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Extubation failure due to atypical parkinsonism with negligible motor and variable non-motor symptoms associated with a variant of DCTN1

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Fig. 1

Abbreviations

PaCO2:

Arterial carbon dioxide partial pressure

anti-IgLON5 antibodies:

Anti-immunoglobulin-like cell adhesion molecule 5 antibodies

P:

Proband

WT:

Wild type

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Acknowledgements

The authors would like to express their appreciation to Professor Hideshi Kawakami and Dr. Kodai Kume in the Department of Epidemiology, Research Institute for Radiation Biology and Medicine at Hiroshima University for genetical analysis, Professor Takayoshi Shimohata in the Department of Neurology at Gifu University School of Medicine for examining anti-IgLON5 antibodies, and Laboratory Leader Sakae Itoga at Kazusa DNA Research Institute for examining DCTN1 gene.

We also thank for Dr. Masahiro Nakamori, Dr. Shiro Aoki, Dr. Hiroki Ueno, and Dr. Tomohiko Ohshita for their useful contribution.

Funding

There was no targeted funding to report.

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Authors and Affiliations

  1. Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences, 1-2-3 Minami-ku Kasumi, Hiroshima, 734-8551, Japan

    Hidetada Yamada, Shuichiro Neshige, Hiroyuki Morino & Hirofumi Maruyama

Authors
  1. Hidetada Yamada
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  2. Shuichiro Neshige
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  3. Hiroyuki Morino
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  4. Hirofumi Maruyama
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Corresponding author

Correspondence to Shuichiro Neshige.

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The authors have no conflicts of interest to report.

Human and animal rights

This was a retrospective observational single case report, which did not require Institutional Review Board approval at our institution; however, written informed consent was obtained from the patient and his family. All the procedures involving human participants reported herein were performed in accordance with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

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Written informed consent was obtained from the patient for the publication of the case report.

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Yamada, H., Neshige, S., Morino, H. et al. Extubation failure due to atypical parkinsonism with negligible motor and variable non-motor symptoms associated with a variant of DCTN1. Intern Emerg Med 18, 329–331 (2023). https://doi.org/10.1007/s11739-022-03105-7

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  • DOI: https://doi.org/10.1007/s11739-022-03105-7

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