Abstract
Occupational exposure to extremely low-frequency magnetic fields (MF)was studied in 56 male subjects with breast cancer (adenocarcinoma) diagnosedin 1985-91, and 144 subjects with testicular cancer (seminoma andnon-semi-noma), diagnosed in 1985-87. The cases were compared with 1,121control subjects from a previous case-control study on MF and cancer.Exposure assessment was based on the job held longest during the decadebefore diagnosis linked to a job exposure matrix based on MF measurements.The results refer to an estimated average mean of > 0.28 μT (Q4) and> 0.40 μT (P90, part of Q4) with ≤ 0.15 μT (Q1) as reference. Forbreast cancer, the odds ratios (OR) and the 95 percent confidence intervals(CI) were 0.7 (CI = 0.3-1.9) and 0.7 (CI = 0.2-2.3), respectively. For men 60years or younger, the corresponding estimates were OR = 0.9 (CI = 0.2-4.5)and 1.5 (CI = 0.3-8.3). For testicular cancer, the ORs were 1.3 (CI =0.7-2.5) and 2.1 (CI = 1.0-4.3), and for men 40 years or younger the ORs were1.9 (CI = 0.8-4.4) and 3.9 (CI = 1.4-11.2). The results were mainlyattributable to non-seminoma, the more malignant type of testicular cancer.Our conclusion is that the results for male breast cancer, based on limitednumbers, fail to support the suggested association with MF exposure. Theresults for testicular cancer gave some support to the hypothesis of ahormonal link between MFs and cancer, and should be further explored.
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References
Schottenfeld D, Warshauer ME, Sherlock S, Zauber AG, Leder M, Payne R. The epidemiology of testicular cancer in young adults. Am J Epidemiol1980; 112:232–46.
Pearce N, Sheppard RA, Howard JK, Fraser J, Lilley BM. Time trends and occupational differences in cancer of the testis in New Zealand. Cancer 1987; 59:1677–82.
Møller H. Clues to the aetiology of testicular germ cell tumours from descriptive epidemiology. Eur Urol 1993; 23:8–15.
Swerdlow AJ. The epidemiology of testicular cancer. Eur Urol 1993; 23: 35–8.
Forman D, Møller H. Testicular cancer. Cancer Surv 1994; 19/20:323–41.
Casagrande JT, Hanisch R, Pike MC, Ross RK, Brown JB, Henderson BE. A case-control study of male breast cancer. Cancer Res 1988; 48:1326–30.
Olsson H, Ranstam J. Head trauma and exposure to prolactin-elevating drugs as risk factors for male breast cancer. JNCI 1988; 80:679–83.
Lenfant-Pejovic MH, Mlika-Cabanne N, Bouchardy C, Auquier A. Risk factors for male breast cancer: a Franco-Swiss case-control study. Int J Cancer 1990; 45:661–5.
Rosenblatt KA, Thomas DB, McTiernan A, et al. Breast cancer in men: Aspects of familial aggregation. JNCI 1991; 83:849–54.
Moss AR, Osmond D, Bacchetti P, Torti FM, Gurgin V. Hormonal risk factors in testicular cancer. Am J Epidemiol 1986; 124:39–52.
Henderson BE, Benton B, Jing J, Yu MC, Pike MC. Risk factors for cancer of the testis in young men. Int J Cancer 1979; 23:598–602.
Depue RH, Pike MC, Henderson BE. Estrogen exposure during gestation and risk of testicular cancer. JNCI 1983; 71:1151–5.
Forman D, Gallagher R, Møller H, Swerdlow TJ. Aetiology and epidemiology of testicular cancer: report of consensus group. Prog Clin Biol Res 1990; 357.
Thomas DB, Jimenez LM, McTiernan A, et al. Breast cancer in men: Risk factors with hormonal implications. Am J Epidemiol 1992; 135:734–48.
Matanoski GM, Breysse PN, Elliott EA. Electromagnetic field exposure and male breast cancer. Lancet 1991; 337:737.
Demers PA, Thomas DB, Rosenblatt KA, et al. Occupational exposure to electromagnetic fields and breast cancer in men. Am J Epidemiol 1991; 134:340–7.
Tynes T, Andersen A, Langmark F. Incidence of cancer in Norwegian workers potentially exposed to electromagnetic fields. Am J Epidemiol 1992; 136:81–8.
Loomis DP. Cancer of breast among men in electrical occupations. Lancet 1992; 339:1483–4.
Guénel P, Raskmark P, Bach Andersen J, Lynge E. Incidence of cancer in persons with occupational exposure to electromagnetic fields in Denmark. Br J Ind Med 1993; 50:758–64.
