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Synthesis of Cationic Derivatives of 5,10,15,20-Tetra(4-pyridyl)porphyrin

  • Selected articles originally published in Russian in Rossiiskii Khimicheskii Zhurnal (Russian Chemistry Journal)
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Abstract

New 5,10,15,20-tetra(4-pyridyl)porphyrin- and C6–C9 alkyl bromide-based ionic liquids were synthesized in 23–49% yields. The resulting compounds will be used as key building blocks for creating functional hybrid materials with a defined hydrophilic-hydrophobic balance, which will allow expanding possible applications of useful properties of these compounds. The biological activity of the synthesized porphyrinic ionic liquids was predicted. The cationic porphyrins obtained may be of interest to medicine, specifically in development of drugs for treatment of ischemic heart disease and cerebral palsy. The purity and structure of the synthesized compounds were confirmed by electronic absorption and 1H NMR spectroscopy and mass spectrometry methods.

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ACKNOWLEDGMENTS

We are grateful to T.V. Kustova for assistance in evaluating the biological activity of the synthesized compounds.

This study was carried out using the resources of the Center for Shared Use of Scientific Equipment, Ivanovo State University of Chemistry and Technology (with the support of the Ministry of Science and Higher Education of the Russian Federation, project no. 075-15-2021-671).

Funding

This study was financially supported by the Russian Science Foundation (project no. 22-23-01076).

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Authors and Affiliations

  1. Research Institute of Macroheterocyclic Compounds, Ivanovo State University of Chemistry and Technology, 153000, Ivanovo, Russia

    E. A. Efimova, N. L. Pechnikova, A. V. Lyubimtsev, V. V. Aleksandriiskii & T. A. Ageeva

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  1. E. A. Efimova
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  2. N. L. Pechnikova
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  3. A. V. Lyubimtsev
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  4. V. V. Aleksandriiskii
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  5. T. A. Ageeva
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Correspondence to E. A. Efimova.

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Efimova, E.A., Pechnikova, N.L., Lyubimtsev, A.V. et al. Synthesis of Cationic Derivatives of 5,10,15,20-Tetra(4-pyridyl)porphyrin. Russ J Gen Chem 93, 1574–1578 (2023). https://doi.org/10.1134/S1070363223060300

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  • DOI: https://doi.org/10.1134/S1070363223060300

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