Abstract
CARNOSINE phosphate was first synthesized by Severin, Georgievskaya and Ivanov1 by a method very similar in detail to that for creatine phosphate2. They showed that this method yields as a rule a diphosphate, both phosphate bonds being high-energy; but that the one which is not on the imidazole ring is more labile. In the presence of muscle extract the latter is transferred to adenosine diphosphate.
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References
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GOODALL, M. Carnosine Phosphate as Phosphate Donor in Muscular Contraction. Nature 178, 539–540 (1956). https://doi.org/10.1038/178539b0
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DOI: https://doi.org/10.1038/178539b0
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