Skip to main content
Log in

Safety and surgical outcomes of single-port trans-axillary robot-assisted thyroidectomy: Experience from a consecutive series of 300 patients

  • Research
  • Published:
Journal of Robotic Surgery Aims and scope Submit manuscript

Abstract

Since the introduction of the single-port (SP) robotic system, SP trans-axillary robot-assisted thyroidectomy (SP-TART) has been performed. We aimed to evaluate the safety and surgical outcomes of SP-TART in a consecutive series of 300 cases. We analyzed 300 patients with thyroid disease who underwent SP-TART from October 2021 to May 2023 in St. Mary’s Hospital in Seoul, Korea. We analyzed the patients’ clinicopathological characteristics and perioperative outcomes according to surgical extent. Of the 300 cases analyzed, 250 patients underwent less than total thyroidectomy (LTT), 31 patients underwent total thyroidectomy (TT), and 19 patients underwent TT with modified radical neck dissection (TT c mRND). The mean operative times for LTT, TT, and for TT c mRND were 69.8 ± 23.6, 104.2 ± 30.7, and 223.7 ± 72.4 min, respectively. Complications, including postoperative bleeding, transient hypoparathyroidism, and vocal cord palsy, were observed in nine, six, and six LTT, TT, and TT c mRND cases. The SP-TART method is a safe and feasible surgical option with a short operative time, good surgical outcome, and excellent cosmetic results.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

Data availability statement

The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.

References

  1. Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, Pacini F, Randolph GW, Sawka AM, Schlumberger M, Schuff KG (2016) 2015 American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid 26(1):1–133

    Article  PubMed  PubMed Central  Google Scholar 

  2. LeClair K, Bell KJ, Furuya-Kanamori L, Doi SA, Francis DO, Davies L (2021) Evaluation of gender inequity in thyroid cancer diagnosis: differences by sex in US thyroid cancer incidence compared with a meta-analysis of subclinical thyroid cancer rates at autopsy. JAMA Int Med 181(10):1351–1358

    Article  Google Scholar 

  3. Choi Y, Lee JH, Kim YH, Lee YS, Chang HS, Park CS, Roh MR (2014) Impact of postthyroidectomy scar on the quality of life of thyroid cancer patients. Ann Dermatol 26(6):693–699

    Article  PubMed  PubMed Central  Google Scholar 

  4. Tae K, Ji YB, Song CM, Ryu J (2019) Robotic and endoscopic thyroid surgery: evolution and advances. Clin Exp Otorhinolaryngol 12(1):1

    Article  PubMed  Google Scholar 

  5. Chang EH, Kim HY, Koh YW, Chung WY (2017) Overview of robotic thyroidectomy. Gland Surg 6(3):218

    Article  PubMed  PubMed Central  Google Scholar 

  6. de Vries LH, Aykan D, Lodewijk L, Damen JA, Borel Rinkes IH, Vriens MR (2021) Outcomes of minimally invasive thyroid surgery—a systematic review and meta-analysis. Front Endocrinol 12:719397

    Article  Google Scholar 

  7. Pan JH, Zhou H, Zhao XX, Ding H, Wei L, Qin L, Pan YL (2017) Robotic thyroidectomy versus conventional open thyroidectomy for thyroid cancer: a systematic review and meta-analysis. Surg Endosc 31(10):3985–4001

    Article  PubMed  Google Scholar 

  8. Sun GH, Peress L, Pynnonen MA (2014) Systematic review and meta-analysis of robotic vs conventional thyroidectomy approaches for thyroid disease. Otolaryngol Head Neck Surg 150(4):520–32

    Article  PubMed  Google Scholar 

  9. Bhettani MK, Rehman M, Ahmed M, Altaf HN, Choudry UK, Khan KH (2019) Role of pre-operative vitamin D supplementation to reduce post-thyroidectomy hypocalcemia; Cohort study. Int J Surg (London, England) 71:85–90

