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Methods of extraction, preconcentration, and determination of quercetin

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Abstract

State-of-the-art methods of the extraction, preconcentration, and determination of quercetin and other flavonoids are described. Different methods of sample preparation of real samples are compared, including solvent extraction from solid matrices and liquid-liquid, supercritical fluid, and solid-phase extraction. The following main determination methods are discussed: HPLC, thin-layer chromatography, capillary electrophoresis, spectrophotometry, luminescence, and electrochemical methods. Some examples of quercetin determination in biological fluids, food products, biologically active food supplements, pharmaceutical preparations, and plant samples are given.

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References

  1. Yashin, Ya.I., Ryzhnev, V.Yu., Yashin, A.Ya., and Chernousova, N.I., Prirodnye antioksidanty. Soderzhanie v pishchevykh produktakh i ikh vliyanie na zdorov’e i starenie cheloveka (Natural Antioxidants: The Content in Foods and Their Effect on Human Health and Aging), Moscow: TransLit, 2009.

    Google Scholar 

  2. Andersen, O.M. and Markham, K.R., Flavonoids: Chemistry, Biochemistry and Applications, Boca Raton, FL: Taylor Francis, 2006.

    Google Scholar 

  3. Korul’kin, D.Yu., Abilov, Zh.A., Muzychkina, R.A., and Tolstikov, G.A., Prirodnye flavonoidy (Natural Flavonoids), Novosibirsk: Geo, 2007.

    Google Scholar 

  4. Burlakova, E.B., Ross. Khim. Zh., 2007, vol. 51, no. 1, p. 3.

    CAS  Google Scholar 

  5. Budnikov, H.C. and Ziyatdinova, G.K., J. Anal. Chem., 2005, vol. 60, no. 7, p. 600.

    Article  CAS  Google Scholar 

  6. Tan, W., Lin, L., Li, M., Zhang, Y., Tong, Y., Xiao, D., and Ding, J., Eur. J. Pharm., 2003, vol. 459, nos. 2–3, p. 255.

    CAS  Google Scholar 

  7. Chen, C., Zhou, J., and Ji, C., Life Sci., 2010, vol. 87, p. 333.

    Article  CAS  Google Scholar 

  8. Biesaga, M. and Pyrzynska, K., Crit. Rev. Anal. Chem., 2009, vol. 39, no. 2, p. 95.

    Article  CAS  Google Scholar 

  9. Hollman, P.C.H. and Arts, I.C.W., J. Sci. Food Agric., 2000, vol. 80, p. 1081.

    Article  CAS  Google Scholar 

  10. Murota, K. and Terao, J., Arch. Biochem. Biophys., 2003, vol. 417, p. 12.

    Article  CAS  Google Scholar 

  11. Pinelo, M., Manzocco, L., Nuńez, M.J., and Nicoli, M.C., Food Chem., 2004, vol. 68, no. 1, p. 201.

    Article  CAS  Google Scholar 

  12. Erlund, I., Kosonen, T., Alfihan, G., Mäenpää, J., Perttunen, K., Kenraali, J., Parantainen, J., and Aro, A., Eur. J. Clin. Pharmacol., 2000, vol. 56, p. 545.

    Article  CAS  Google Scholar 

  13. Molnár-Perl, I. and Füzfai, Zs., J. Chromatogr., A, 2005, vol. 1073, nos. 1–2, p. 201.

    Article  CAS  Google Scholar 

  14. Rijke, E., Out, P., Niessen, W.M.A., Ariese, F., Gooijer, C., and Brinkman, U.A.Th., J. Chromatogr., A, 2006, vol. 1112, nos. 1–2, p. 31.

