Skip to main content
SpringerLink
Log in

Experimental and Theoretical Study of the Raman Spectra of Ganoderic Acid T

  • Published:
Journal of Structural Chemistry Aims and scope Submit manuscript

Abstract

Ganoderic acid T (GAT) has many pharmacological functions such as antitumor and antimycobacterial activity. However, to the best of our knowledge, no commercial high-purity GAT is available and the experimental and theoretical study of the Raman spectrum of GAT has never been reported up to date. Therefore, in this work, we extracted GAT and purified from Ganoderma lucidum mycelia, measured its Raman spectrum and analyzed it based on the density functional theory (DFT) calculation at the B3LYP/6-311+G(d,p) level. The research on the molecular, structural, and spectral properties may provide deeper insights into the functions and better applications of GAT.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. G. Wang, J. Zhao, J. Liu, Y. Huang, J. J. Zhong, and W. Tang. Int. Immunopharmacol., 2007, 7, 864–870.

    Article  CAS  Google Scholar 

  2. S. I. Majagi and P. A. Patil. Pharmacologyonline, 2009, 2, 1038–1047.

    Google Scholar 

  3. X. Y. Guo, D. Liu, M. Ye, J. Han, S. Deng, X. C. Ma, Y. Y. Zhao, B. Zhang, X. Shen, and Q. M. Che. J. Pharm. Biomed. Anal., 2013, 75, 64–73.

    Article  CAS  Google Scholar 

  4. H. M. Kim, S. Y. Paik, K. S. Ra, K. B. Koo, J. W. Yun, and J. W. Choi. J. Microbiol., 2006, 44, 233–242.

    PubMed  CAS  Google Scholar 

  5. O. Handayani, N. Ubaidillah, A. Widya, Vittryaturida, K. Siwi, and D. Sargowo. Eur. Heart J. Suppl., 2017, 19, E35–E35.

    Article  CAS  Google Scholar 

  6. Y. C. Chiang, C. K. Yang, J. C. Shih, and C. N. Lee. Canad. J. Behav. Sci., 2015, 26, 188–189.

    Google Scholar 

  7. U. S. Convention. United States Pharmacopoeia: Ganoderma Lucidum Fruiting Body Powder, 39 Ed., Rockville, 2016.

  8. R. Upton. Standards of Analysis, Quality Control, and Therapeutics. USA, Canada: Santa Cruz, 2000.

    Google Scholar 

  9. T. Kubota, Y. Asaka, I. Miura, and H. Mor. Helv. Chim. Acta, 1982, 65, 611–619.

    Article  CAS  Google Scholar 

  10. Q. Xia, H. Zhang, X. Sun, H. Zhao, L. Wu, D. Zhu, G. Yang, Y. Shao, X. Zhang, and X. Mao. Molecules, 2014, 19, 17478–17535.

    Article  CAS  Google Scholar 

  11. M. Hirotani, C. Ino, T. Furuya, and M. Shiro. Chem. Pharm. Bul., 1986, 34, 2282–2285.

    Article  CAS  Google Scholar 

  12. J. L. Wang, T. Y. Gu, and J. J. Zhong. Biotechnol. Bioeng., 2012, 109, 754–762.

    Article  CAS  Google Scholar 

  13. N. H. Chen and J. J. Zhong. Phytomedicine, 2011, 18, 719–725.

    Article  CAS  Google Scholar 

  14. K. Xu, X. Liang, F. Gao, J. J. Zhong, and J. W. Liu. Process Biochem., 2010, 45, 1261–1267.

    Article  CAS  Google Scholar 

  15. W. Tang, H.W. Liu, W. M. Zhao, D. Z. Wei, and J. J. Zhong. Life Sci., 2006, 80, 205–211.

    Article  CAS  Google Scholar 

  16. M. Isaka, P. Chinthanom, S. Kongthong, K. Srichomthong, and R. Choeyklin. Phytochemistry, 2013, 87, 133–139.

    Article  CAS  Google Scholar 

  17. J. Da, C. R. Cheng, S. Yao, H. L. Long, Y. H. Wang, I. A. Khan, Y. F. Li, Q. R. Wang, L. Y. Cai, and B. H. Jiang. Phytochemistry, 2015, 114, 146–154.

    Article  CAS  Google Scholar 

  18. B. Sylvie, R. David, R. Maryse, G. Barbara, B. Dominique, A. Jeanmarc, and R. Catherinemgc. Food Chemistry, 2009, 113, 1323–1328.

