Early Detection of Covid-19 in Canadian Provinces and its Anticipatory Measures for a Medical Emergency

The spread of COVID-19 is incearsing day by day and it has put the entire world and the whole humankind at the stack. The assets of probably the biggest economies are worried because of the enormous infectivity, and transmissibility of this ailment. Because of the developing extent of the number of cases and its ensuing weight on the organization and wellbeing experts, some expectation strategies would be required to anticipate the quantity of evidence in the future. In this paper, we have utilized time series forecasting approach entitled autoregressive integrated moving average, and bend fitting for the forecast of the quantity of COVID-19 cases in Canadian Province for 30 days ahead. The estimates of different parameters (number of positive cases, number of recouped cases, and decrease cases) got by the proposed strategy is exact inside a specific range, and will be a beneficial apparatus for overseers, and wellbeing officials to organize the clinical office in the distinctive Canadian Province.


Introduction
In the unexpected pandemic (Covid-19), every human being is living in a fearful environment, and obviously, it is spreading out rapidly and effected the human's life. In December 2019. All world is confronting a century pandemic Coronavirus, which has been spreading at an extremely high fast speed from the finish of 2019. Presenting in December 2019, right off the bat, it had tainted a Chinese human in Wuhan on 30th January 2020, China [1]. The official declaration of this novel pneumonia episode a "worldwide pandemic" on the eleventh walk by the World Health Organization (WHO) (Wang et al. [1]) and given another name Covid-19. Covid-19 has been moved from creature to human and directly; it is dissipating in all mainlands. The absence of any forestalling antibody demonstrated hazardous to human life. All segments, for example, training, accommodation, transportation, exchanging and so on., and a lot more are not affected by this worldwide pandemic. As of 21st May 2020, out of an aggregate of 4,893,186 affirmed cases, 3,23,256 passings are affirmed in the entire world [2]. A few analysts from the globe have been attempting to foresee Covid-19 cases. Pestilence improvement drifts in South Korea, Italy, and Iran were anticipated utilizing forward expectation and in backward induction [3]. Using bend fitting and repetitive neural system, future Covid-19 positive cases and affirmed cases were distinguished in India [4]. Canada has an aggregate of ten Provinces, and three territories and Covid-19 additionally begin affecting since 30th January 2020 when the main case was seen from Chines inception [5]. The present research study has prime focus on the prediction of Covid-19 cases w.r.t. different parameters such as number of positive cases, number of recouped cases, and decrease cases. The proposed research work will be a beneficial apparatus for overseers, and wellbeing officials to organize the clinical office in the distinctive Canadian Province. The following are the major highlights of the proposed research work: • Expert modeler forecasting has been proposed for COVID-19 in Canadian Provinces. • Thirty days of day-ahead estimation for different parameters has been made. • Analysis of the impact of lockdown, social separation, and effect of change proportion. • Forecasting and an understanding of conceivable circumstances in the coming days have been reported. • Predicting of the relationship of deceased patients with recovered and confirmed patients has been made. • Predicting the decease and confirmed cases in the distinct Provinces.

Literature Review
The epidemic comes into picture at wet market (Wuhan city) in China. The first recognized cases have found some symptoms like problem in the respiratory system, sneezing, dry coughing, and fever. But there was no any proof that this virus spread due to this wet market in Wuhan city [6]. Some researchers also said that this virus can also come due to taking the soup of bats, but it is not proven yet. But after sometime this virus spread slowly in more than 34 provinces in China and 25 other countries resulting in 75,199 confirmed cases and 2009 deaths [7]. Then, the World health organization has given a statement that this virus has a tendency to spread from human to human and also called this disease as Coronavirus (Covid-19) [8]. After increasing the number of patients, China started some action plans against fighting this disease like lockdown in the whole country, sanitized all necessary places, and complete quarantine of every citizen. As on 12th May 2020, the world corona meter showing the total number of cases in China is 82,919, from which 4633 have lost their life and 78,171 have recovered  May 2020. Now a days, this virus has become a massive threat for all over the world. Because there is no proper drugs and vaccine prepared yet, this virus also drops a massive impact on the whole economy of the world, which is continuously decreasing. Coronavirus has a shell, the particles are round or oval, often pleomorphic, and 50-200 nm in diameter as shown in Fig. 1. S-protein lies on the virus surface, creating a rod-shaped structure [9]. As one of the virus' most essential antigenic proteins, the S protein gene is the primary target used for typing. Xu et al. also stated that SARS-CoV-2 S-protein supports a strong association with human angiotensin-converting enzyme 2 (ACE2) molecules, which means that S-protein-ACE2 binding pathway poses a major public health risk to human transmission [10]. Awareness of coronavirus physical and chemical characteristics mainly comes from SARS-CoV and MERS-CoV studies. The coronaviruses are heat-sensitive and can be destroyed for 30 min at 56° C. Besides, the virus can be effectively inactivated by ether, 75% ethanol, chlorine disinfectant, peracetic acid, and chloroform, but not by chlorhexidine [11]. Figure 1 depicts the initial transmission of Covid-19 between profoundly affected regions in the world. Everyday growth rate of affected patients is increasing rapidly. Therefore, keeping this fact in mind, a predictive analysis was performed to estimates the possible count of death of affected patients in Canada. This paper is structured into four sections. Section 1 debated on the introductory theory of Covid-19 with focusing on Canadian impact. Section 2 designed research schema important objectives and relative hypotheses. Section 3 focused on predictive analytical techniques. Section 4 describes the test data under consideration. Section 5 executed experiments with sufficient discussions. Section 6 concluded the major essence of the study.

