. Alloys Compd. 691, 961–969 (2017)

    Article  CAS  Google Scholar 

  16. M. Zhang, C. Chen, C. Liu, S. Wang, Metals (Basel). 8, 1–19 (2018)

    Google Scholar 

  17. A. Hadadzadeh, F. Mokdad, M.A. Wells, D.L. Chen, Mater. Sci. Eng. A. 720, 180–188 (2018)

    Article  CAS  Google Scholar 

  18. D. Nugmanov, M. Knezevic, M. Zecevic, O. Sitdikov, M. Markushev, I.J. Beyerlein, Mater. Sci. Eng. A. 713, 81–93 (2018)

    Article  CAS  Google Scholar 

  19. A.M. Galow, A. Rebl, D. Koczan, S.M. Bonk, W. Baumann, J. Gimsa, Biochem. Biophys. Rep. 10, 17–25 (2017)

    Google Scholar 

  20. Z. Zhen, X. Liu, T. Huang, T. Xi, Y. Zheng, Mater. Sci. Eng. C. 46, 202–206 (2015)

    Article  CAS  Google Scholar 

  21. W. Oliver, G.P.-J. of materials research, undefined 1992, An improved technique for determining hardness and elastic modulus using load and displacement sensing indentation experiments, Cambridge

  22. A. Jana, M. Das, V.K. Balla, J. Alloys Compd. 821, 153462 (2020)

    Article  CAS  Google Scholar 

Download references

Acknowledgements

AJ acknowledges the financial aid from Department of Science and Technology, New Delhi, India (SR/WOS-A/ET-44/2016).Authors thanks Prof. Uday Chakkingal, Department of MME, IIT Madras for his help in rolling experiments.

Author information

Authors and Affiliations

  1. CSIR-Central Glass and Ceramic Research Institute (CGCRI), Kolkata, 700032, India

    Anuradha Jana, Mitun Das & Vamsi Krishna Balla

  2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India

    Anuradha Jana, Mitun Das & Vamsi Krishna Balla

  3. Advanced Technology Development Centre, IIT Kharagpur, Kharagpur, 721302, India

    Sourav Dutta

  4. Department of Metallurgical and Materials Engineering, IIT Kharagpur, Kharagpur, 721302, India

    Mangal Roy

  5. Department of Metallurgical and Materials Engineering, IIT Madras, Chennai, 600 036, India

    U. Aravind

Authors
  1. Anuradha Jana
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sourav Dutta
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mangal Roy
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. U. Aravind
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Mitun Das
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Vamsi Krishna Balla
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Mitun Das or Vamsi Krishna Balla.

Ethics declarations

Conflict of interest

The authors declare no conflict of interest.

Additional information

This article was updated to correct affiliation 2.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (DOCX 156 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Jana, A., Dutta, S., Roy, M. et al. Microstructure, mechanical, in vitro corrosion and biocompatibility response study of as-cast and as-rolled Mg–5Zn–0.5Zr alloy. MRS Advances 6, 472–476 (2021). https://doi.org/10.1557/s43580-021-00056-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1557/s43580-021-00056-7

Search

Navigation