Skip to main content
SpringerLink
Log in

Tannin–Thioctic Acid Network Hydrogels with Antibacterial and Hydrophobic Properties

  • Regular Article
  • Published:
Fibers and Polymers Aims and scope Submit manuscript

Abstract

Making a multifunctional hydrogel-based wound dressing is a long-term research goal. Therefore, it is of great significance to develop an ideal wound dressing with desirable biocompatibility, adhesive property, antibacterial property and simple production. Herein, molecular network crosslinking hydrogels were achieved through the nucleophilic addition of polyphenol-sulfur radical using tannic acid and thioctic acid as matrix. The multifunctional tannic–thioctic acid (TATA) hydrogels with excellent rheological properties were prepared by further modification of antibacterial and hydrophobic properties. The successful cross-linking of the molecules was confirmed by infrared spectroscopy, Raman spectroscopy and energy dispersive X-ray spectroscopy (EDX). Complex hydrogels had certain hydrophobic properties, which can slowly absorb wound tissue fluid and keep the wetness of the wound. In addition, the hydrogel had good rheological, antibacterial and antioxidant properties, and also improved blood clotting effect and biocompatibility. These results indicated that TATA hydrogel had the potential prospect to be used as a novel wound dressing for a wide range of medical applications.

Graphical abstract

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10

Similar content being viewed by others

Data Availability

All the authors state that the data in this paper is will be available.

References

  1. Z. Ahmadian, A. Correia, M. Hasany, P. Figueiredo, F. Dobakhti, M.R. Eskandari, S.H. Hosseini, R. Abiri, S. Khorshid, J. Hirvonen, Adv. Healthc. Mater. 10, 2001122 (2021)

    Article  CAS  Google Scholar 

  2. M.M. Harriott, N. Bhindi, S. Kassis, B. Summitt, G. Perdikis, B.A. Wormer, T.M. Rankin, C. Kaoutzanis, M. Samaha, C. Stratton, Ann. Plas. Surg. 83, 404 (2019)

    Article  CAS  Google Scholar 

  3. J. Kang, J. Hu, R. Karra, A.L. Dickson, V.A. Tornini, G. Nachtrab, M. Gemberling, J.A. Goldman, B.L. Black, K.D. Poss, Nature 532, 201 (2016)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. E.J. Lee, B.K. Huh, S.N. Kim, J.Y. Lee, C.G. Park, A.G. Mikos, Y.B. Choy, Prog. Mater. Sci. 89, 392 (2017)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. R. Yu, H. Zhang, B. Guo, Nano-Micro. Lett. 14, 1 (2022)

    Article  Google Scholar 

  6. Q. Zhang, C. Shi, D. Qu, Y. Long, B.L. Feringa, H. Tian, Sci. Adv. 4, 8192 (2018)

    Article  Google Scholar 

  7. J. Yang, H. Yu, L. Wang, J. Liu, X. Liu, Y. Hong, Y. Huang, S. Ren, Eur. Polym. J. 172, 111241 (2022)

    Article  CAS  Google Scholar 

  8. A. Jayakumar, V.K. Jose, J.M. Lee, Small Methods 4, 1900735 (2020)

    Article  CAS  Google Scholar 

  9. B.P. Lee, S. Konst, Adv. Mater. 26, 3415 (2014)

    Article  CAS  PubMed  Google Scholar 

  10. S. Li, H. Pan, Y. Wang, J. Sun, J. Mater. Chem. A 8, 3667 (2020)

    Article  CAS  Google Scholar 

  11. G.C. Türkoğlu, A.M. Sarıışık, S.Y. Karavana, Int. J. Polymer. Mater. Po 70, 916 (2021)

    Article  Google Scholar 

  12. L. Sun, Y. Huang, Z. Bian, J. Petrosino, Z. Fan, Y. Wang, K.H. Park, T. Yue, M. Schmidt, S. Galster, J. Ma, H. Zhu, M. Zhang, A.C.S. Appl, Mater. Interfaces 8, 2423 (2016)

    Article  CAS  Google Scholar 

  13. S. Lu, X. Zhang, Z. Tang, H. Xiao, M. Zhang, K. Liu, L. Chen, L. Huang, Y. Ni, H. Wu, Chem. Eng. J. 417, 129329 (2021)

    Article  CAS  Google Scholar 

  14. R. Xu, G. Luo, H. Xia, W. He, J. Zhao, B. Liu, J. Tan, J. Zhou, D. Liu, Y. Wang, Z. Yao, R. Zhan, S. Yang, J. Wu, Biomaterials 40, 1 (2015)