    Article  Google Scholar 

  10. Amin MB, Edge S, Greene F, Byrd DR, Brookland RK, Washington MK, Gershenwald JE, Compton CC, Hess KR, Sullivan DC, Jessup JM, Brierley JD, Gaspar LE, Schilsky RL, Balch CM, Winchester DP, Asare EA, Madera M, Gress DM, Meyer LR (2017) AJCC cancer staging manual, 8th edn. Springer, New York

  11. Kang IK, Park J, Bae JS, Kim JS, Kim K (2022) Safety and feasibility of single-port trans-axillary robotic thyroidectomy: experience through consecutive 100 cases. Medicina (Kaunas, Lithuania) 58(10):1485

    Google Scholar 

  12. Park J, Kang LK, Kim K, Bae JS, Kim JS (2023) The learning curve for single-port transaxillary robotic thyroidectomy (SP-TART): experience through initial 50 cases of lobectomy. Updates Surg 75(3):691–700

    Article  PubMed  Google Scholar 

  13. Ikeda Y, Takami H, Sasaki Y, Kan S, Niimi M (2000) Endoscopic neck surgery by the axillary approach. J Am College Surg 191(3):336–340

    Article  CAS  Google Scholar 

  14. Kang SW, Jeong JJ, Yun JS, Sung TY, Lee SC, Lee YS, Nam KH, Chang HS, Chung WY, Park CS (2009) Gasless endoscopic thyroidectomy using trans-axillary approach; surgical outcome of 581 patients. Endocr J 56(3):361–369

    Article  PubMed  Google Scholar 

  15. Lombardi CP, Raffaelli M, Princi P, De Crea C, Bellantone R (2006) Video-assisted thyroidectomy: report on the experience of a single center in more than four hundred cases. World J Surg 30(5):794–800

    Article  PubMed  Google Scholar 

  16. Li T, Zhang Z, Chen W, Yu S, Sun B, Deng X, Ge J, Wei Z, Lei S, Li G (2022) Comparison of quality of life and cosmetic result between open and transaxillary endoscopic thyroid lobectomy for papillary thyroid microcarcinoma survivors: a single-center prospective cohort study. Cancer Med 11(22):4146–4156

    Article  PubMed  PubMed Central  Google Scholar 

  17. Lobe TE, Wright SK, Irish MS (2005) Novel uses of surgical robotics in head and neck surgery. J Laparoendosc Adv Surg Tech A 15(6):647–652

    Article  PubMed  Google Scholar 

  18. Kang SW, Jeong JJ, Yun JS, Sung TY, Lee SC, Lee YS, Nam KH, Chang HS, Chung WY, Park CS (2009) Robot-assisted endoscopic surgery for thyroid cancer: experience with the first 100 patients. Surg Endosc 23(11):2399–2406

    Article  PubMed  Google Scholar 

  19. Lee J, Nah KY, Kim RM, Ahn YH, Soh EY, Chung WY (2010) Differences in postoperative outcomes, function, and cosmesis: open versus robotic thyroidectomy. Surg Endosc 24(12):3186–3194

    Article  PubMed  Google Scholar 

  20. Kim JK, Choi SH, Choi SM, Choi HR, Lee CR, Kang SW, Jeong JJ, Nam KH, Chung WY (2022) Single-port transaxillary robotic thyroidectomy (START): 200-cases with two-step retraction method. Surg Endosc 36(4):2688–2696

    Article  PubMed  Google Scholar 

  21. Chang YW, Lee HY, Kim WY, Kim HY, Lee JB, Son GS (2021) Detailed comparison of the da Vinci Xi and S surgical systems for transaxillary thyroidectomy. Medicine 100(3)

  22. Piccoli M, Mullineris B, Gozzo D, Colli G, Pecchini F, Nigro C, Rochira V (2019) Evolution strategies in transaxillary robotic thyroidectomy: considerations on the first 449 cases performed. J Laparoendosc Adv Surg Tech A 29(4):433–440

