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Comparison of preoperative penile elastographic ultrasound findings and pathological tissue results of patients implemented with penile prosthesis

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Abstract

Objective

Histopathological analysis of the relationship between penile elastography and erectile dysfunction.

Material and method

12 patients who applied to our clinic for erectile dysfunction in the last 1 year and accepted this study were included. Preoperative two-dimensional shear wave elastography imaging was performed in 12 patients and recorded in the Pascal (kPa) unit. Approximately 0.5 × 0.5 × 0.5 cm tissue samples were taken from the right and left cavernous tissue during penile prosthesis implantation operation. Tissue samples were sent to the pathology department. The percentage of the area covered by muscle fibers and elastic fibers in the corpus cavernosum was noted semi-quantitatively (ratio of muscle fibers and cavernous body elastic fiber score). All data obtained were compared with each other.

Results

Cavernous body elastic fiber score data(Grouped Score 1, 2 and 3) and percentage of cavernous body muscle fibers data (Grouped %10, %20, %30… %100) were compared with Shear wave elastography data (kPa). The results were not statistically significant according to the Kruskal Wallis Test. Cavernous body elastic fiber score and the percentage of cavernous body muscle fibers were also compared, it was not statistically significant according to the Kruskal Wallis test and Spearman’s correlation test.

Conclusions

Penile shear wave elastography can be used clinically to quantitatively assess the amount of smooth muscle cells and elastic fibers in the penis, but it deserves to be studied with a larger number of patients and a more specific interpretation of the pathology preparation.

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Acknowledgements

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Authors and Affiliations

  1. Department of Urology, Celal Bayar University Faculty of Medicine, Manisa, Turkey

    Yunus Erol Bozkurt & Bilal H. Gümüş

  2. Department of Radiology, Celal Bayar University Faculty of Medicine, Manisa, Turkey

    Fatih Düzgün

  3. Department of Pathology, Celal Bayar University Faculty of Medicine, Manisa, Turkey

    Nalan Neşe

  4. Department of Urology, Manisa Merkez Efendi State Hospital, Manisa, Turkey

    Yunus Erol Bozkurt

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  1. Yunus Erol Bozkurt
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  2. Bilal H. Gümüş
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Correspondence to Yunus Erol Bozkurt.

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Bozkurt, Y.E., Gümüş, B.H., Düzgün, F. et al. Comparison of preoperative penile elastographic ultrasound findings and pathological tissue results of patients implemented with penile prosthesis. J Ultrasound 26, 99–105 (2023). https://doi.org/10.1007/s40477-022-00705-z

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  • DOI: https://doi.org/10.1007/s40477-022-00705-z

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