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Role of Support Receptor Stimulation in Locomotor Training for the Prevention of Hypogravitational Disorders

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Abstract

The time of stimulation of support receptors in locomotor training was analyzed individually for 13 cosmonauts for each day of a long-term space flight. The time of support receptors stimulation with an intensity comparable to that under 1g conditions was shorter compared to Earth conditions. Negative correlation was found between average daily time of support stimulation and the magnitude of changes in the post-flight electromyographic response of soleus muscle to walking. It is proposed to consider the time of support receptors stimulation, along with such parameters as the axial loading and the proportion of the manual mode of treadmill belt movement, as a significant indicator for a personalized approach to the prevention of hypogravitational disorders during long-term space flights.

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ACKNOWLEDGMENTS

The authors express their gratitude to the cosmonauts who took part in the experiment, the staff of Gagarin Cosmonaut Training Center, and crew doctors for the opportunity to conduct pre- and post-flight examinations.

Funding

This study was supported by basic funding from the Russian Academy of Sciences 63.1.

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Authors and Affiliations

  1. Institute of Biomedical Problems, Russian Academy of Sciences, 123007, Moscow, Russia

    E. V. Fomina, N. Yu. Lysova, A. O. Savinkina, R. Yu. Zhedyaev, N. A. Senatorova & T. B. Kukoba

  2. Moscow Pedagogical State University, 119435, Moscow, Russia

    E. V. Fomina & T. B. Kukoba

Authors
  1. E. V. Fomina
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  2. N. Yu. Lysova
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  3. A. O. Savinkina
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  4. R. Yu. Zhedyaev
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  5. N. A. Senatorova
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  6. T. B. Kukoba
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Corresponding authors

Correspondence to E. V. Fomina or R. Yu. Zhedyaev.

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COMPLIANCE WITH ETHICAL STANDARDS

All studies were carried out in accordance with the principles of biomedical ethics formulated in the 1964 Declaration of Helsinki and its later amendments and were approved by the Commission on Biomedical Ethics of the Institute of Biomedical Problems of the Russian Academy of Sciences (Moscow).

CONFLICT OF INTEREST

The authors declare no obvious and potential conflicts of interest related to the publication of this article.

INFORMED CONSENT

All study participants provided their voluntary written informed consent, which they signed after potential risks and benefits, as well as the nature of the upcoming study, were explained to them.

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Translated by K. Lazarev

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Fomina, E.V., Lysova, N.Y., Savinkina, A.O. et al. Role of Support Receptor Stimulation in Locomotor Training for the Prevention of Hypogravitational Disorders. Hum Physiol 47, 320–327 (2021). https://doi.org/10.1134/S0362119721030051

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