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Clinical Outcome of Immediate Loading UV-Photofunctionalized Implants in Patients with Completely Edentulous Mandible, Placed with Guided Surgery

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Abstract

Objectives

The purpose of this study was to evaluate clinical results of immediate loading UV-photofunctionalized dental implants placed using guided surgery in patients with completely edentulous mandible.

Material and Methods

In this study, 58 fully edentulous patients were treated with immediate loading implant-supported mandibular prostheses. All patients underwent a thorough clinical examination according to the generally accepted scheme; qualitative and quantitative parameters of the jaw bones patients were diagnosed with cone beam computerized tomography (CBCT). Surgical templates modeled in the 3 Shape software were made from biocompatible polymeric materials and provided with depth-calibrated drill sleeves for preparing osteotomies using a 3D printer (Stratasys). Before short implant placement, ultraviolet functionalization of implant surfaces was performed by UV Activator YWJ-QSY001 (Foshan, Wenjian Medikal Enstriman) in the device for 20 s. After flapless surgery, implant sockets were prepared with guided surgery and implants were placed through the sleeves of the surgical template tightening torque of 35–45 Ncm. An implant-supported temporary prosthesis made of acrylic resin was installed 6 h after implantation. Final dental prosthetics was performed 2 months after implant placement.

The patients had 128 short (length 5–6 mm, diameters 4,5–5 mm) and 256 implants with length greater than 10 mm in bone segments with sufficient bone parameters. The following parameters were assessed: implant success, prosthetics survival and changes in peri-implant marginal bone loss (MBL).

Results

During a clinical examination, no serious biological or prosthetic complications have been reported. The esthetic result evaluated from patients was excellent. The mean ISQ of short implants was 69.2 ± 8 for primary stability at implant placement and 73.6 ± 4 ISQ after 3 months. The mean of implants with length greater than 10 mm was 71,2ISQ at implant placement, respectively, and 75,6 ISQ after 3 months. After 3 months of prosthetic loading for short implants marginal bone loss (MBL) 0.74 mm, after 1 year of MBL 11.21 mm, after 5 years of MBL 1,37 mm, for implants with length greater than 10 mm after 3 months of MBL 0.72 mm, after 1 year of MBL 1.19 mm and after 5 years of MBL 1.35. There was no statistically significant difference in clinical indices between short and standard implants. After 5 years of follow-up, stable levels of bone tissue around the implants and healthy tissues around the implants were recorded, and postoperative occlusal function was favorable. The success rates of the short implants in maxilla were 95.5%, and the success rates of the short implants in mandible were 98.7%. The success rates of the implants with length greater than 10 mm in maxilla were 97.8%, and the success rates of the implants with length greater than 10 mm in mandible were 98.8%.

Conclusion

Computer-guided implant surgery and immediate loading of UV-photofunctionalized implants in patients with completely edentulous mandible are a predictable and effective method with a minimum rehabilitation period.

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Abbreviations

CT:

Computed tomography

CBCT:

Cone beam computed tomography

3D:

Three-dimensional

CAD:

Computer-aided design

RF:

A resonance frequency analysis

ISQ:

Implant stability quotient

UA:

Ultraviolet functionalization

MBL:

Marginal bone loss

References

  1. Brånemark PI, Hansson BO, Adell R, et al. (1997) Osseointegrated implants in the treatment of the edentulous jaw: Experience from a 10-year period. Scand J Plastic Reconstr Surg. 16:1–132.

  2. Schnitman PA, Wöhrle PS, Rubenstein JE, DaSilva JD, Wang N (1997) Ten-year results for Branemark implants immediately loaded with fixed prostheses at implant placement. Int J Oral nd Maxillofacial Implants 12:495–503

    CAS  Google Scholar 

  3. Harshakumar K et al (2014) Alveolar ridge augmentation using autogenous block bone grafts harvested from mandibular ramus to facilitate implant placement: a case report. Int J Sci Study 2(1):46–50

    Google Scholar 

  4. Levin B (2013) Alveolar ridge augmentation: combining bioresorbable scaolds with osteoinductive bone grafts in atrophic sites. Follow-Up Evol Tech Compend 34(3):178–187

