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Transplantationsmöglichkeiten für Patienten mit Diabetes und fortgeschrittener Niereninsuffizienz

Transplantation options for patients with diabetes and advanced kidney disease

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Die Diabetologie Aims and scope

Zusammenfassung

Die simultane Pankreas- und Nierentransplantation (SPK) ist eine mögliche Therapieoption für Menschen mit Diabetes mellitus Typ 1 und präterminaler Niereninsuffizienz. Trotz der Entwicklungen in den Operationstechniken und der Nachsorge wird sie bei ausreichendem Organangebot immer weniger durchgeführt, obwohl ihre Überlegenheit auch gegenüber der Lebendnierenspende wissenschaftlich gut belegt ist. Die guten Ergebnisse, die kurzen Wartezeiten und die Möglichkeit der Aufnahme in die Warteliste vor Eintritt der Dialysepflichtigkeit sollten bei den Aufklärungsgesprächen mit den Erkrankten immer berücksichtigt werden.

Abstract

Although simultaneous pancreas–kidney transplantation (SPK) is an effective treatment option for patients with type 1 diabetes mellitus and advanced chronic kidney disease, it is not offered and conducted as widely as would have been expected. At least in Europe, the numbers are stagnating or continuously decreasing. This is the case despite the excellent long-term outcome—even compared to living kidney donation—and the lack of organ shortage. The favorable results, the short waiting list time, and the feasibility of pre-emptive listing should encourage physicians to offer this treatment modality to patients with type 1 diabetes mellitus.

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  1. Klinik für Nieren- und Hochdruckkrankheiten, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland

    Christos Chatzikyrkou

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Correspondence to Christos Chatzikyrkou.

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Chatzikyrkou, C. Transplantationsmöglichkeiten für Patienten mit Diabetes und fortgeschrittener Niereninsuffizienz. Diabetologie 19, 281–287 (2023). https://doi.org/10.1007/s11428-022-00995-1

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