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Effect of sinus opacification on the severity of obstructive sleep apnea

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Abstract

Purpose

The association between rhinosinusitis and obstructive sleep apnea (OSA) remains unclear. Here, we aimed to elucidate the association between sinus opacification and OSA severity.

Methods

Patients with snoring problems who visited our clinic from April 2018 to December 2020 were retrospectively enrolled. Among these patients, we included those who underwent a physical examination, overnight polysomnography, and osteomeatal-unit computed tomography. We evaluated the association between apnea–hypopnea index (AHI) and Lund-Mackay score (LMS). LMS ≥ 5 was considered indicative of sinus opacification.

Results

Among the 122 patients included in the study, LMS exhibited an increasing trend based on OSA severity. The LMS in the moderate OSA group was significantly higher than that in the no OSA group (P = 0.002), and the LMS in the severe OSA group was significantly higher than that in the no OSA (P < 0.001) and mild OSA (P = 0.006) groups. A correlation analysis revealed that AHI was significantly associated with body mass index (BMI) (r = 0.367, P < 0.001) and LMS (r = 0.255, P = 0.005). A multivariate analysis revealed that sinus opacification was associated with moderate and severe OSA [Adjusted odds ratio = 11.986 (P = 0.005) and 3.756 (P = 0.044), respectively] after adjusting for age, sex, BMI, smoking, hypertension, atopy, tonsil size, and palatal position. The effect of sinus opacification on OSA severity was comparable to that of overweight.

Conclusion

Sinus opacification may increase OSA severity since moderate and severe OSA is independently associated with it.

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Data availability

The data that support the findings of this study are available from Kangwon National University Hospital Sleep Center, but restrictions apply to the availability of these data, which were used under license for the current study; therefore, they are not publicly available. However, data are available from the authors upon reasonable request and with the permission of Kangwon National University Hospital Sleep Center.

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Funding

This research was supported by Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education (2019R1F1A1051106).

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Authors and Affiliations

  1. Department of Otolaryngology, Kangwon National University Hospital, 156, Baengnyeong-ro, Chuncheon-Si, Gangwon-Do, 24289, Republic of Korea

    Jun Yeon Won, Eui-Cheol Nam & Woo Hyun Lee

  2. Department of Otolaryngology, Kangwon National University, Chuncheon, Korea

    Jun Yeon Won, Eui-Cheol Nam & Woo Hyun Lee

  3. Department of Otolaryngology, National Police Hospital, Seoul, Korea

    Taehun Lim & Joon Bum Joo

  4. Department of Otorhinolaryngology, Seoul National University College of Medicine, Boramae Medical Center, Seoul, Korea

    Seung-No Hong

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  1. Jun Yeon Won
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Contributions

W.H.L. designed the study. W.H.L. and J.Y.W. wrote the main manuscript text. E.N., T.L, and J.B.J. collected the data and reviewed the manuscript. S.H. analyzed the data.

Corresponding author

Correspondence to Woo Hyun Lee.

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Ethics approval

The ethics committee of the Kangwon National University Hospital (IRB NO. KNUH-A-2019–10-003–005) approved the use of these data. Written informed consent was exempted by the Institutional Review Board.

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The authors declare no competing interests.

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Won, J.Y., Nam, EC., Lim, T. et al. Effect of sinus opacification on the severity of obstructive sleep apnea . Sleep Breath 26, 847–853 (2022). https://doi.org/10.1007/s11325-021-02431-y

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  • DOI: https://doi.org/10.1007/s11325-021-02431-y

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