    Google Scholar 

  5. Rachmiel A et al (2017) Vertical alveolar distraction osteogenesis of the atrophic posterior mandible before dental implant insertion. J Oral Maxillofac Surg 75(6):1164–1175

    Article  PubMed  Google Scholar 

  6. Madan Nanjappa et all.Transport Distraction Osteogenesis for Reconstruction of Mandibular Defects”: Our Experience :Journal of Maxillofacial and Oral Surgery.2011;10:93–100

  7. Lorean A (2013) Inferior alveolar nerve transposition and reposition for dental implant placement in edentulous or partially edentulous mandibles: a multicenter retrospective studyInternational. J Oral Maxillofac Surg 42(5):656–659

    Article  CAS  Google Scholar 

  8. Chiapasco M, Zaniboni M (2011) Failures in jaw reconstructive surgery with autogenous onlay bone grafts for pre-implant purposes: incidence, prevention and management of complications. Oral Maxillofac Surg Clin North Am 23(1):1–15

    Article  PubMed  Google Scholar 

  9. Tallarico M, Meloni SM (2017) Retrospective analysis on survival rate, template-related complications, and prevalence of peri-implantitis of 694 anodized implants placed using computer-guided surgery: results between 1 and 10 years of follow-up. Int J Oral Maxillofac Implants 32:1162–1171

    Article  PubMed  Google Scholar 

  10. Storelli S, Caputo A, Palandrani G, Peditto M, Del Fabbro M, Romeo E, Oteri G (2021) Use of narrow-diameter implants in completely edentulous patients as a prosthetic option: a systematic review of the literature. Biomed Res Int 22(1):5571793

    Google Scholar 

  11. Degidi M, Piattelli A, Carinci F (2008) Clinical outcome of narrow diameter implants: a retrospective study of 510 implants. J Periodontol 79(1):49–54

    Article  PubMed  Google Scholar 

  12. Tutak M, Smektała T, Schneider K, Gołębiewska E, Sporniak-Tutak K (2013) Short dental implants in reduced alveolar bone height: a review of the literature. Med Sci Monitor 19:1037

    Article  Google Scholar 

  13. Ramos AH, Cornacchia GM, Nunes E, Cosso MG, de Souza LN, Zenobio EG (2020) Extra short 4mm implants used to rehabilitation of atrophic posterior mandible: a serial case reports. J Clin Exp Dent 12:e519–e522

    Article  PubMed  PubMed Central  Google Scholar 

  14. Anitua E, Pinas L, Orive G (2015) Retrospective study of short and extra-short implants placed in posterior regions: influence of crown to implant ratio on marginal bone loss. Clin Implant Dent Relat Res 17:102–110

    Article  PubMed  Google Scholar 

  15. Annibali S, Cristalli MP, Dell’Aquila D, Bignozzi I, La Monaca G, Pilloni A (2012) Short dental implants: a systematic review. J Dent Res 91:25–32

    Article  CAS  PubMed  Google Scholar 

  16. Srinivasan M, Vazquez L, Rieder P, Moraguez O, Bernard J-P, Belser UC (2014) Survival rates of short (6 mm) micro-rough surface implants: a review of literature and meta-analysis. Clin Oral Implants Res 25:539–545

    Article  PubMed  Google Scholar 

  17. Anitua E, Alkhraist MH, Pinas L, Begona L, Orive G (2014) Implant survival and crestal bone loss around extra-short implants supporting a fixed denture: the effect of crown height space, crown-to-implant ratio, and offset placement of the prosthesis. Int J Oral Maxillofac Implants 29:682–689

    Article  PubMed  Google Scholar 

  18. Esfahrood ZR, Ahmadi L, Karami E, Asghari S (2017) Short dental implants in the posterior maxilla: a review of the literature. J Korean Assoc Oral Maxillofac Surg 43(2):70–76

