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Allergene von Hausstaub- und Vorratsmilben

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Zusammenfassung

Hausstaubmilben gehören zu den wichtigsten Allergieauslösern weltweit. Während Milben der Gattung Dermatophagoides beinahe weltweit vorkommen, sind die tropische Milbe Blomia tropicalis sowie die Vorratsmilben nur für gewisse Gebiete beziehungsweise Personengruppen von Bedeutung. Die wichtigsten Allergene von Dermatophagoides pteronyssinus sind Der p 1, Der p 2 und Der p 23 mit IgE-Bindungshäufigkeiten von mehr als 70 % und hoher allergener Aktivität. Außerdem von Bedeutung sind Der p 5, Der p 7 und Der p 21, die eine IgE-Bindungshäufigkeit von etwa 30 % aufweisen. Diese sechs Allergene sind nach dem heutigen Wissensstand jene Allergene von klinischer Relevanz, die auch für die Diagnose und Immuntherapie mit Einzelkomponenten benötigt werden.

Zitierweise: Vrtala S. Allergens from house dust and storage mites. Allergo J Int 2022;31:267-71

https://doi.org/10.1007/s40629-022-00226-5

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  1. Medizinische Universität Wien, Institut für Pathophysiologie und Allergieforschung, Währinger Gürtel 18-20, 1090, Wien, Österreich

    Susanne Vrtala

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Die Autorin gibt an, dass keine Interessenkonflikte bestehen. Der Verlag erklärt, dass die inhaltliche Qualität des Beitrags durch zwei unabhängige Gutachten geprüft wurde. Werbung in dieser Zeitschriftenausgabe hat keinen Bezug zur CME-Fortbildung. Der Verlag garantiert, dass die CME-Fortbildung sowie die CME-Fragen frei sind von werblichen Aussagen und keinerlei Produktempfehlungen enthalten. Dies gilt insbesondere für Präparate, die zur Therapie des dargestellten Krankheitsbildes geeignet sind.

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Vrtala, S. Allergene von Hausstaub- und Vorratsmilben. Allergo J 31, 18–24 (2022). https://doi.org/10.1007/s15007-022-5640-4

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