Abstract
Bacterial biofilms attached on surfaces of implants cause nosocomial infections. The polysaccharide poly-β(1-6)-N-acetylglucosamine (PNAG) forms the backbone of Staphylococcus biofilms. A target for drugs to treat these infections is the inhibition of biofilm synthesis and stabilization of PNAG. A promising source of inhibitors are macroalgae, because they have many interactions with bacterial biofilm systems. Isolation and characterization of those inhibitors are our research topic.
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Symanowski, F., Hellwig, V., Grünewald, C. et al. Bekämpfung von resistenten Krankenhauskeimen: Inhibition von Biofilmen. Biospektrum 23, 215–217 (2017). https://doi.org/10.1007/s12268-017-0785-5
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DOI: https://doi.org/10.1007/s12268-017-0785-5