    Article  PubMed  PubMed Central  Google Scholar 

  19. Menchero-Cantalejo E, Barona-Dorado C, Cantero-Álvarez M, Fernández-Cáliz F, Martínez-González JM (2011) Meta-analysis on the survival of short implants. Med Oral Patol Oral Cir Bucal 16:546-e551

    Article  Google Scholar 

  20. Watanabe H, Saito K, Kokubun K, Sasaki H, Yoshinari M (2012) Change in surface properties of zirconia and initial attachment of osteoblastlike cells with hydrophilic treatment. Dent Mater J 31:806–814

    Article  CAS  PubMed  Google Scholar 

  21. Feller L, Jadwat Y, Khammissa RA, Meyerov R, Schechter I, Lemmer J (2015) Cellular responses evoked by different surface characteristics of intraosseous titanium implants. Biomed Res Int 2015:171945. https://doi.org/10.1155/2015/171945

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Albertini M, Fernandez-Yague M, Lázaro P, Herrero-Climent M, Rios-Santos JV, Bullon P, Gil FJ (2015) Advances in surfaces and osseointegration in implantology. Biomimetic surfaces Med Oral Patol Oral Cir Bucal 20(3):e316-25. https://doi.org/10.4317/medoral.20353

    Article  PubMed  Google Scholar 

  23. Keleher J, Bashant J, Heldt N, Johnson L, Li Y (2002) Photo-catalytic preparation of silver-coated TiO2 particles for antibacterial applications. World J Microbiol Biotechnol 18:133–139

    Article  CAS  Google Scholar 

  24. Aita H, Hori N, Takeuchi M, Suzuki T, Yamada M, Anpo M et al (2009) The effect of ultraviolet functionalization of titanium on integration with bone. Biomaterials 30:1015–1025

    Article  CAS  PubMed  Google Scholar 

  25. Jun JH, Oh KC, Park KH, Jung N, Li J, Moon HS (2021) Improvement of osseointegration by ultraviolet and/or simvastatin treatment on titanium implants with or without bone graft materials. Materials 14(13):3707. https://doi.org/10.3390/ma14133707

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Choi S-H, Ryu J-H, Kwon J-S, Kim J-E, Cha J-Y, Lee K-J, Yu H-S, Choi E-H, Kim K-M, Hwang C-J (2019) Effect of wet storage on the bioactivity of ultraviolet light-and non-thermal atmospheric pressure plasma-treated titanium and zirconia implant surfaces. Mater Sci Eng C 105:110049. https://doi.org/10.1016/j.msec.2019.110049

    Article  CAS  Google Scholar 

  27. Flanagan D (2016) Photofunctionalization of dental implants. J Oral Implantol 42:445–450. https://doi.org/10.1563/aaid-joi-D-15-00145

    Article  PubMed  Google Scholar 

  28. Amorfini L, Storelli S, Romeo E (2011) Rehabilitation of a dentate mandible requiring a full arch rehabilitation, immediate loading of a fixed complete denture on 8 im- plants placed with a bone-supported surgical computer- planned guide: a case report. J Oral Implantol 37:106–113

    Article  PubMed  Google Scholar 

  29. Meloni SM, De Riu G, Pisano M, Cattina G, Tullio A (2010) Implant treatment software planning and guided flap- less surgery with immediate provisional prosthesis delivery in the fully edentulous maxilla: a retrospective analysis of 15 consecutively treated patients. Eur J Oral Implantol 3:245–251

    PubMed  Google Scholar 

  30. Merli M, Bernardelli F, Esposito M (2008) Computer-guided flapless placement of immediately loaded dental implants in the edentulous maxilla: a pilot prospective case series. Eur J Oral Implantol 1:61–69

    PubMed  Google Scholar 

  31. Van Steenberghe D, Glauser R, Blombäck U et al (2005) A computed tomographic scan-derived customized sur- gical template and fixed prosthesis for flapless sur- gery and immediate loading of implants in fully eden- tulous maxillae: a prospective multicenter study. Clin Implant Dent Relat Res 7(1):111–120

