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Hemizygous BTK Gene Variant Causing X-Linked Agammaglobulinemia in Two Siblings

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Fig. 1

Data Availability

All data generated or analyzed during this study are included in this article.

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Funding

The authors extend their appreciation to the Deanship of Scientific Research, king Saud University for funding through Vice Deanship of Scientific Research Chairs; Research Chair of Prince Abdullah Ben Khalid Celiac Disease research chair; Riyadh, Kingdom of Saudi Arabia.

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Authors and Affiliations

  1. Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates

    Narjes Saheb Sharif-Askari, Shirin Hafezi, Fatemeh Saheb Sharif-Askari & Rabih Halwani

  2. Department of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates

    Narjes Saheb Sharif-Askari & Rabih Halwani

  3. Department of Pharmacy Practice and Pharmacotherapeutics, College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates

    Fatemeh Saheb Sharif-Askari

  4. Department of Health Sciences and Technology, ETH Zurich, 8092, Zurich, Switzerland

    Naomi Frommenwiler

  5. Prince Abdullah Bin Khaled Celiac Disease Research Chair, Department of Pediatrics, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia

    Rabih Halwani

Authors
  1. Narjes Saheb Sharif-Askari
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  2. Shirin Hafezi
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  3. Fatemeh Saheb Sharif-Askari
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  4. Naomi Frommenwiler
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  5. Rabih Halwani
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Contributions

Rabih Halwani, Narjes Saheb Sharif-Askari, and Fatemeh Saheb Sharif-Askari conceived and designed the experiments. Narjes Saheb Sharif-Askari performed sample and data collection. Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Shirin Hafezi, and Naomi Frommenwiler performed the experiments. Rabih Halwani, Narjes Saheb Sharif-Askari, and Fatemeh Saheb Sharif-Askari analyzed and interpreted the data. All authors contributed to the writing and revision of the manuscript.

Corresponding author

Correspondence to Rabih Halwani.

Ethics declarations

Ethical Approval

Approval was obtained from the ethics committee of the University of Sharjah. The procedures used in this study adhere to the principles of the Declaration of Helsinki.

Consent to Participate

Informed consent was obtained from all individual participants or their parents included in the study.

Consent for Publication

This is not applicable.

Conflict of Interest

The authors declare no competing interests.

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Saheb Sharif-Askari, N., Hafezi, S., Saheb Sharif-Askari, F. et al. Hemizygous BTK Gene Variant Causing X-Linked Agammaglobulinemia in Two Siblings. J Clin Immunol 43, 1533–1536 (2023). https://doi.org/10.1007/s10875-023-01534-3

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  • DOI: https://doi.org/10.1007/s10875-023-01534-3

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