Proposed Methodology
We used the SPSS expert model for the forecasting of confirmed and decease cases in the Canadian provinces. Based on specific parameters, it spontaneously recognizes and We made the following Eq. (6) of ARIMA model where Y is a dependent variable which is confirmed and Y 1 , Y 2 , ⋯, Y 10 are Canadian provinces, respectively.
The expert model provided the best fit models suggested by ARIMA equation depicted in Table 1.

Test Data Under Consideration
The present study used standard and official data set [12] from 12th May to 31 May 2020. The dataset has five major variables named Province, confirmed, recovered, active, and decease. Except for the Province variable, all variables are scale type. The data set is keeping update at the end of each day, having updated records of ten Province and three territories of Canada. The reliability of data samples is calculated by 0.816 using the Cronbach alpha test. Figure 3 depicts the total number of tested individuals up to 11th May, 2020. Table 2 shows the total number of individually tested versus confirmed cases as on 11 May, 2020. Figure 4 depicts the test data for the total number of individuals tested up to 11 May, 2020 (normal scale) (Fig. 5). Figure 6a, b shows the total number of confirmed cases for covid-19 upto 11th May, 2020 in all the provinces and territories of Canada. Figure 7a-c depicts the total number of decreased cases in all the provinces and territories of Canada.  The number of individuals tested for COVID-19 in Yukon was 1088 as of May 11, 2020. The number of confirmed cases of COVID-19 in Yukon was 11 as of May 11, 2020. The number of deaths related to COVID-19 in Yukon was 0 as of May 11, 2020. Figure 9 depicts the Zone wise total number of decease reported up to 2nd June 2020. and Fig. 11 shows the decease prospects for the next 27 days up to 30 June 2020. Table 3 shows the model fitting for the decrease. Figure 10 shows the expert model's for decease prediction for the next 27 days up to 30 June 2020. One the one hand, the blue lines spot forecast and red curve depict the observed cases in the dataset. The expert model proves the forthcoming human deaths may be reported in the Alberta (around 165), British Columbia (around 180), Ontario (around 2700), Quebec (around 6900), Saskatchewan (around 11), and least chances are found in rest of provinces. Figure 11 visualizes the future deceases count in Canadian provinces. We found four provinces (Alberta, British Columbia, Ontario, and Quebec) where future deaths chances are more and entitled most decease prone zones in Canada. Among the four, the highest predicted decease count is 6922 in Quebec. Hence, the republic of Canada needs to more alert and care about the dangerous conditions ahead. According to results, we put three provinces in the least deceases prone zones depicted left side of the graph. Figure 12 plots date wise status of confirmed cases reported in distinct provinces of Canada. More than 50,000 humans are infected with covid-19 in Manitoba, and Ontario has around 30,000 cases, which is massive count confirmed cases. Less than 10,000 cases are reported in other provinces. Hence, highly red zone provinces are found in Manitoba and Ontario.   Figure 13 shows confirmed predictions for the next 27 days up to 30 June 2020. Around 3000 confirmed cases may be reported in British Columbia, and Ontario may face around 40,000 confirmed cases. Figure 14 displays the predicted count of the number of confirmed cases in the nine provinces. Four provinces are predicted where huge confirmation is seen like Nova Scotia, British Columbia, Ontario, and Quebec. The least prediction counts are observed in the least prospecting confirmed zones. Table 4 shows the model fitting for confirmed cases in all the provinces of Canada, including territories.

Conclusion
This paper presented a predictive model to estimate the future human decease infected with Covid-19 for all the provinces of Canada, including three territories. The findings of the study explored the strong relationship between patient decease rate with recovery and active status. On one hand, active cases impacted the decease rate, and on the other hand, patient deceases are effected by the recovered patient. Following the government Covid-19 guidelines, yet to be enhancement are observed in active, recovered, and decease count. Therefore, highly decease prospects are found in the active and recovered cases. Further, present models alerted red zone states to take precautionary measures from the pandemic (Table 5).  Computer Science, Trnava University, Slovakia, for motivated to write this article and continuous support throughout entire Ph.D study.
Funding Open access funding provided by Eötvös Loránd University.

Complaince with Ethical Standards
Conflict of interest The authors declare that they have no conflict of interest.
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