    Article  Google Scholar 

  32. Tallarico M, Meloni SM (2017) Retrospective analysis on survival rate, template-related complications, and prevalence of peri-implantitis of 694 anodized im- plants placed using computer-guided surgery: results between 1 and 10 years of follow-up. Int J Oral Maxillofac Implants 32:1162–1171

    Article  PubMed  Google Scholar 

  33. Meloni SM, Tallarico M, Pisano M, Xhanari E, Canullo L (2017) Immediate loading of fixed complete denture prosthesis supported by 4–8 implants placed using guided surgery: a 5-year prospective study on 66 patients with 356 implants. Clin Implant Dent Relat Res 19:195–206

    Article  PubMed  Google Scholar 

  34. Schwarz MS, Rothman SL, Rhodes ML, Chafetz N (1987) Computed tomography, part I: preoperative assessment of the mandible for endosseous implant surgery. Int J Oral Maxillofac Implants 2:137–141

    CAS  PubMed  Google Scholar 

  35. Dhaese J, Van De Velde T, Komiyama A, Hultin M, De Bruyn H (2012) Accuracy and complications using computer- designed stereolithographic surgical guides for oral re- habilitation by means of dental implants: a review of the literature. Clin Implant Dent Relat Res 14:321–335

    Article  PubMed  Google Scholar 

  36. Schneider D, Marquardt P, Zwahlen M, Jung RE (2009) A systematic review on the accuracy and the clinical outcome of computer-guided template-based implant dentistry. Clin Oral Implants Res 20(4):73–86

    Article  PubMed  Google Scholar 

  37. Windmann G, Bale RJ (2006) Accuracy in computer aided implant surgery-a review. Int J Oral Maxillofac Implants 21(2):305–313

    Google Scholar 

  38. Lopes A, Maló P, De Araujo Nobre M, Sanchez-Fernández E (2015) “The NobelGuide All-on-4 treatment concept for rehabilitation of edentulous jaws: a prospective Report on Medium and long term outcomes. Clin Implant Dent Relat Res 17:406–416

    Article  Google Scholar 

  39. Al Yafi F, Camenisch B, Al-Sabbagh M (2019) Is digital guided implant surgery accurate and reliable? Dent Clin N Am 63(3):381–397

    Article  PubMed  Google Scholar 

  40. Marlière DAA et al (2018) Accuracy of computer-guided surgery for dental implant placement in fully edentulous patients: a systematic review. Eur J Dent 12(1):153–160. https://doi.org/10.4103/ejd.ejd_249_17

    Article  PubMed  PubMed Central  Google Scholar 

  41. Hammerle CH, Stone P, Jung RE, Kapos T, Brodala N (2009) Consensus statements and recommended clinical procedures regarding computer-assisted implant dentistry. Int J Oral Maxillofac Implants. 24(l):126–131.

  42. Hakobyan G, Hakobyan D, Samadbin N (2019) Clinical effectiveness of guided implant surgery. J Implant Adv Clin Dent 11(2):6–14

    Google Scholar 

  43. Gallardo YNR et al (2016) Accuracy comparison of guided surgery for dental implants according to the tissue of support: a systematic review and meta-analysis. Clin Oral Implants Res 28(5):1–11

    Google Scholar 

  44. Orenticher G, Horowitz A, Goldsmith D, Delgado-Ruiz R, Abboud M (2014) Cumulative survival rate of implants placed fully guided using CT-guided surgery: a 7-year retrospective study. Compendiu 35:590–598

    Google Scholar 

  45. Colombo M et al (2017) Clinical applications and effectiveness of guided implant surgery: a critical review based on randomized controlled trials. BMC Oral Health 17:150

    Article  PubMed  PubMed Central  Google Scholar 

  46. Gurlek O, Kaval ME, Buduneli N, Nizam N (2019) Extra-short implants in the prosthetic rehabilitation of the posterior maxilla. Aust Dent J 64:353–358

    Article  CAS  PubMed  Google Scholar 

  47. Queiroz TP, Aguiar SC, Margonar R, de Souza Faloni AP, Gruber R, Luvizuto ER (2015) Clinical study on survival rate of short implants placed in the posterior mandibular region: resonance frequency analysis. Clin Oral Implants Res 26:1036–1042