    Article  CAS  Google Scholar 

  19. M. J. Frisch, G. W. Trucks, H. B. Schlegel, G. E. Scuseria, M. A. Robb, J. R. Cheeseman, G. Scalmani, V. Barone, B. Mennucci, G. A. Petersson, H. Nakatsuji, M. Caricato, X. Li, H. P. Hratchian, A. F. Izmaylov, J. Bloino, G. Zheng, J. L. Sonnenberg, M. Hada, M. Ehara, K. Toyota, R. Fukuda, J. Hasegawa, M. Ishida, T. Nakajima, Y. Honda, O. Kitao, H. Nakai, T. Vreven, J. A. Montgomery Jr., J. E. Peralta, F. Ogliaro, M. Bearpark, J. J. Heyd, E. Brothers, K. N. Kudin, V. N. Staroverov, R. Kobayashi, J. Normand, K. Raghavachari, A. Rendell, J. C. Burant, S. S. Iyengar, J. Tomasi, M. Cossi, N. Rega, N. J. Millam, M. Klene, J. E. Knox, J. B. Cross, V. Bakken, C. Adamo, J. Jaramillo, R. Gomperts, R. E. Stratmann, O. Yazyev, A. J. Austin, R. Cammi, C. Pomelli, J. W. Ochterski, R. L. Martin, K. Morokuma, V. G. Zakrzewski, G. A. Voth, P. Salvador, J. J. Dannenberg, S. Dapprich, A. D. Daniels, Ö. Farkas, J. B. Foresman, J. V. Ortiz, J. Cioslowski, and D. J. Fox. Gaussian 09, D. 01. In: Gaussian, Inc., Wallingford CT, 2009.

  20. M. Hirotani, I. Asaka, C. Ino, T. Furuya, and M. Shiro. Phytochemistry, 1987, 26, 2797–2803.

    Article  CAS  Google Scholar 

  21. J. Moellmann and S. Grimme. Phys. Chem. Chem. Phys., 2010, 12, 8500–8504.

    Article  CAS  Google Scholar 

  22. L. Goerigk and S. Grimme. Phys. Chem. Chem. Phys., 2011, 13, 6670–6688.

    Article  CAS  Google Scholar 

  23. A. D. Becke. J. Chem. Phys., 1996, 104, 1040–1046.

    Article  CAS  Google Scholar 

  24. A. D. Becke. J. Chem. Phys., 1993, 98, 5648–5652.

    Article  CAS  Google Scholar 

  25. A. D. Becke. Phys. Rev. A, 1988, 38, 3098–3100.

    Article  CAS  Google Scholar 

  26. C. T. Lee, W. T. Yang, and R. G. Parr. Phys. Rev. B, 1988, 37, 785–789.

    Article  CAS  Google Scholar 

  27. Y. Zhao and D. G. Truhlar. Theor. Chem. Accounts, 2008, 120, 215–241.

    Article  CAS  Google Scholar 

  28. G. H. Yao, Z. M. Zhai, J. Zhong, and Q. Huang. J. Phys. Chem. C, 2017, 121, 9869–9878.

    Article  CAS  Google Scholar 

  29. J. P. Merrick, D. Moran, and L. Radom. J. Phys. Chem. A, 2007, 111, 11683–11700.

    Article  CAS  Google Scholar 

  30. M. L. Laury, M. J. Carlson, and A. K. Wilson. J. Comput. Chem., 2012, 33, 2380–2387.

    Article  CAS  Google Scholar 

  31. M. Muniz-Miranda, C. Gellini, M. Pagliai, M. Innocenti, P. R. Salvi, and V. Schettino. J. Phys. Chem. C, 2010, 114, 13730–13735.

    Article  CAS  Google Scholar 

  32. V. Krishnakumar, G. Keresztury, T. Sundius, and S. Seshadri. Spectrochim. Acta A, 2007, 68, 845–850.

    Article  CAS  Google Scholar 

  33. R. Dennington, T. Keith, and J. Millam. GaussView, Version 5. Semichem Inc., Shawnee Mission, KS, 2009.

Download references

Funding

This work was supported partly by the National Natural Science Foundation of China (Nos. 11475217, 11635013, and 11775272).

Author information

Authors and Affiliations

  1. College of Agriculture, Anhui Science and Technology University, Fengyang, P. R. China

    H. He, Y. Ma & Q. Huang

  2. Institute of Technical Biology and Agriculture Engineering, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, P. R. China

    H. He, G. Yao, Y. Ma & Q. Huang

  3. Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Engineering Research Center of Edible Fungi, Shanghai, P. R. China

    N. Feng & S. Zhou

Authors
  1. H. He
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Yao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Y. Ma
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. N. Feng
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. S. Zhou
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Q. Huang
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

H. He and G. Yao contributed equally to this work.

Corresponding author

Correspondence to Q. Huang.

Additional information

Conflict of Interests

The authors declare that they have no conflict of interests.

Text © The Author(s), 2019, published in Zhurnal Strukturnoi Khimii, 2019, Vol. 60, No. 9, pp. 1467–1480.

Supplementary materials for this article are available for authorized users at doi 10.1134/S0022476619080055.

Supplementary Materials

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

He, H., Yao, G., Ma, Y. et al. Experimental and Theoretical Study of the Raman Spectra of Ganoderic Acid T. J Struct Chem 60, 1407–1415 (2019). https://doi.org/10.1134/S0022476619090051

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0022476619090051

Keywords

Search

Navigation