    Article  CAS  Google Scholar 

  15. Pyrzynska, K. and Biesaga, M., Trend. Anal. Chem., 2009, vol. 28, no. 7, p. 893.

    Article  CAS  Google Scholar 

  16. Tura, D. and Robards, K., J. Chromatogr., A, 2002, vol. 975, no. 1, p. 71.

    Article  CAS  Google Scholar 

  17. Naczk, M. and Shahidi, F., J. Chromatogr., A, 2004, vol. 1054, nos. 1–2, p. 95.

    CAS  Google Scholar 

  18. Robards, K., J. Chromatogr., A, 2003, vol. 1000, nos. 1–2, p. 657.

    Article  CAS  Google Scholar 

  19. Kochetova, M.V., Semenistaya, E.N., Larionov, O.G., and Revina, A.A., Usp. Khim., 2007, vol. 76, no. 1, p. 88.

    Google Scholar 

  20. Kartsova, A.A. and Alekseeva, A.V., J. Anal. Chem., 2008, vol. 63, no. 11, p. 1024.

    Article  CAS  Google Scholar 

  21. Wach, A., Pyrzyńska, K., and Biesaga, M., Food Chem., 2007, vol. 100, no. 2, p. 699.

    Article  CAS  Google Scholar 

  22. Williams, F.B., Sander, L.C., Wise, S.A., and Girard, J., J. Chromatogr., A, 2006, vol. 1115, nos. 1–2, p. 93.

    Article  CAS  Google Scholar 

  23. Zhang, S., Dong, S., Chi, L., He, P., Wang, Q., and Fang, Y., Talanta, 2008, vol. 76, no. 4, p. 780.

    Article  CAS  Google Scholar 

  24. Swaroop, A., Gupta, A.P., and Sinha, A.K., Chromatographia, 2005, vol. 62, nos. 11–12, p. 649.

    Article  CAS  Google Scholar 

  25. Zhou, Y.-Z., Liu, X.-X., Zheng, X.-H., and Zheng, J.-B., Chromatographia, 2007, vol. 66, nos. 7–8, p. 635.

    Article  CAS  Google Scholar 

  26. Biesaga, M., Stafiej, A., and Pyrzynska, K., Chromatographia, 2007, vol. 65, nos. 11–12, p. 701.

    Article  CAS  Google Scholar 

  27. Zielińska, D., Nagels, L., and Piskula, M.K., Anal. Chim. Acta, 2008, vol. 617, nos. 1–2, p. 22.

    Article  CAS  Google Scholar 

  28. Chiu, K.-L., Cheng, Y.-C., Chen, J.-H., Chang, C.J., and Yang, P.-W., J. Supercrit. Fluids, 2002, vol. 24, no. 1, p. 77.

    Article  CAS  Google Scholar 

  29. Yang, Y. and Zhang, F., Ultrason. Sonochem., 2008, vol. 15, no. 4, p. 308.

    Article  CAS  Google Scholar 

  30. Fedoseeva, L.M., Kudrikova, L.E., Turchaninov, A.A., and Sivova, Yu.S., Khim. Rast. Syr’ya, 2006, no. 4, p. 49.

  31. Geng, H.-M., Zhang, D.-Q., Zha, J.-P., and Qi, J.-L., Chromatographia, 2007, vol. 66, nos. 3–4, p. 271.

    Article  CAS  Google Scholar 

  32. Pang, N., Malike, D., and Liu, H., Chromatographia, 2009, vol. 70, nos. 7–8, p. 1253.

    Article  CAS  Google Scholar 

  33. Kumar, A., Malik, A.K., and Tewary, Dh.K., Anal. Chim. Acta, 2009, vol. 631, no. 2, pp. 177–181.

    Article  CAS  Google Scholar 

  34. Merken, H.M. and Beecher, G.R., J. Chromatogr., A, 2000, vol. 897, nos. 1–2, p. 177.

    Article  CAS  Google Scholar 

  35. Koh, E., Wimalasiri, K.M.S., Chassy, A.W., and Mitchell, A.E., J. Food Compos. Anal., 2009, vol. 22, nos. 7–8, p. 637.

    Article  CAS  Google Scholar 

  36. Schieber, A., Keller, P., and Carle, R., J. Chromatogr., A, 2001, vol. 910, no. 2, p. 265.

    Article  CAS  Google Scholar 

  37. Sultana, B. and Anwar, F., Food Chem., 2008, vol. 108, p. 879.

    Article  CAS  Google Scholar 

  38. Michodjehoun-Mestres, L., Souquet, J.-M., Fulcrand, H., Bouchut, C., Reynes, M., and Brillouet, J.-M., Food Chem., 2009, vol. 112, no. 4, p. 851.

    Article  CAS  Google Scholar 

  39. Adam, M., Dobiáš, P., Eisner, A., and Ventura, K., J. Sep. Sci., 2009, vol. 32, p. 288.

    Article  CAS  Google Scholar 

  40. Zielińska, D., Wiczkowski, W., and Piskula, M.K., J. Agric. Food Chem., 2008, vol. 56, p. 3524.

    Article  CAS  Google Scholar 

  41. Alonso-Salces, R.M., Barranco, A., Corta, E., Berrueta, L.A., Gallo, B., and Vicente, F., Talanta, 2005, vol. 65, no. 3, p. 654.

