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Endophthalmitis: Types and Recent Trends in Diagnosis

  • Clinical Pharmacology (L Brunetti, Section Editor)
  • Published:
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Abstract

Purpose of Review

Endophthalmitis is rare but one of the most serious ophthalmic emergencies, which involves inflammation involving vitreous or aqueous fluids. An immediate diagnosis and treatment become crucial for the visual prognosis, which also depends on the causative microorganism. Unless diagnosed and treated promptly, acute endophthalmitis can lead to severe vision loss.

Recent Findings

A large database and several recently published retrospective studies have reported a fall in the rates of endophthalmitis with routine use of antibiotics. Intracameral cefuroxime use resulted in decline of incidence of postoperative endophthalmitis. In many European countries, routine cefuroxime use is quite common, whereas moxifloxacin is most prevalently used in India.

Summary

Lack of clinical suspicion and the empiric use of corticosteroids without proper antimicrobials treatment elevate the risk of momentous loss of vision. Therefore, it is crucial for clinicians to identify endophthalmitis and diagnose it as early as possible for prompt initiation of effective therapy. New controlled trials addressing the treatment of endophthalmitis are highly recommended.

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Authors and Affiliations

  1. Department of Biotechnology, Maharishi Markandeshwar (Deemed To Be) University, Mullana (Ambala), Haryana, India

    Surya Prakash Sharma & Sunil Kumar

  2. Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector-12, Chandigarh, India

    Surya Prakash Sharma & Reema Bansal

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  1. Surya Prakash Sharma
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Correspondence to Sunil Kumar.

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Sharma, S.P., Bansal, R. & Kumar, S. Endophthalmitis: Types and Recent Trends in Diagnosis. Curr Pharmacol Rep 8, 106–111 (2022). https://doi.org/10.1007/s40495-021-00278-1

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