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Social Anhedonia: (f)MRI Studies

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Anhedonia, particularly social anhedonia, is an important psychopathological symptom which plays a key role in the development of depression and schizophrenia. In healthy people, the level of social anhedonia is associated with changes in the structure, activation, and the functional connections of different parts of the prefrontal cortex, temporal, and temporal-parietal areas, along with the basal ganglia. Key fMRI correlates of social anhedonia in patients with schizophrenia are located in the temporal lobe. There are insufficient results from people with depression and other mental disorders to allow generalization. In contrast to physical anhedonia, social anhedonia does not show a specific association with the volume or activation of the nucleus accumbens.

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Translated from Uspekhi Fiziologicheskikh Nauk, Vol. 54, No. 1, pp. 70–90, January–March, 2023

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Melnikov, M.E. Social Anhedonia: (f)MRI Studies. Neurosci Behav Physi 53, 1084–1100 (2023). https://doi.org/10.1007/s11055-023-01502-9

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