    Article  PubMed  PubMed Central  Google Scholar 

  23. Ban EJ, Yoo JY, Kim WW, Son HY, Park S, Lee SH, Lee CR, Kang SW, Jeong JJ, Nam KH, Chung WY (2014) Surgical complications after robotic thyroidectomy for thyroid carcinoma: a single center experience with 3,000 patients. Surg Endosc 28(9):2555–2563

    Article  PubMed  Google Scholar 

  24. Lee J, Kwon IS, Bae EH, Chung WY (2013) Comparative analysis of oncological outcomes and quality of life after robotic versus conventional open thyroidectomy with modified radical neck dissection in patients with papillary thyroid carcinoma and lateral neck node metastases. J Clin Endocrinol Metab 98(7):2701–2708

    Article  CAS  PubMed  Google Scholar 

  25. Noureldine SI, Jackson NR, Tufano RP, Kandil E (2013) A comparative North American experience of robotic thyroidectomy in a thyroid cancer population. Langenbeck’s Arch Surg 398(8):1069–1074

    Article  Google Scholar 

  26. Ji KS, Oyekunle TO, Thomas SM, Scheri R, Stang M, Roman SA, Sosa JA (2019) Adequacy of lymph node yield for papillary thyroid cancer: an analysis of 23,131 patients. J Surg Res 244:566–573

    Article  PubMed  Google Scholar 

  27. Beal SH, Chen SL, Schneider PD, Martinez SR (2010) An evaluation of lymph node yield and lymph node ratio in well-differentiated thyroid carcinoma. Am Surg 76(1):28–32

    Article  PubMed  Google Scholar 

  28. Yu ST, Ge JN, Sun BH, Wei ZG, Xiao ZZ, Zhang ZC, Chen WS, Li TT, Lei ST (2021) Lymph node yield in the initial central neck dissection (CND) associated with the risk of recurrence in papillary thyroid cancer: a reoperative CND cohort study. Oral Oncol 123:105567

    Article  PubMed  Google Scholar 

  29. Issa K, Stevens MN, Sun Y, Thomas S, Collins A, Cohen J, Esclamado RM, Rocke DJ (2022) A retrospective study of lymph node yield in lateral neck dissection for papillary thyroid carcinoma. Ear Nose Throat J 101(7):456–462

    Article  PubMed  Google Scholar 

  30. Chung EJ, Cho SJ, Park MW, Rho YS (2019) The impact of the number of harvested central lymph nodes on the lymph node ratio. Auris Nasus Larynx 46(2):267–271

    Article  PubMed  Google Scholar 

  31. Feng JW, Yang XH, Wu BQ, Sun DL, Jiang Y, Qu Z (2019) Predictive factors for central lymph node and lateral cervical lymph node metastases in papillary thyroid carcinoma. Clin Transl Oncol 21(11):1483–1491

    Article  Google Scholar 

  32. Kang SW, Kim MJ, Chung WY (2018) Gasless, transaxillary robotic neck dissection: the technique and evidence. Gland Surg 7(5):466

    Article  PubMed  PubMed Central  Google Scholar 

  33. Ho J, Kim D, Lee JE, Kim JK, Lee CR, Kang SW, Jeong JJ, Nam KH, Chung WY (2023) Single-port transaxillary robotic modified radical neck dissection (STAR-RND): initial experiences. Laryngosc 133(3):709–7014

    Article  Google Scholar 

  34. Holsinger FC, Chung WY (2014) Robotic thyroidectomy. Otolaryngol Clin N Am 47(3):373–378

    Article  Google Scholar 

  35. Yap Z, Kim WW, Kang SW, Lee CR, Lee J, Jeong JJ, Nam KH, Chung WY (2019) Impact of body mass index on robotic transaxillary thyroidectomy. Sci Rep 9(1):8955

    Article  PubMed  PubMed Central  Google Scholar 

  36. Stevenson CE, Gardner DF, Grover AC (2012) Patient factors affecting operative times for single-incision trans-axillary robotic-assisted (STAR) thyroid lobectomy: does size matter? Ann Surg Oncol 19(5):1460–1465

