Abstract
We have studied the effects of the benzylating agent character, the reactants ratio, and the solvent nature on the composition of the products of quercetin benzylation. The structure of the products has been confirmed by IR, UV, 1H NMR, 13C NMR, and mass spectra.
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Klyshev, L.K., Bandyukova, V.A., and Alyukina, L.S., Flavonoidy rastenii (Flavonoids of Plants), Alma-Ata: Nauka, 1978.
Lebedeva, T.S. and Sytnik, K.M., Pigmenty rastitel’nogo mira (Pigments of Plora), Kiev: Naukova Dumka, 1986.
Pronchenko, G.E., Lekarstvennye rastitel’nye sredstva (Medicinal Herbal Remedies), Moscow: GYeOTAR-MED, 2002.
Baraboi, V.A., Rastitel’nye fenoly i zdorov’e cheloveka (Plant Phenols and Human Health), Moscow: Nauka, 1984.
Mashkovskii, M.D., Lekarstvennye sredstva (Drugs), Moscow: Novaya Volna, 2000, vol. 2.
Kabiev, O.K. and Balmuhanov, S.B., Prirodnye fenoly — perspektivnyi klass protivoopukholevykh i radiopotentsiruyushchikh soedinenii (Natural Phenols as a Promising Class of Anticancer and Radio Potentiating Compounds), Moscow: Meditsina, 1975.
Rotelli, A.E., Guardia, T., Juarez, A.O., De la Rocha, N.E., and Pelzer, L.E., Pharm. Res., 2003, vol. 48, p. 601. DOI: 10.1016/S1043-6618(03)00225-1.
Murota, K. and Terao, J., Arch. Biochem. Biophys., 2003, vol. 417, p. 12. DOI: 10.1016/S0003-9861(03) 00284-4.
Morikawa, K., Nonaka, M., Narahara, M., Torii, I., Kawaguchi, K., Yoshikawa, T., Kumazawa, Y., and Morikawa, Sh., Life Sci., 2003, vol. 74, p. 709. DOI: 10.1016/j.lfs.2003.06.036.
Ares, J.A. and Qutt, P.E., Curr. Pharm. Design, 1998, vol. 4, p. 17.
Picq, M., Prigent, A.F., Nemoz, G., Andre, A.C., and Pacheco, H., J. Med. Chem., 1982, vol. 25, p. 1192. DOI: 10.1021/jm00352a019.
Matthee, G., Wright, A.D., and Konig, G.M., Planta Med., 1999, vol. 65, p. 493. DOI: 10.1055/s-1999-14004.
Chattopadhyay, D. and Naik, T.N., Mini-Rev. Med. Chem., 2007, vol. 7, p. 275. DOI: 10.2174/1389557077-80059844.
Rao, P.S. and Seshadri, T.R., Proc. Indian Acad. Sci. (A), 1939, vol. 9, p. 177.
Jurd, L., J. Am. Chem. Soc., 1958, vol. 80, p. 5531. DOI: 10.1021/ja01553a054.
Korul’kin, D.Yu., Abilov, Zh.A., Muzychkina, R.A., and Tolstikov, G.A., Prirodnye flavonoidy (Natural Flavonoids), Novosibirsk: Teo, 2007.
Gordon, A.J. and Ford, R.A., The Chemist’s Companion. A Handbook of Practical Data, Techniques and References, New York: Wiley, 1972.
Jurd, L., J. Org. Chem., 1962, vol. 27, p. 1294.
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Original Russian Text © E.R. Karimova, L.V. Spirikhin, L.A. Baltina, M.I. Abdullin, 2014, published in Zhurnal Obshchei Khimii, 2014, Vol. 84, No. 9, pp. 1471–1475.
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Karimova, E.R., Spirikhin, L.V., Baltina, L.A. et al. Synthesis and identification of quercetin benzyl ethers. Russ J Gen Chem 84, 1711–1715 (2014). https://doi.org/10.1134/S1070363214090126
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DOI: https://doi.org/10.1134/S1070363214090126