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High-Definition Transcranial Direct Current Electrical Stimulation

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Transcranial direct current electrical stimulation (tDCS) is an intensely developing area in noninvasive neuromodulation. Despite large numbers of published studies, data on the possible clinical applications of the method are contradictory. One limitation of tDCS is the relatively non-local nature of stimulation using the standard montage. High-definition tDCS (HD-tDCS) is a modification of the method in which small ring electrodes are used and has greater stimulation focality. In the most commonly used montage, 4 × 1 HD-tDCS, a ring electrode (anode or cathode) is positioned over the target area and is surrounded by reference electrodes of the opposite polarity. This article addresses current data on the methodology, physiological aspects, clinical efficacy, safety, and tolerance of HD-tDCS.

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Authors and Affiliations

  1. Neurology Research Center, Moscow, Russia

    A. G. Poydasheva, I. S. Bakulin, D. Yu. Lagoda, N. A. Suponeva & M. A. Piradov

  2. Department of Rehabilitation Medicine, Karolinska Institute, Danderyd University Hospital, Stockholm, Sweden

    E. L. Pavlova

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  1. A. G. Poydasheva
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  6. M. A. Piradov
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Correspondence to A. G. Poydasheva.

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Translated from Uspekhi Fiziologicheskikh Nauk, Vol. 52, No. 1, pp. 3–15, January–March, 2021.

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Poydasheva, A.G., Bakulin, I.S., Lagoda, D.Y. et al. High-Definition Transcranial Direct Current Electrical Stimulation. Neurosci Behav Physi 51, 1190–1198 (2021). https://doi.org/10.1007/s11055-021-01178-z

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  • DOI: https://doi.org/10.1007/s11055-021-01178-z

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