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Structure of Pristimerin

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Abstract

Bhatnagar and Divekar1 described the isolation of an antibiotic, an orange-coloured pigment which they called ‘pristimerin’, from Pristimerae indica and P. grahami (Celastraceae). They found that this compound is particularly active against the viridans group of streptococci. We have been studying the constitution of this complex molecule.

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References

  1. Bhatnagar and Divekar, J. Sci. Indust. Res., 10 B, 56 (1951).

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  2. Karrer and co-workers, Helv. Chim. Acta, 33, 803, 812 (1950). Feiser, J. Amer. Chem. Soc., 48, 2925 (1926).

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  3. Gisvold, J. Amer. Pharm. Soc., 28, 449 (1939); 29, 12 (1940); 31, 529 (1942). Feiser and Jones, J. Amer. Pharm. Soc., 31, 315 (1942). Schechter and Haller, J. Amer. Chem. Soc., 64, 182 (1942).

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KULKARNI, A., SHAH, R. Structure of Pristimerin. Nature 173, 1237–1238 (1954). https://doi.org/10.1038/1731237b0

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