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Survival of Dental Implants on Irradiated Jaws: A Systematic Review and Meta-analysis

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Abstract

Objectives

Dental implants play a significant role in functional rehabilitation of the oral cavity after debilitating jaw surgeries for oral cavity cancers followed by radiotherapy.

Design

The meta-analysis was done using Preferred Reporting Items for Systematic Review (PRISMA) guidelines published from January 1947 till August 2020. Twenty three articles consisting of 1246 participants with 4838 implants were included in our analysis.

Results

The mean age of the included participants was 51.4 years. 2186 and 1685 implants were placed on irradiated and non-irradiated jaws and showed a success rate of 82.47% and 89.37% respectively. Correspondingly, publication bias of p value = 0.2129 and p-value = 0.6525 was found by Egger’s and Begg’s test respectively for pooled data of 16 studies. The implant success rate of 70.4% on maxillary bone and 94.5% were observed on mandibular bone. Timing of implant placement and its influence on survival rate have resulted in a 75.5% survival rate of dental implants when placed primarily in comparison with 87.7% on delayed placement. The waiting interval of 14 months in delayed implant placement has shown better results.

Conclusion

Presence of radiotherapy does not play a significant role in the success rate of dental implants in oral cavity cancers. However, delayed implant placement may have a better chance of survival.

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Abbreviations

GLOBOCON:

The global cancer observatory

OCC:

Oral cavity cancer

PRISMA:

Preferred reporting items for systematic reviews and meta-analyses

PROSPERO:

Prospective register of systematic reviews

MOOSE:

Meta‐analyses of observational studies in epidemiology

NOS:

New castle Ottawa scale

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Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Mumbai, 400001, India

    Prajwalit Prakash Kende, Suleka Ranganath, Jayant Shivaji Landge, Ashish Sarda & Maroti Wadewale

  2. Department of Biostatistics, Tata Memorial Hospital, Mumbai, India

    Akshay Patil

  3. Fortis Hospital, Mulund, Mumbai, 400012, India

    Hitesh R. Singhavi

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Kende, P.P., Ranganath, S., Landge, J.S. et al. Survival of Dental Implants on Irradiated Jaws: A Systematic Review and Meta-analysis. J. Maxillofac. Oral Surg. 21, 787–795 (2022). https://doi.org/10.1007/s12663-022-01686-6

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