Abstract
Preeclampsia and eclampsia are grave complications of pregnancy responsible for morbidity and mortality. National Eclampsia Registry of the FOGSI has helped in quantifying the magnanimity and also the clinical relevant pointers which can help in improving the health care delivery. Many complex pathogenic mechanisms are now implicated to be responsible for this disease rightfully called the GESTOSIS which means pregnancy going abnormal. Many preventive strategies have been suggested but only a few are scientifically proved to be useful. Early antenatal care, clinical risk assessment, biomarkers, close vigilance, calcium and nutritional supplementation are useful.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Balancing the scales: expanding treatment for pregnant women with life-threatening hypertensive conditions in developing countries. A report on barriers and solutions to treat preeclampsia and eclampsia. EngenderHealth. 2007.
Zenebe W, Hailemariam S, Mirkuzie W. Hypertensive disorders of pregnancy in Jimma University specialized hospital. Ethiop J Health Sci. 2011;21(3):147–54.
Khan KS, Wojdyla D, Say L, et al. WHO analysis of causes of maternal death: a systematic review. Lancet. 2006;367(9516):1066–74.
Chesley LC, Cooper DW. Genetics of hypertension in pregnancy: possible single gene control in eclampsia and preclampsia in the descendants of eclamptic women. Br J Obstet Gynaecol. 1986;93:898–908.
Dekker GA, Sibai BM. Etiology and pathogenesis of preclampsia: current concepts. Am J Obstet Gynecol. 1998;179(5):1359–75.
Brown MA. The physiology of preeclampsia. Clin Exp Pharmacol Physiol. 1995;22:781–91.
Chandiramani M, Shennan A. Hypertensive disorders of pregnancy: a UK-based perspective. Curr Opin Obstet Gynecol. 2008;20:96–101.
Bellamy L, Casas JP, Hingorani AD, et al. Preclampsia and risk of cardiovascular disease and cancer in later life; systematic review and metaanalysis. BMJ. 2007;335:974.
Farag K, Hassan I, Ledger WL. Prediction of pre-eclampsia: can it be achieved? Obstet Gynecol Sur. 2004;59:464–82.
Cnossen JS, Vollebregt KC, de Vrieze N, et al. Accuracy of mean arterial pressure and blood pressure measurements in predicting pre-eclampsia: systematic review and meta-analysis. BMJ. 2008;336:1117.
Anonymous. Report of the national high blood pressure education program working group on high blood pressure in pregnancy. Am J Obstet Gynecol. 2000;183(1):S1–22.
WHO Guidelines Approved by the Guidelines Review Committee. WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia. Geneva: World Health Organization; 2011.
Duley L, Henderson-Smart D, Knight M, et al. Anitplatelet drugs for prevention of pre-eclampsia and its consequences: systematic review. BMJ. 2001;322:329–33.
Askie LM, Henderson-Smart DJ, Stewart LA. Antiplatelet agents for the prevention of preclampsia: a meta-analysis of individual patient data. Lancet. 2007;369:179.
Hofmeyr GJ, Lawrey TA, Atallah AN, et al. Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems. Cochrane Database Syst Rev. 2010;8:CD001059.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Gupte, S., Wagh, G. Preeclampsia–Eclampsia. J Obstet Gynecol India 64, 4–13 (2014). https://doi.org/10.1007/s13224-014-0502-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13224-014-0502-y