    Article  PubMed  Google Scholar 

  15. Y. Li, C. Zhu, D. Fan, R. Fu, P. Ma, Z. Duan, X. Li, H. Lei, L. Chi, Macromol. Biosci. 19, 1800424 (2019)

    Article  Google Scholar 

  16. Z. Jian, H. Wang, M. Liu, S. Chen, Z. Wang, W. Qian, G. Luo, H. Xia, Mater. Sci. Eng. C 111, 110833 (2020)

    Article  CAS  Google Scholar 

  17. C. Zhu, E. Chalmers, L. Chen, Y. Wang, B. Xu, Y. Li, X. Liu, Small 15, 1970189 (2019)

    Article  Google Scholar 

  18. R.C. Srivastava, M.M. Husain, S.K. Hasan, M. Athar, Cancer. Lett. 153, 1 (2000)

    Article  CAS  PubMed  Google Scholar 

  19. Z. Zhang, Y. Sun, Y. Zheng, W. He, Y. Yang, Y. Xie, Z. Feng, K. Qiao, Mater. Sci. Eng. C 106, 110249 (2020)

    Article  CAS  Google Scholar 

  20. Kaczmarek and Beata, Materials 13, 2895 (2020)

    Article  Google Scholar 

  21. D. Santra, K. Sen, Mater. Today. Chem. 18, 100365 (2020)

    Article  CAS  Google Scholar 

  22. A. Fujimoto, T. Masuda, J. Agr. Food Chem. 60, 5142 (2012)

    Article  CAS  Google Scholar 

  23. L. Song, B. Zhang, G. Gao, C. Xiao, G. Li, Eur. Polym. J. 115, 346 (2019)

    Article  CAS  Google Scholar 

  24. Y. Zhang, Y. Chen, X. Shen, J. Hu, J. Jan, Polymer 86, 32 (2016)

    Article  Google Scholar 

  25. X. Shao, X. Yang, Y. Zhou, Q. Xia, Y. Lu, X. Yan, C. Chen, T. Zheng, L. Zhang, Y. Ma, Y. Ma, S. Gao, Soft Matter 18, 2814 (2022)

    Article  CAS  PubMed  Google Scholar 

  26. C. Chen, X. Yang, S. Li, C. Zhang, Y. Ma, Y. Ma, P. Gao, S. Gao, X. Huang, Green Chem. 23, 1794 (2021)

    Article  CAS  Google Scholar 

  27. Z. Liu, C. Zhang, X. Zhang, C. Wang, F. Liu, R. Yuan, H. Wang, Chem. Eng. J. 411, 10 (2021)

    Google Scholar 

  28. R. Ariati, F. Sales, A. Souza, R.A. Lima, J. Ribeiro, Polymers 13, 21 (2021)

    Article  Google Scholar 

  29. S. Kim, H. Hwang, H. Cho, D. Choi, W. Hwang, Chem. Eng. J. 350, 225 (2018)

    Article  CAS  Google Scholar 

  30. T. Takei, R. Yoshihara, S. Danjo, Y. Fukuhara, C. Evans, R. Tomimatsu, Y. Ohzuno, M. Yoshida, Int. J. Biol. Macromol. 149, 140 (2020)

    Article  CAS  PubMed  Google Scholar 

  31. J.H. Cho, J.S. Lee, J. Shin, E.J. Jeon, S. An, Y.S. Choi, S.W. Cho, Adv. Funct. Mater. 28, 1705244 (2018)

    Article  Google Scholar 

  32. X. Tong, X. Qi, R. Mao, W. Pan, M. Zhang, X. Wu, G. Chen, J. Shen, H. Deng, R. Hu, Carbohydr. Polym. 245, 116585 (2020)

    Article  CAS  PubMed  Google Scholar 

  33. S. Yan, H. Shi, L. Song, X. Wang, L. Liu, S. Luan, Y. Yang, J. Yin, A.C.S. Appl, Mater. Interfaces 8, 24471 (2016)

    Article  CAS  Google Scholar 

  34. Y. Xiang, X. Qi, E. Cai, C. Zhang, J. Wang, Y. Lan, H. Deng, J. Shen, R. Hu, Chem. Eng. J. 460, 141852 (2023)

    Article  CAS  Google Scholar 

  35. S. You, Y. Huang, R. Mao, Y. Xiang, E. Cai, Y. Chen, J. Shen, W. Dong, X. Qi, Ind. Crops Prod. 186, 115273 (2022)

    Article  CAS  Google Scholar 

  36. H. Kim, C. Lee, M.H. Kim, J. Kim, Langmuir 28, 11250 (2012)

    Article  CAS  PubMed  Google Scholar 

  37. K.H. Hong, Polym. Bull. 74, 2861 (2017)

    Article  CAS  Google Scholar 

  38. S. Cheng, H. Wang, X. Pan, C. Zhang, K. Zhang, Z. Chen, W. Dong, A. Xie, X. Qi, ACS Appl. Mater. Interfaces. 14, 11144 (2022)