    Article  CAS  Google Scholar 

  42. Xu, J., Zhang, H., and Chen, G., Talanta, 2007, vol. 73, no. 5, p. 932.

    Article  CAS  Google Scholar 

  43. Kostić, D.A., Miletić, G.Z., Mitić, S.S., Rašić, I.D., and Živanović, V.V., Chem. Pap., 2007, vol. 61, no. 2, p. 73.

    Article  CAS  Google Scholar 

  44. Kuntić, V., Pejis, N., Mićcić, S., Vucoević, V., Vulić, Z., and Malešev, D., J. Serb. Chem. Soc., 2005, vol. 70, no. 5, p. 753.

    Article  Google Scholar 

  45. Chen, H., Zuo, Y., and Deng, Y., J. Chromatogr., A, 2001, vol. 913, nos. 1–2, p. 387.

    Article  CAS  Google Scholar 

  46. Nuutila, A.M., Kammiovirta, K., and Oksman-Caldentey, K.-M., Food Chem., 2002, vol. 76, p. 519.

    Article  CAS  Google Scholar 

  47. Malovaná, S., Montelongo, F.J.G., Pérez, J.P., and Rodríguez-Delgado, M.A., Anal. Chim. Acta, 2001, vol. 428, no. 2, p. 245.

    Article  Google Scholar 

  48. Rodríguez-Delgado, M.A., Malovaná, S., Pérez, J.P., Borges, T., and Montelongo, F.J.G., J. Chromatogr., A, 2001, vol. 912, no. 2, p. 249.

    Article  Google Scholar 

  49. Swatsitang, P., Tucker, G., Robards, K., and Jardine, D., Anal. Chim. Acta, 2000, vol. 417, no. 2, p. 231.

    Article  CAS  Google Scholar 

  50. Chafer, A., Fornari, T., Berna, A., and Stateva, R.P., J. Supercrit. Fluids, 2004, vol. 32, nos. 1–3, p. 89.

    Article  CAS  Google Scholar 

  51. Señoráns, F.J., Ibañez, E., Cavero, S., Tabera, J., and Reglero, G., J. Chromatogr., A, 2000, vol. 870, nos. 1–2, p. 491.

    Article  Google Scholar 

  52. Wang, S.-P. and Huang, K.-J., J. Chromatogr., A, 2004, vol. 1032, nos. 1–2, p. 273.

    Article  CAS  Google Scholar 

  53. Klejdus, B., Vitamvasova, D., and Kuban, V., Anal. Chim. Acta, 2001, vol. 450, no. 1, p. 81.

    Article  CAS  Google Scholar 

  54. Michalkiewicz, A., Biesaga, M., and Pyrzynska, K., J. Chromatogr., A, 2008, vol. 1187, nos. 1–2, p. 18.

    Article  CAS  Google Scholar 

  55. Korta, E., Bakkali, A., Berruta, L.A., Gallo, B., and Vincente, F., J. Chromatogr., A, 2001, vol. 930, no. 1, p. 21.

    Article  CAS  Google Scholar 

  56. Xia, Y., Guo, T., Zhao, H., Song, M., and Zhang, B., J. Sep. Sci., 2007, vol. 30, p. 1300.

    Article  CAS  Google Scholar 

  57. Ishii, K., Furuta, T., and Kasuya, Y., J. Chromatogr., B, vol. 794, no. 1, p. 49.

  58. Udalova, N.A., Karpov, S.I., Selemenev, V.F., and Sharmar, I.A., Sorbts. Khrom. Prots., 2008, vol. 8, no. 2, p. 304.

    Google Scholar 

  59. Udalova, N.A., Karpov, S.I., Selemenev, V.F., and Sharmar, I.A., Russ. J. Phys. Chem., 2009, vol. 83, no. 6, p. 1006.

    Article  CAS  Google Scholar 

  60. O’Mahony, J., Molinelli, A., Nolan, K., Smyth, M.R., and Mizaikoff, B., Biosens. Bioelectron., 2006, vol. 21, no. 7, p. 1383.