Floderus B, Törnqvist S, Stenlund C. Incidence of selected cancers in Swedish railway workers, 1961-79. Cancer Causes Control 1994; 5:189–94.
Rosenbaum PF, Vena JE, Zielezny MA, Michalek AM. Occupational exposure associated with male breast cancer. Am J Epidemiol 1994; 139:30–6.
Thériault G, Goldberg M, Miller AB, et al. Cancer risks associated with occupational exposure to magnetic fields among electric utility workers in Ontario and Quebec, Canada, and France: 1970-1989. Am J Epidemiol 1994; 139:550–72.
Pearce N, Reif J, Fraser J. Case-control studies of cancer in New Zealand electrical workers. Int J Epidemiol 1989; 18:55–9.
Floderus B, Stenlund C, Persson T. Cancer incidence and magnetic field exposure based on a job exposure matrix. Poster Presentation at the 17th Annual Meeting of the Bioelectromagnetics Society (BEMS), Boston, Massachusetts, June, 1995.
Floderus B, Persson T, Stenlund C, Wennberg A, Öst Å, Knave B. Occupational exposure to electromagnetic fields in relation to leukemia and brain tumors: A case-control study in Sweden. Cancer Causes Control 1993; 4:465–76.
World Health Organization. International Classification of Diseases, Seventh Revision. Geneva, Switzerland: WHO, 1976.
Floderus B, Persson T, Stenlund C. Magnetic field exposure in the work place. Reference distribution and exposure in occupational groups. Int J Occup Environ Health 1996; 2:226–38.
Breslow NE, Day NE. Statistical Methods in Cancer Research. Vol 1. The Analysis of Case-control Studies. Lyon, France: International Agency for Research on Cancer, 1980; IARC Sci. Pub. No. 32.
Kheifets LI, Afifi AA, Buffler PA, Zhang ZW. Occupational electric and magnetic field exposure and brain cancer: A meta-analysis. JOEM 1995; 37:1327–41.
Mabuchi K, Bross DS, Kessler II. Risk factors for male breast cancer. JNCI 1985; 74:371–5.
McLaughlin JK, Malker HSR, Blot WJ, Weiner JA, Ericsson JLE, Fraumeni JF Jr. Occupational risks for male breast cancer in Sweden. Br J Ind Med 1988; 45:275–6.
Loomis DP, Savitz DA, Ananth CV. Breast cancer mortality among female electrical workers in the United States. JNCI 1994; 86:921–5.
Coogan PF, Clapp RW, Newcomb PA, et al. Occupational exposure to 60-hertz magnetic fields and risk of breast cancer in women. Epidemiology 1996; 7:459–64.
Verreault R, Weiss NS, Hollenbach KA, Strader CH, Daling JR. Use of electric blankets and risk of testicular cancer. Am J Epidemiol 1990; 131:759–62.
Van Den Eeden SK, Weiss NS, Strader CH, Daling JR. Occupation and the occurrence of testicular cancer. Am J Ind Med 1991; 19:327–37.
Graham S, Gibson R, West D, Swanson M, Burnett W, Dayal H. Epidemiology of cancer of the testis in upstate New York. JNCI 1977; 58:1255–61.
Swerdlow AJ, Douglas AJ, Huttly SRA, Smith PG. Cancer of the testis, socioeconomic status, and occupation. Br J Ind Med 1991; 48:670–4.
Garland FC, Gorham ED, Garland CF, Ducatman AM. Testicular cancer in US Navy personnel. Am J Epidemiol 1988; 127:411–4.
Haughey BP, Graham S, Brasure J, Zielezny M, Sufrin G, Burnett W. The epidemiology of testicular cancer in upstate New York. Am J Epidemiol 1989; 130:25–36.
Lin RS, Kessler II. Epidemiologic findings in testicular cancer. Am J Epidemiol 1979; 110:357.
Stevens RG. Biologically based epidemiological studies of electric power and cancer. Environ Health Perspec Supplements 1993; 101:93–100.
Henderson BE, Ross RK, Pike MC, Casagrande JT. Endogenous hormones as a major factor in human cancer. Cancer Res 1982; 42:3232–9.
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Stenlund, C., Floderus, B. Occupational exposure to magnetic fields in relation to male breast cancer and testicular cancer: a Swedish case-control study. Cancer Causes Control 8, 184–191 (1997). https://doi.org/10.1023/A:1018468112964
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DOI: https://doi.org/10.1023/A:1018468112964