    Article  CAS  PubMed  Google Scholar 

  39. Y. Chen, Y. Zhang, A. Mensaha, D. Li, Q. Wang, Q. Wei, Carbohydr. Polym. 255, 117508 (2021)

    Article  CAS  PubMed  Google Scholar 

  40. G. Dong, H. Liu, X. Yu, X. Zhang, H. Lu, T. Zhou, J. Cao, Nat. Prod. Res. 32, 2225 (2018)

    Article  CAS  PubMed  Google Scholar 

  41. M. Rutnakornpituk, P. Ngamdee, P. Phinyocheep, Carbohydr. Polym. 63, 229 (2006)

    Article  CAS  Google Scholar 

  42. Z. Wang, C. Lopez, A. Hirsa, N. Koratkar, Appl. Phys. Lett. 91, 023105 (2007)

    Article  Google Scholar 

  43. J. De Ruiter, R. Lagraauw, D. Van Den Ende, F. Mugele, Nat. Phys. 11, 48 (2015)

    Article  Google Scholar 

  44. S. Kulkarni, Z. Xia, S. Yu, W. Kiratitanavit, A.B. Morgan, J. Kumar, R. Mosurkal, R. Nagarajan, A.C.S. Appl, Mater. Interfaces 13, 61620 (2021)

    Article  CAS  Google Scholar 

  45. X. Wang, J. Guan, X. Zhuang, Z. Li, S. Huang, J. Yang, C. Liu, F. Li, F. Tian, J. Wu, Z. Shu, Biomacromol 19, 731 (2018)

    Article  Google Scholar 

  46. Y. Wang, M. Yin, Z. Li, Y. Liu, X. Ren, and T. Huang, Colloids Surf., B, 165, 199 (2018).

  47. M. Yin, Y. Wang, Y. Zhang, X. Ren, Y. Qiu, T. Huang, Carbohydr. Polym. 232, 115823 (2020)

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

This work is supported by the Project funded by Jiangsu Province Industry-University-Research Cooperation Project (BY2022893), Jiangsu Province Vocational College Young Teachers Enterprise Practice Training Project (2022QYSJ015), Vice-general project of Science and Technology of Jiangsu province (FZ20220760), Nantong Basic Science Research Program (JCZ2022100), Jiangsu Advanced Textile Engineering Technology Center Funds (XJFZ/2021/10, XJFZ/2021/19), Scientific Planned Projects for Jiangsu College of Engineering and Technology (GYKY/2021/6), Science and Technology Guiding program of China Textile Industry Federation (2022032) and the Opening Project of Key Laboratory of Clean Dyeing and Finishing Technology of Zhejiang Province(QJRZ2109).

Author information

Authors and Affiliations

  1. Key Laboratory of Eco-Textiles of Ministry of Education, College of Textile Science and Engineering, Jiangnan University, Wuxi, 214122, China

    Xinyi Hu, Rong Li, Change Zhou & Zhiguang Li

  2. Key Laboratory of Clean Dyeing and Finishing Technology of Zhejiang Province, Shaoxing University, Shaoxing, 312000, China

    Xinyi Hu

  3. College of Textile and Garment, Jiangsu Advanced Textile Engineering Technology Center, Jiangsu College of Engineering and Technology, Nantong, 226007, China

    Que Kong

Authors
  1. Xinyi Hu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Que Kong
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Rong Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Change Zhou
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Zhiguang Li
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Zhiguang Li.

Ethics declarations

Conflict of Interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (DOCX 1264 KB)

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hu, X., Kong, Q., Li, R. et al. Tannin–Thioctic Acid Network Hydrogels with Antibacterial and Hydrophobic Properties. Fibers Polym 24, 3373–3384 (2023). https://doi.org/10.1007/s12221-023-00329-y

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12221-023-00329-y

Keywords

Search

Navigation