    Article  CAS  Google Scholar 

  61. Xie, J., Zhu, L., Luo, H., Zhou, L., Li, C., and Xu, X., J. Chromatogr., A, 2001, vol. 934, no. 1.

  62. Weiss, R., Molinelli, A., Jakusch, M., and Mizaikoff, B., Bioseparation, 2002, vol. 10, no. 6, p. 379.

    Article  Google Scholar 

  63. Jin, Y.Z. and Row, K.H., Chem. Res. Chin. Univ., 2007, vol. 23, no. 4, p. 412.

    Article  CAS  Google Scholar 

  64. Song, X., Li, J., Wang, J., and Chen, L., Talanta, 2009, vol. 80, no. 2, p. 694.

    Article  CAS  Google Scholar 

  65. Molinelli, A., Weiss, R., and Mizaikoff, B., J. Agric. Food. Chem., 2002, vol. 50, no. 7, p. 1804.

    Article  CAS  Google Scholar 

  66. Theodoridis, G., Lasákova, M., Škerříková, V., Tegou, A., Giantsiou, N., and Jangera, P., J. Sep. Sci., 2006, vol. 29, no. 15, p. 2310.

    Article  CAS  Google Scholar 

  67. Xia, Y.Q., Guo, T.Y., Song, M.D., Zhang, B.H., and Zhang, B.L., React. Func. Polym., 2006, vol. 66, no. 12, p. 1734.

    Article  CAS  Google Scholar 

  68. Xie, J., Chen, L., Luo, H., Li, C., and Xu, X., J. Chromatogr., B, 2003, vol. 788, no. 2, p. 233.

    Article  CAS  Google Scholar 

  69. Kudrinskaya, V.A., Dmitrienko, S.G., and Zolotov, Yu.A., Vestn. Mosk. Univ., Ser. 2: Khim., 2009, vol. 50, no. 3, p. 156.

    CAS  Google Scholar 

  70. Kudrinskaya, V.A. and Dmitrienko, S.G., Sorbts. Khrom. Prots., 2009, vol. 9, no. 6, p. 824.

    Google Scholar 

  71. Pejic, N., Kuntić, V., Vujuc, Z., and Micic, S., Farmaco, 2004, vol. 59, no. 1, p. 21.

    Article  CAS  Google Scholar 

  72. Baranowska, I. and Raróg, D., Talanta, 2001, vol. 55, no. 1, p. 209.

    Article  CAS  Google Scholar 

  73. Malešev, D. and Kuntić, V., J. Serb. Chem. Soc., 2007, vol. 72, no. 10, p. 921.

    Article  CAS  Google Scholar 

  74. Kurzawa, M., Anal. Lett., 2010, vol. 43, p. 993.

    Article  CAS  Google Scholar 

  75. Kudrinskaya, V.A., Dmitrienko, S.G., and Zolotov, Yu.A., Vestn. Mosk. Univ., Ser. 2: Khim., 2010, vol. 51, no. 4, p. 296.

    CAS  Google Scholar 

  76. Kudrinskaya, V.A., Stepanova, A.V., Apyari, V.V., and Dmitrienko, S.G., Abstracts of Papers, S”ezd analitikov Rossii (Congress of the Analytical Chemists of Russia), Moscow, 2010, p. 165.

  77. Matyushina, T.A., Morosanova, E.I., and Zolotov, Yu.A., J. Anal. Chem., 2010, vol. 65, no. 3, p. 308.

    Article  CAS  Google Scholar 

  78. Bel’tyukova, S.V. and Bychkova, A.A., Tr. Odess. Politekh. Univ., 2008, no. 30, p. 242.

  79. Hsiu, S.-L., Tsao, C.-W., Tsai, Y.-C., Ho, H.-J., and Chao, P.-D.L., Biol. Pharm. Bull., 2001, vol. 24, no. 8, p. 967.

    Article  CAS  Google Scholar 

  80. Wang, L. and Morris, M.E., J. Chromatogr., B, 2005, vol. 821, no. 2, p. 194.

    Article  CAS  Google Scholar 

  81. Tarola, A.M. and Giannetti, V., Chromatographia, 2007, vol. 65, nos. 5–6, p. 367.

    Article  CAS  Google Scholar 

  82. Fang, F., Li, J.-M., Pan, Q.-H., and Huang, W.-D., Food Chem., 2007, vol. 101, no. 1, p. 428.

    Article  CAS  Google Scholar 

  83. Castellari, M., Sartini, E., Fabiani, A., Arfelli, G., and Amati, A., J. Chromatogr., A, 2002, vol. 973, nos. 1–2, p. 221.