    Article  PubMed  Google Scholar 

  48. Lemos CA, Ferro-Alves ML, Okamoto R, Mendonca MR, Pellizzer EP (2016) Short dental implants versus standard dental implants placed in the posterior jaws: a systematic review and meta-analysis. J Dent 47:8–17

    Article  PubMed  Google Scholar 

  49. Ciabattoni G, Acocella A, Sacco R (2017) Immediately restored full arch-fixed prosthesis on implants placed in both healed and fresh extraction sockets after computer-planned flapless guided surgery. A 3-year follow-up study. Clin Implant Dent Relat Res 19:997–1008

    Article  PubMed  Google Scholar 

  50. Marra R, Acocella A, Rispoli A, Sacco R, Ganz SD, Blasi A (2013) Full-mouth rehabilitation with immediate loading of implants inserted with computer-guided flapless surgery: A 3-year multicenter clinical evaluation with oral health impact profile. Implant Dent 22:444–452

    Article  PubMed  Google Scholar 

  51. Arlin ML (2006) Short dental implants as a treatment option: results from an observational study in a single private practice. Int J Oral Maxillofac Implants 21:769–776

    PubMed  Google Scholar 

  52. Sun HL, Huang C, Wu YR, Shi B (2011) Failure rates of short (≤ 10 mm) dental implants and factors influencing their failure: a systematic review. Int J Oral Maxillofac Implants 26(4):816–825

    PubMed  Google Scholar 

  53. Yadav A, Yadav R, Gupta A, Baranwal A, Bhatnagar A, Singh V (2017) Effect of ultraviolet irradiation on the osseointegration of a titanium alloy with bone. Contemp Clin Dent 8(4):571–578. https://doi.org/10.4103/ccd.ccd_576_17

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  54. Funato A, Yamada M, Ogawa T (2013) Success rate, healing time, and implant stability of photofunctionalized dental implants. Int J Oral Maxillofac Implants 28:1261

    Article  PubMed  Google Scholar 

  55. Suzuki S, Kobayashi H, Ogawa T (2013) Implant stability change and osseointegration speed of immediately loaded photofunctionalized implants. Implant Dent 22:481–490

    Article  PubMed  Google Scholar 

  56. Bada C, Ye Chan L, Kyung CO, Jae Hoon L (2021) Effects of photofunctionalization on early osseointegration of titanium dental implants in the maxillary posterior region: a randomized double-blinded clinical trial. J Implant Dent 7:37

    Article  Google Scholar 

  57. Venezia P, Torsello F, Santomauro V, Dibello V, Cavalcanti R (2019) Full digital workflow for the treatment of an edentulous patient with guided surgery, immediate loading and 3D-printed hybrid prosthesis: The BARI technique 2.0. A case report. Int J Environ Res Public Health 16:5160

    Article  PubMed  PubMed Central  Google Scholar 

  58. Lerner H, Hauschild U, Sader R, Ghanaati S (2020) Complete-arch fixed reconstruction by means of guided surgery and immediate loading: a retrospective clinical study on 12 patients with 1 year of follow-up. BMC Oral Health 20:15

    Article  PubMed  PubMed Central  Google Scholar 

  59. Dierens M, Collaert B, Deschepper E, Browaeys H, Klinge B, DeBruyn H (2009) Patient-centered outcome of immediately loaded implants in the rehabilitation of fully edentulous jaws. Clin Oral Implants Res 20:1070–1077

    Article  PubMed  Google Scholar 

  60. Szmulkler-Monkler S, Piattelli A, Favero GA, Dubruille JH (2000) Considerations preliminary to the application of early and immediate loading protocols in dental implantology. Clin Oral Implants Res 11(1):12–25

    Article  Google Scholar 

  61. Yilmaz B, Seidt JD, McGlumphy EA, Clelland NL (2011) Comparison of strains for splinted and non- splinted screw-retained prosthesis on short implants. Int J Oral Maxillofac Implants 26:1176–1182

