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Kontinuierliche subkutane Apomorphin-Gabe bei fortgeschrittener Parkinson-Krankheit

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In einer pivotalen Phase-III-Studie wurde die Wirksamkeit der kontinuierlichen subkutanen Gabe von Apomorphin bei Parkinson-Patienten mit persistierenden motorischen Wirkungsfluktuationen bewiesen.

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Literatur

  1. Kruger R, Klucken J, Weiss D et al. Classification of advanced stages of Parkinson’s disease: translation into stratified treatments. J Neural Transm (Vienna) 2017;124:1015–27

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  2. Katzenschlager R, Poewe W, Rascol O et al. Apomorphine subcutaneous infusion in patients with Parkinson’s disease with persistent motor fluctuations (TOLEDO): a multicentre, double-blind, randomised, placebo-controlled trial. Lancet Neurol 2018;17:749–59

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Tönges, L. Kontinuierliche subkutane Apomorphin-Gabe bei fortgeschrittener Parkinson-Krankheit. DNP 20, 18–19 (2019). https://doi.org/10.1007/s15202-019-2135-6

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  • DOI: https://doi.org/10.1007/s15202-019-2135-6

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