Skip to main content

Advertisement

SpringerLink
Log in

Deep Transcranial Magnetic Stimulation as a Potential Approach for Digital Pain Management in Patients with Psychotic Disorder

  • Letter to the Editor
  • Published:
Neuroscience Bulletin Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Data availability

All data generated or analyzed during this study are included in this article and supplementary materials. Further enquiries can be directed to the corresponding author.

References

  1. Zhuo M. Neural mechanisms underlying anxiety-chronic pain interactions. Trends Neurosci 2016, 39: 136–145.

    Article  CAS  Google Scholar 

  2. Peirs C, Seal RP. Neural circuits for pain: Recent advances and current views. Science 2016, 354: 578–584.

    Article  CAS  Google Scholar 

  3. Kummer KK, Mitrić M, Kalpachidou T, Kress M. The medial prefrontal cortex as a central hub for mental comorbidities associated with chronic pain. Int J Mol Sci 2020, 21: 3440.

    Article  CAS  Google Scholar 

  4. Gomez-Tames J, Hamasaka A, Hirata A, Laakso I, Lu M, Ueno S. Group-level analysis of induced electric field in deep brain regions by different TMS coils. Phys Med Biol 2020, 65: 025007.

    Article  Google Scholar 

  5. Kedzior KK, Gellersen HM, Roth Y, Zangen A. Acute reduction in anxiety after deep transcranial magnetic stimulation (DTMS) in unipolar major depression—a systematic review and meta-analysis. Psychiatry Res 2015, 230: 971–974.

    Article  Google Scholar 

  6. Onesti E, Gabriele M, Cambieri C, Ceccanti M, Raccah R, di Stefano G. H-coil repetitive transcranial magnetic stimulation for pain relief in patients with diabetic neuropathy. Eur J Pain 2013, 17: 1347–1356.

    Article  CAS  Google Scholar 

  7. O'Connell NE, Wand BM, Marston L, Spencer S, Desouza LH. Non-invasive brain stimulation techniques for chronic pain. Cochrane Database Syst Rev 2014:CD008208.

  8. Xiao X, Zhang YQ. A new perspective on the anterior cingulate cortex and affective pain. Neurosci Biobehav Rev 2018, 90: 200–211.

    Article  Google Scholar 

  9. Cui HR, Jiang LJ, Wei YY, Li W, Li H, Zhu JJ, et al. Efficacy and safety of repetitive transcranial magnetic stimulation for generalised anxiety disorder: A meta-analysis. Gen Psychiatr 2019, 32: e100051.

    Article  Google Scholar 

  10. Ren D, Li JN, Qiu XT, Wan FP, Wu ZY, Fan BY, et al. Anterior cingulate cortex mediates hyperalgesia and anxiety induced by chronic pancreatitis in rats. Neurosci Bull 2022, 38: 342–358.

    Article  CAS  Google Scholar 

  11. Cirillo G, di Pino G, Capone F, Ranieri F, Florio L, Todisco V, et al. Neurobiological after-effects of non-invasive brain stimulation. Brain Stimul 2017, 10: 1–18.

    Article  CAS  Google Scholar 

  12. Bliss TVP, Collingridge GL, Kaang BK, Zhuo M. Synaptic plasticity in the anterior cingulate cortex in acute and chronic pain. Nat Rev Neurosci 2016, 17: 485–496.

    Article  CAS  Google Scholar 

  13. Oliveira DS, Vélia Ferreira Mendonça L, Sofia Monteiro Sampaio R, Manuel Pereira Dias de Castro-Lopes J, Ribeiro de Azevedo LF. The impact of anxiety and depression on the outcomes of chronic low back pain multidisciplinary pain management-A multicenter prospective cohort study in pain clinics with one-year follow-up. Pain Med 2019, 20: 736–746.

    Article  Google Scholar 

  14. Galhardoni R, da Silva VA, García-Larrea L, Dale C, Baptista AF, Barbosa LM, et al. Insular and anterior cingulate cortex deep stimulation for central neuropathic pain: Disassembling the percept of pain. Neurology 2019, 92: e2165–e2175.

    Google Scholar 

  15. Selingardi PML, de Lima Rodrigues AL, da Silva VA, Fernandes DTRM, Rosí J Jr, Marcolin MA, et al. Long-term deep-TMS does not negatively affect cognitive functions in stroke and spinal cord injury patients with central neuropathic pain. BMC Neurol 2019, 19: 319.

    Article  Google Scholar 

Download references

Acknowledgements

We sincerely acknowledge the contribution of all volunteers and the clinical staff in Anhui Mental Health Center who contributed to data collection. This work was supported by the National Natural Foundation of China (81571326 and 81501153), the Startup Funding of Shanghai Mental Health Center (2017-kyqd-01), Feixiang Personnel Training Program of Shanghai Mental Health Center (2018-FX-02), Shanghai Key Laboratory of Psychotic Disorders (13dz2260500), Natural Science Research Projects in Anhui Universities (KJ2020A0218), Applied Medicine Research Project of Hefei Health Committee (Hwk2020zd0016, AHWJ2021a036) and Funding of Key Research and Development Projects of Anhui Province (2022e07020002).

Author information

Author notes

  1. Peijun Ju and Di Zhao contributed equally to this work.

Authors and Affiliations

  1. Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 201108, China

    Peijun Ju, Di Zhao, Haisu Wu, Beibei Yang, Zhenghui Yi, Tifei Yuan & Jinghong Chen

  2. Shanghai Key Laboratory of Psychotic Disorders, Shanghai, 201108, China

    Peijun Ju

  3. Anhui Clinical Center for Mental and Psychological Diseases, Hefei Fourth People’s Hospital, Hefei, 230022, China

    Cuizhen Zhu

  4. Anhui Mental Health Center, Hefei, 230022, China

    Cuizhen Zhu

  5. Department of Pain Management, HuaDong Hospital Affiliated to Fudan University, Shanghai, 200040, China

    Yongjun Zheng

  6. School of Life Sciences, Westlake Institute for Advanced Study, Westlake University, Hangzhou, 310024, China

    Shiyu Peng

  7. Co-innovation Center of Neuroregeneration, Nantong University, Nantong, 226019, China

    Tifei Yuan

Authors
  1. Peijun Ju
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Di Zhao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Cuizhen Zhu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yongjun Zheng
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Shiyu Peng
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Haisu Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Beibei Yang
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Zhenghui Yi
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Tifei Yuan
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Jinghong Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Zhenghui Yi, Tifei Yuan or Jinghong Chen.

Ethics declarations

Conflict of interest

The authors declare no conflict of interest.

Study approval statement

This study protocol was reviewed and approved by Anhui Mental Health Center, approval number: HSY-IRB-PJ-YN2019023, Chinese Clinical Trial Registry number, [ChiCTR2000029917]. Consent to participate statement: Written informed consent to participate in the study was given by all participants (or their parent/legal guardian where appropriate) and a statement detailing this appears in the Methods section of the manuscript; the original files have been archived.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file 1 (PDF 385 KB)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ju, P., Zhao, D., Zhu, C. et al. Deep Transcranial Magnetic Stimulation as a Potential Approach for Digital Pain Management in Patients with Psychotic Disorder. Neurosci. Bull. 39, 89–93 (2023). https://doi.org/10.1007/s12264-022-00919-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12264-022-00919-5

Search

Navigation