    Article  CAS  Google Scholar 

  84. Careri, M., Elviri, L., Mangia, A., and Musci, M., J. Chromatogr., A, 2000, vol. 881, nos. 1–2, p. 449.

    Article  CAS  Google Scholar 

  85. Belajova, E. and Suhaj, M., Food Chem., 2004, vol. 86, no. 3, p. 339.

    Article  CAS  Google Scholar 

  86. Peyrat-Maillard, M.N., Bonnely, S., and Berset, C., Talanta, 2000, vol. 51, no. 4, p. 709.

    Article  CAS  Google Scholar 

  87. Wang, F.M., Yao, T.W., and Zeng, S., J. Pharm. Biomed. Anal., 2003, vol. 33, no. 2, p. 317.

    Article  CAS  Google Scholar 

  88. Aguilar-Sánchez, R., Áhuatl-García, F., Dávila-Jiménez, M.M., Elizalde-González, M.P., and Guevara-Villa, M.R.G., J. Pharm. Biomed. Anal., 2005, vol. 38, no. 2, p. 239.

    Article  CAS  Google Scholar 

  89. Martinez-Ortega, M.V., Garsia-Parrila, M.C., and Troncoso, A.M., Anal. Chim. Acta, 2004, vol. 502, no. 1, p. 49.

    Article  CAS  Google Scholar 

  90. Romanova, D., Grancai, D., Jozova, B., and Vachálková, A., J. Chromatogr., A, 2000, vol. 870, nos. 1–2, p. 463.

    Article  CAS  Google Scholar 

  91. Soleas, G.J., Yan, J., and Goldberg, D.M., J. Chromatogr., B, 2001, vol. 757, nos. 1–2, p. 161.

    CAS  Google Scholar 

  92. Wittig, J., Herderich, M., Stewart, E.U., and Crozier, A., J. Chromatogr., B, 2001, vol. 753, nos. 1–2, p. 237.

    CAS  Google Scholar 

  93. Mullen, W., Graf, B.A., Caldwell, S.T., Hartly, R.C., Duthie, G.G., Edwards, C.A., Leon, M.E., and Crozier, A., J. Agric. Food Chem., 2002, vol. 50, no. 12, p. 6902.

    Article  CAS  Google Scholar 

  94. An, D., Zhang, Q., Wub, S., Wei, J., Yang, J., Dong, F., Yan, X., and Guo, C., Food Chem. Toxicol., 2010, vol. 48, p. 1521.

    Article  CAS  Google Scholar 

  95. Cert, A., Moreda, W., and Perez-Camino, M.C., J. Chromatogr., A, 2000, vol. 881, nos. 1–2, p. 131.

    Article  CAS  Google Scholar 

  96. Iurlina, M.O., Saiz, A.I., Fritz, R., and Manrique, G.D., Food Chem., 2009, vol. 115, p. 1141.

    Article  CAS  Google Scholar 

  97. Shui, G. and Leong, L.P., J. Chromatogr., A, 2002, vol. 977, nos. 1–2, p. 89.

    Article  CAS  Google Scholar 

  98. Escarpa, A. and Gonzalez, M.C., Anal. Chim. Acta, 2001, vol. 427, no. 1, p. 119.

    Article  CAS  Google Scholar 

  99. Pérez-Gregorio, R.M., García-Falcón, M.S., Simal-Gándara, J., Rodrigues, A.S., and Almeida, D.P.F., J. Food Compos. Anal., 2010, vol. 23, p. 592.

    Article  CAS  Google Scholar 

  100. Charrouf, Z., Hilali, M., Jauregui, O., Soufiaoui, M., and Guillaume, D., Food Chem., 2007, vol. 100, no. 4, p. 1398.

    Article  CAS  Google Scholar 

  101. Huck, C.W., Buchmeiser, M.R., and Bonn, G.K., J. Chromatogr., A, 2001, vol. 943, no. 1.

  102. Zhang, J., Yang, J., Duan, J., Liang, Z., Zhang, L., Huo, Y., and Zhang, Y., Anal. Chim. Acta, 2005, vol. 532, no. 1, p. 97.