    PubMed  Google Scholar 

  62. Van Assche N, Vercruyssen M, Coucke W, Teughels W, Jacobs R, Quirynen M (2012) Accuracy of computer-aided implant placement. Clin Oral Implants Res 23:112–123

    Article  PubMed  Google Scholar 

  63. Kim SY, Ku JK, Kim HS, Yun PY, Kim YK (2018) A retrospective clinical study of single short implants (less than 8 mm) in posterior edentulous areas. J Adv Prosthodont 10(3):191–196

    Article  PubMed  PubMed Central  Google Scholar 

  64. Papaspyridakos P, De Souza A, Vazouras K, Gholami H, Pagni S, Weber H-P (2018) Survival rates of short dental implants (≤6 mm) compared with implants longer than 6 mm in posterior jaw areas: a meta-analysis. Clin Oral Implants Res. https://doi.org/10.1111/clr.13289

    Article  PubMed  Google Scholar 

  65. French D, Nadji N, Larjava H (2015) Survival and success rates of short straumann implants placed in the mandible: a retrospective study with up to 5 year follow-up. Global J Oral Sci 1(1–8):1

    Google Scholar 

  66. Fatimah Assaf, Guilherme Siqueira-Ibelli, Rogério Margonar, Pâmela Letícia Santos, Ana Paula de Souza-Faloni,Thallita Pereira-Queiroz (Survival rates of short dental implants (≤6 mm) compared with implants longer than 6 mm in posterior jaw areas: A meta-analysis) Survival of short dental implants in atrophied jaw: a systematic review. Int J Interdiscip Dent. 13(1)

  67. Monje A, Chan H-L, Jia-Hui F, Suarez F, Galindo-Moreno P, Wang H-L (2013) Are short dental implants effective? A meta-analysis on prospective clinical trials. J Periodontol 84(7):895–904

    Article  PubMed  Google Scholar 

  68. Alvira-González J, Díaz-Campos E, Sánchez-Garcés MA, Gay-Escoda C (2015) Survival of immediately versus delayed loaded short implants: a prospective case series study. Med Oral Patol Oral Cir Bucal 20(4):e480–e488

    Article  PubMed  PubMed Central  Google Scholar 

  69. Medikeri RS, Pereira MA, Waingade M, Navale S (2022) Survival of surface-modified short versus long implants in complete or partially edentulous patients with a follow-up of 1 year or more: a systematic review and meta-analysis. J Periodontal Implant Sci 52(2):e7. https://doi.org/10.5051/jpis.2007340367

    Article  CAS  Google Scholar 

  70. Choi B, Lee YC, Oh KC et al (2021) Effects of photofunctionalization on early osseointegration of titanium dental implants in the maxillary posterior region: a randomized double-blinded clinical trial. Int J Implant Dent 7:37. https://doi.org/10.1186/s40729-021-00318-x

    Article  PubMed  PubMed Central  Google Scholar 

  71. Lee C, Jeong S-M, Yang H-W, Choi B-H (2020) Effect of ultraviolet irradiation on osseointegration of dental implants: a comparative histomorphometric study in canine models. Appl Sci 10:4216. https://doi.org/10.3390/app10124216

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, Yerevan State Medical University After M. Heratsi, Kievyan str. 10 ap. 65, 0028, Yerevan, Armenia

    Naira Ghambaryan, Ashot Jilavyan, Seda Burnazyan & Gagik Hakobyan

  2. Department of Therapeutic Dentistry, Yerevan State Medical University After M. Heratsi, Yerevan, Armenia

    Margarita Khudaverdyan

  3. Department of Postgraduate Education, Yerevan State Medical University After M. Heratsi, Yerevan, Armenia

    Tunyan Gegham

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  1. Naira Ghambaryan
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Ghambaryan, N., Jilavyan, A., Burnazyan, S. et al. Clinical Outcome of Immediate Loading UV-Photofunctionalized Implants in Patients with Completely Edentulous Mandible, Placed with Guided Surgery. J. Maxillofac. Oral Surg. 22 (Suppl 1), 64–75 (2023). https://doi.org/10.1007/s12663-022-01798-z

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