Skip to main content
Log in

Chronic Pain in Multiple Sites and Dementia: A Vicious Cycle?

  • Letter to the Editor
  • Published:
The Journal of Prevention of Alzheimer's Disease Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Availability of Data and Materials

The datasets used and/or analysed during the current study are available from the corresponding author upon reasonable request.

References

  1. Zhao W, Zhao L, Chang X, Lu X, Tu Y. Elevated dementia risk, cognitive decline, and hippocampal atrophy in multisite chronic pain. Proc Natl Acad Sci U S A 2023;120(9):e2215192120.https://doi.org/10.1073/pnas.2215192120.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  2. Tian J, Jones G, Lin X, et al. Association between chronic pain and risk of incident dementia: findings from a prospective cohort. BMC Med 2023;21(1):169.https://doi.org/10.1186/s12916-023-02875-x.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Johnston KJA, Adams MJ, Nicholl BI, et al. Genome-wide association study of multisite chronic pain in UK Biobank. PLoS Genet 2019;15(6):e1008164–e.https://doi.org/10.1371/journal.pgen.1008164.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  4. Lambert JC, Ibrahim-Verbaas CA, Harold D, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease. Nat Genet 2013;45(12):1452–8.https://doi.org/10.1038/ng.2802.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  5. Cravello L, Di Santo S, Varrassi G, et al. Chronic Pain in the Elderly with Cognitive Decline: A Narrative Review. Pain and Therapy 2019;8(1):53–65.https://doi.org/10.1007/s40122-019-0111-7

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Funding

This work was supported by the Australian National Health and Medical Research Council (1173155, 1117037 and 1157535). The funder had no role in the study design; data analysis, and interpretation; manuscript preparation, review, and approval.

Author information

Authors and Affiliations

Authors

Contributions

Study concept and design: JT, FP; Statistical analysis: JT, LX; Drafting of the manuscript: JT; Critical revision of the manuscript: JT, GJ, XL, YZ, AK, JV, FP.

Corresponding author

Correspondence to Feng Pan.

Ethics declarations

The authors have no conflicts of interest to declare.

Additional information

How to cite this article: J. Tian, G. Jones, X. Lin, et al. Letter to the Editor: Chronic Pain in Multiple Sites and Dementia: A Vicious Cycle? J Prev Alz Dis 2023; https://doi.org/10.14283/jpad.2023.120

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tian, J., Jones, G., Lin, X. et al. Chronic Pain in Multiple Sites and Dementia: A Vicious Cycle?. J Prev Alzheimers Dis 11, 527–528 (2024). https://doi.org/10.14283/jpad.2023.120

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.14283/jpad.2023.120

Navigation