    Article  CAS  Google Scholar 

  103. Vukics, V., Ringer, T., Kery, A., Bonn, G.K., and Guttman, A., J. Chromatogr., A, 2008, vol. 1208, nos. 1–2, p. 11.

    Article  CAS  Google Scholar 

  104. Aguirre-Hernández, E., González-Trujano, M.E., Martínez, A.L., Moreno, J., Kite, G., Terrazas, T., and Soto-Hernández, M., J. Ethnopharmacol., 2010, vol. 127, no. 1, p. 91.

    Article  CAS  Google Scholar 

  105. Spácil, Z., Nováková, L., and Solich, P., Talanta, 2008, vol. 76, no. 1, p. 189.

    Article  CAS  Google Scholar 

  106. Buratti, S., Pellegrini, N., Brenna, O.V., and Mannino, S., J. Agric. Food Chem., 2001, vol. 49, no. 11, p. 5136.

    Article  CAS  Google Scholar 

  107. Yashin, A.Ya., Ross. Khim. Zh., 2008, vol. 52, no. 2, p. 131.

    Google Scholar 

  108. Volpi, N. and Bergonzini, G., J. Pharm. Biomed. Anal., 2006, vol. 42, no. 3, p. 354.

    Article  CAS  Google Scholar 

  109. Cai, Y.-Z., Xing, J., Sun, M., Zhan, Z.-Q., and Corke, H., J. Agric. Food. Chem., 2005, vol. 53, no. 26, p. 9940.

    Article  CAS  Google Scholar 

  110. Prasain, J.K., Wang, C.-C., and Barnes, S., Free Radicals Biol. Med., 2004, vol. 37, no. 9, p. 1324.

    Article  CAS  Google Scholar 

  111. Pohjamo, S.P., Hemming, J.E., Willfor, S.M., Reunanen, M.N.T., and Holmbom, B.R., Phytochemistry, 2003, vol. 63, p. 165.

    Article  CAS  Google Scholar 

  112. Deng, F. and Zito, S.W., J. Chromatogr., A, 2003, vol. 986, nos. 1–2, p. 121.

    Article  CAS  Google Scholar 

  113. Fiamegos, Y.C., Nanos, C.G., Vervoort, J., and Stalikas, C.D., J. Chromatogr., A, 2004, vol. 1041, nos. 1–2, p. 11.

    Article  CAS  Google Scholar 

  114. Canini, A., Alesiani, D., D’Arcangelo, G., and Tagliatesta, P., J. Food. Compos. Anal., 2007, vol. 20, p. 584.

    Article  CAS  Google Scholar 

  115. Füzfai, Zs. and Molnár-Perl, I., J. Chromatogr., A, 2007, vol. 1149, nos. 1–2, p. 88.

    Article  CAS  Google Scholar 

  116. Soleas, G.J., Yan, J., and Goldberg, D.M., J. Chromatogr., B, vol. 757, no. 1, p. 161.

  117. Cimpoiu, C., J. Liq. Chromatogr. Relat. Technol., 2006, vol. 29, nos. 7–8, p. 1125.

    CAS  Google Scholar 

  118. Wollenweber, E., Stevens, J.F., Dorr, M., and Rozefelds, A.C., Phytochemistry, 2003, vol. 62, no. 7, p. 1125.

    Article  CAS  Google Scholar 

  119. Polášek, M., Petriška, I., Pospíšilová, M., and Jahodář, L., Talanta, 2006, vol. 69, no. 1, p. 192.

    Article  CAS  Google Scholar 

  120. Jác, P., Polášek, M., Batista, A.I.V., and Kaderová, L., Electrophoresis, 2008, vol. 29, no. 4, p. 843.

    Article  CAS  Google Scholar 

  121. Sádecká, J. and Polonský, J., J. Chromatogr., A, 2000, vol. 880, nos. 1–2, p. 243.

    Article  Google Scholar 

  122. Xu, X., Ye, H., Wang, W., and Chen, G., J. Agric. Food Chem., 2005, vol. 53, no. 15, p. 5853.

    Article  CAS  Google Scholar 

  123. Arráez-Roman, A., Gómez-Caravaca, A.M., Gómez-Romero, M., Segura-Carretero, A., and Fernández-Gutiėrrez, A., J. Pharm. Biomed. Anal., 2006, vol. 41, p. 1648.