    Article  PubMed  Google Scholar 

  37. Steurer M, Passler C, Denk DM, Schneider B, Niederle B, Bigenzahn W (2002) Advantages of recurrent laryngeal nerve identification in thyroidectomy and parathyroidectomy and the importance of preoperative and postoperative laryngoscopic examination in more than 1000 nerves at risk. Laryngosc 112(1):124–133

    Article  Google Scholar 

  38. Jeannon JP, Orabi AA, Bruch GA, Abdalsalam HA, Simo R (2009) Diagnosis of recurrent laryngeal nerve palsy after thyroidectomy: a systematic review. Int J Clin Practic 63(4):624–629

    Article  Google Scholar 

  39. Lo CY, Kwok KF, Yuen PW (2000) A prospective evaluation of recurrent laryngeal nerve paralysis during thyroidectomy. Arch Surg (Chicago, IL: 1960) 135(2):204–207

  40. Hayward NJ, Grodski S, Yeung M, Johnson WR, Serpell J (2013) Recurrent laryngeal nerve injury in thyroid surgery: a review. ANZ J Surg 83(1–2):15–21

    Article  PubMed  Google Scholar 

  41. Merchavy S, Marom T, Forest VI, Hier M, Mlynarek A, McHugh T, Payne R (2015) Comparison of the incidence of postoperative hypocalcemia following total thyroidectomy vs completion thyroidectomy. Otolaryngol Head Neck Surg 152(1):53–56

    Article  PubMed  Google Scholar 

  42. Bergenfelz A, Jansson S, Kristoffersson A, Mårtensson H, Reihnér E, Wallin G, Lausen I (2008) Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patients. Langenbeck’s Arch Surg 393(5):667–673

    Article  CAS  Google Scholar 

  43. Hundahl SA, Cady B, Cunningham MP, Mazzaferri E, McKee RF, Rosai J, Shah JP, Fremgen AM, Stewart AK, Hölzer S, US and German Thyroid Cancer Study Group (2000) Initial results from a prospective cohort study of 5583 cases of thyroid carcinoma treated in the united states during 1996. U.S. and German Thyroid Cancer Study Group. An American College of Surgeons Commission on Cancer Patient Care Evaluation study. Cancer 89(1):202–217

  44. Jensen PV, Jelstrup SM, Homøe P (2015) Long-term outcomes after total thyroidectomy. Dan Med J 62(11):A5156

  45. Rocke DJ, Mulder H, Cyr D, Kahmke R, Lee WT, Puscas L, Schulz K, Witsell DL (2020) The effect of lateral neck dissection on complication rate for total thyroidectomy. Am J Otolaryngol 41(3):102421

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

The authors wish to acknowledge the financial support of the Catholic Medical Center Research Foundation made in the program year of 2022.

Funding

The authors declare that no funds, grants, or other support were received during the preparation of this manuscript.

Author information

Authors and Affiliations

Authors

Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by SA and KSK The first draft of the manuscript was written by SA and all authors commented on previous versions of the manuscript and approved the final manuscript.

Corresponding author

Correspondence to Kwangsoon Kim.

Ethics declarations

Conflict of interests

The authors have no relevant financial or non-financial interests to disclose.

Ethics approval

This study was conducted in accordance with the Declaration of Helsinki and approved by the Institutional Review Board of Seoul St. Mary’s Hospital, the Catholic University of Korea (approval No.: KC23RASI0236, Date: April 21, 2023).

Consent to participate & consent to publish

This study waived the requirement for informed consent due to the retrospective nature of the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

An, S., Park, J., Kim, K. et al. Safety and surgical outcomes of single-port trans-axillary robot-assisted thyroidectomy: Experience from a consecutive series of 300 patients. J Robotic Surg 18, 13 (2024). https://doi.org/10.1007/s11701-023-01810-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s11701-023-01810-9

Keywords

Navigation