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Optimization of the Manufacturing Technology for Promedone. Synthesis of 1,2,5-trimethylpiperidin-4-one

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Pharmaceutical Chemistry Journal Aims and scope

A simple and technologically convenient method for the preparation of 1,2,5-trimethylpiperidin-4-one, a key compound in the synthesis of the drug Promedol, was developed.

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Authors and Affiliations

  1. State Science Research Institute Organic Chemistry and Technology, Moscow, Russia

    O. I. Lukashov, P. V. Kazakov & N. S. Mirzabekova

Authors
  1. O. I. Lukashov
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  2. P. V. Kazakov
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  3. N. S. Mirzabekova
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Corresponding author

Correspondence to O. I. Lukashov.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 49, No. 1, pp. 39 – 41, January, 2015.

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Lukashov, O.I., Kazakov, P.V. & Mirzabekova, N.S. Optimization of the Manufacturing Technology for Promedone. Synthesis of 1,2,5-trimethylpiperidin-4-one. Pharm Chem J 49, 51–54 (2015). https://doi.org/10.1007/s11094-015-1220-1

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  • DOI: https://doi.org/10.1007/s11094-015-1220-1

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