    Article  CAS  Google Scholar 

  124. Volpi, N., Electrophoresis, 2004, vol. 25, 2004, p. 1872.

    Article  CAS  Google Scholar 

  125. Herrero-Martinez, J.M., Oumada, F.Z., Rosės, M., Bosch, E., and Rafols, C., J. Sep. Sci., 2007, vol. 30, p. 2493.

    Article  CAS  Google Scholar 

  126. Chu, Q.C., Fu, L., Guan, Y.Q., and Ye, J., J. Agric. Food Chem., 2004, vol. 52, p. 7828.

    Article  CAS  Google Scholar 

  127. Cao, Y.H., Lou, C.G., Fang, Y.Z., and Ye, J.N., J. Chromatogr., A, 2001, vol. 943, p. 153.

    Article  Google Scholar 

  128. Peng, Y.Y., Liu, F.H., and Ye, J.N., Chromatographia, 2004, vol. 60, p. 597.

    Article  CAS  Google Scholar 

  129. Chen, G., Zhang, H., and Ye, J., Anal. Chim. Acta, 2000, vol. 423, p. 69.

    Article  CAS  Google Scholar 

  130. Yue, M.-E., Jiang, T.-F., and Shi, Y.-P., Talanta, 2004, vol. 62, p. 695.

    Article  CAS  Google Scholar 

  131. Urbonavičiütėa, Jakštas, V., Kornyšova, O., Janulis, V., and Maruška, A., J. Chromatogr., A, 2006, vol. 1112, p. 339.

    Article  CAS  Google Scholar 

  132. Oliveira Brett, A.M. and Ghica, M.-E., Electroanalysis, 2003, vol. 15, p. 1745.

    Article  CAS  Google Scholar 

  133. Ziyatdinova, G.K. and Budnikov, H.C., Khim.-Farm. Zh., 2005, vol. 39, no. 10, p. 54.

    Google Scholar 

  134. Slepchenko, T.B., Anisimova, L.S., Slepchenko, V.F., Mikheeva, E.V., and Pikula, N.P., Khim.-Farm. Zh., 2005, vol. 39, no. 3, p. 54.

    Google Scholar 

  135. Filipiak, M., Anal. Sci., 2001, vol. 17, p. 1667.

    Google Scholar 

  136. Yang, B., Kotani, A., Arai, K., and Kusu, F., Anal. Sci., 2001, vol. 17, p. 599.

    Article  CAS  Google Scholar 

  137. Yang, B., Arai, K., and Kusu, F., Anal. Sci., 2001, vol. 17, p. 987.

    Article  CAS  Google Scholar 

  138. He, J.-B., Lin, X.-Q., and Pan, J., Electroanalysis, 2005, vol. 17, p. 1681.

    Article  CAS  Google Scholar 

  139. Jin, G.-P., He, J.-B., Rui, Z.-B., and Meng, F.-S., Electrochim. Acta, 2006, vol. 51, no. 21, p. 4341.

    Article  CAS  Google Scholar 

  140. Korbut, O., Bucková, M., Labuda, J., and Gründler, P., Sensors, 2003, vol. 3, p. 1.

    Article  CAS  Google Scholar 

  141. Lin, X.-Q., He, J.-B., and Zha, Z.-G., Sens. Actuators, B, 2006, vol. 1, p. 608.

    Article  CAS  Google Scholar 

  142. Adam, V., Mikelova, R., Hubalek, J., Hanustiak, P., Beklova, M., Hodek, P., Horna, A., Trnkova, L., Stiborova, M., Zeman, L., and Kizek, R., Sensors, 2007, vol. 7, p. 2402.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Chemistry, Moscow State University, Moscow, 119992, Russia

    S. G. Dmitrienko, V. A. Kudrinskaya & V. V. Apyari

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  1. S. G. Dmitrienko
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  2. V. A. Kudrinskaya
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  3. V. V. Apyari
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Original Russian Text © S.G. Dmitrienko, V.A. Kudrinskaya, and V.V. Apyari, 2012, published in Zhurnal Analiticheskoi Khimii, 2012, Vol. 67, No. 4, pp. 340–353.

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Dmitrienko, S.G., Kudrinskaya, V.A. & Apyari, V.V. Methods of extraction, preconcentration, and determination of quercetin. J Anal Chem 67, 299–311 (2012). https://doi.org/10.1134/S106193481204003X

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