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Clinical Profile and Renal Ultrasound Characteristics of Children With Nutcracker Syndrome in Turkey

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Abstract

Objective

We aimed to evaluate the clinical profile and radiological findings of children with nutcracker syndrome (NCS) and to assess the association between the parameters.

Methods

A retrospective analysis of the clinical, laboratory and radiological parameters of children diagnosed with NCS between January, 2011 and October, 2017 was done.

Results

Of a total of 29 patients [19 girls, 65.5%] with NCS, having a mean (SD) age of 10.8 years, 72.4% had BMI <-2SD. Approximately half of the patients (51.7%) were asymptomatic. Left flank pain was commonest (9/29; 31%) symptom, followed by macroscopic hematuria (4/29; 13.8%). Isolated proteinuria was seen in 9 children. There was no significant difference between the symptomatic and asymptomatic patients in terms of Doppler ultrasonography findings. All patients were followed up conservatively, 5 received enalapril therapy for moderate proteinuria.

Conclusion

NCS should be considered in children, especially with low BMI, presenting with orthostatic proteinuria and hematuria, with or without left flank pain after ruling out the common causes.

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Funding

Funding: None

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Authors and Affiliations

  1. Department of Pediatrics, Ankara Kecioren Training and Research Hospital, Ankara, Turkey

    Edibe Gözde Basaran

  2. Department of Pediatric Nephrology, Baskent University Faculty of Medicine, Ankara, Turkey

    Aysun Çaltik Yilmaz

  3. Department of Radiology, Ankara Kecioren Training and Research Hospital, Ankara, Turkey

    Özlem Güngör

  4. Department of Pediatric Nephrology, Ankara Kecioren Training and Research Hospital, Ankara, Turkey

    Asli Çelebi Tayfur

  5. Gazi University Faculty of Medicine, Ankara, Turkey

    Bahar Büyükkaragöz

Authors
  1. Edibe Gözde Basaran
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  2. Aysun Çaltik Yilmaz
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  3. Özlem Güngör
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  4. Asli Çelebi Tayfur
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  5. Bahar Büyükkaragöz
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Contributions

Contributors: EGB: concept and designed the study and analyzed data; ACY: concept and designed the study and drafted the manuscript; OG: collected the data and helped in data analysis; ACT, BB: conducted behavioral assessments. All authors approved the final version of manuscript, and are accountable for all aspects related to the study.

Corresponding author

Correspondence to Aysun Çaltik Yilmaz.

Ethics declarations

Ethics clearance: Institutional Ethics Committee of Health Science University, Kecioren Training and Research Hospital; No.1540 dated 10/2017.

Competing interests: None stated.

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Basaran, E.G., Yilmaz, A.Ç., Güngör, Ö. et al. Clinical Profile and Renal Ultrasound Characteristics of Children With Nutcracker Syndrome in Turkey. Indian Pediatr 59, 28–30 (2022). https://doi.org/10.1007/s13312-022-2415-7

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  • DOI: https://doi.org/10.1007/s13312-022-2415-7

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