Abstract
A new hopane type pentacyclic triterpenoid, 2-hydroxydiplopterol (1) has been isolated from the metabolites produced by the halotolerant fungal strain Aspergillus variecolor B-17. The structure of 1 was determined by spectroscopic methods and single crystal X-Ray diffraction analysis. 2-Hydroxydiplopterol (1) exhibited cytotoxicity against K562 cells with an IC50 value of 22 µM.
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Wang, WL., Liu, PP., Zhang, YP. et al. 2-Hydroxydiplopterol, a new cytotoxic pentacyclic triterpenoid from the halotolerant fungus Aspergillus variecolor B-17. Arch. Pharm. Res. 32, 1211–1214 (2009). https://doi.org/10.1007/s12272-009-1904-8
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DOI: https://doi.org/10.1007/s12272-009-1904-8