Skip to main content

Advertisement

Log in

Evidence of Hantavirus circulation among municipal street sweepers, southwest of Iran

  • Original Article
  • Published:
VirusDisease Aims and scope Submit manuscript

Abstract

Hantaviruses are rodent-borne zoonosis pathogens that cause hemorrhagic fever with renal syndrome (HFRS) and Hantavirus cardiopulmonary syndrome (HCPS) in humans. Rodents spread the virus via their excretions. The outbreak of Hantaviruses pose a significant public health problem. The epidemiology and history of Hantaviruses in Iran is not clear and regardless of the data from the few available studies, little is known about its epidemiology in this country. Herein, we discuss the prevalence of IgG antibody against Hantavirus serotypes in 385 street sweepers from southwest of Iran. Serum samples were investigated, using Hantavirus Pool 1 "Eurasia" IgG kit and Pool 2 "America" ELISA IgG kit (Euroimmun, Germany) to detect IgG antibodies against Old and New World Hantaviruses. The results showed a specific IgG antibody in two samples (0.5%). Both of seropositive cases had specific IgG antibody against Old World Hantaviruses. The data of the current study along with the previous data, indicate the circulation of Hantaviruses in Iran. Hence, the risk of Hantavirus infection in high-risk groups should be considered as a serious health issue.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Vinh DC, Embil JM. Hantavirus pulmonary syndrome: a concise clinical review. South Med J. 2009;102(6):620–5.

    Article  Google Scholar 

  2. Hepojoki J, et al. Hantavirus structure–molecular interactions behind the scene. J Gen Virol. 2012;93(8):1631–44.

    Article  CAS  Google Scholar 

  3. Xu L, et al. Seroprevalence, cross antigenicity and circulation sphere of bat-borne hantaviruses revealed by serological and antigenic analyses. PLoS Pathog. 2019;15(1):e1007545.

    Article  Google Scholar 

  4. Elgh F, et al. Development of humoral cross-reactivity to the nucleocapsid protein of heterologous hantaviruses in nephropathia epidemica. FEMS Immunol Med Microbiol. 1998;22(4):309–15.

    Article  CAS  Google Scholar 

  5. Avšič-Županc T, Saksida A, Korva M. Hantavirus infections. Clin Microbiol Infect. 2019;21S:e6–16.

    Article  Google Scholar 

  6. Guterres A, de Lemos ERS. Hantaviruses and a neglected environmental determinant. One Health. 2018;5:27–33.

    Article  Google Scholar 

  7. Jonsson CB, Figueiredo LTM, Vapalahti O. A global perspective on hantavirus ecology, epidemiology, and disease. Clin Microbiol Rev. 2010;23(2):412–41.

    Article  CAS  Google Scholar 

  8. Chinikar S, et al. First evidence of Hantavirus in central Iran as an emerging viral disease. Adv Infect Dis. 2014;4(04):173.

    Article  Google Scholar 

  9. Tian H, Stenseth NC. The ecological dynamics of hantavirus diseases: from environmental variability to disease prevention largely based on data from China. PLoS Neglected Trop Dis. 2019;13(2):e0006901.

    Article  Google Scholar 

  10. Escadafal C, et al. Second external quality assurance study for the serological diagnosis of hantaviruses in Europe. PLoS Neglected Trop Dis. 2012;6(4):e1607.

    Article  Google Scholar 

  11. Ardalan M, Chinikar S, Shoja MM. Hemorrhagic Fever with renal syndrome and its history in Iran. Iran J Kidney Dis. 2014;8(6):438–42.

    PubMed  Google Scholar 

  12. Salehi-Vaziri M, et al. Hantavirus infection in Iranian patients suspected to viral hemorrhagic fever. J Med Virol. 2019;91(10):1737–42.

    Article  CAS  Google Scholar 

  13. Oncul O, et al. Hantavirus infection in istanbul, Turkey. Emerg Infect Dis. 2011;17(2):303.

    Article  Google Scholar 

  14. Zhang Y-Z, et al. Hantavirus infections in humans and animals, China. Emerg Infect Dis. 2010;16(8):1195.

    Article  Google Scholar 

  15. Watson DC, et al. Epidemiology of Hantavirus infections in humans: a comprehensive, global overview. Crit Rev Microbiol. 2014;40(3):261–72.

    Article  Google Scholar 

  16. De Oliveira RC, et al. Hantavirus reservoirs: current status with an emphasis on data from Brazil. Viruses. 2014;6(5):1929–73.

    Article  Google Scholar 

  17. Zhou SS, et al. Assessment of a respiratory face mask for capturing air pollutants and pathogens including human influenza and rhinoviruses. J Thorac Dis. 2018;10(3):2059.

    Article  Google Scholar 

  18. Pakdel N, et al. A survey on helminthic infection in mice (Mus musculus) and rats (Rattus norvegicus and Rattus rattus) in Kermanshah, Iran. Veterinary Research Forum. 2013;4(2):105–109.

  19. Meshkekar M, et al. Helminth infections in Rattus ratus and Rattus norvigicus in Tehran Iran. Iran J Parasitol. 2014;9(4):548.

    PubMed  PubMed Central  Google Scholar 

  20. Mostafavi E, et al. Molecular survey of tularemia and plague in small mammals from Iran. Front Cell Infect Microbiol. 2018;8:215.

    Article  Google Scholar 

  21. Mostafavi E, et al. A field study of plague and tularemia in rodents Western Iran. Vector-Borne Zoonotic Dis. 2017;17(4):247–53.

    Article  Google Scholar 

  22. YIĞIT N, et al. The karyotypes of some rodent species (Mammalia: Rodentia) from eastern Turkey and northern Iran with a new record, Microtus schidlovskii Argyropulo, 1933, from eastern Turkey. Turkish J Zool. 2006;30(4):459–64.

    Google Scholar 

Download references

Acknowledgements

The study financially was supported by a grant by Shiraz University of Medical sciences (no. 95-01-01-11863) which assigned to thesis of Maryam Mansurnejadan. The authors wish to thank Mr. H. Argasi at the Research Consultation Center (RCC) of Shiraz University of Medical Sciences for his invaluable assistance in editing this manuscript.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Seyed Younes Hosseini.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Salehi-Vaziri, M., Sarvari, J., Mansurnejadan, M. et al. Evidence of Hantavirus circulation among municipal street sweepers, southwest of Iran. VirusDis. 32, 251–254 (2021). https://doi.org/10.1007/s13337-021-00694-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13337-021-00694-3

Keywords

Navigation