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Optical coherence tomography angiography changes in macula-off rhegmatogenous retinal detachments repaired with silicone oil

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Abstract

Purpose

To evaluate the changes on optical coherence tomography angiography (OCTA) in macula-off rhegmatogenous retinal detachments (RRD) treated with pars plana vitrectomy (PPV) and silicone oil (SO) 5000-cSt tamponade.

Materials and method

Forty-five eyes with macula-off RRD treated with PPV and SO tamponade were enrolled with the fellow eye being used as a control. OCT-A was obtained using the RTVue XR 100 Avanti (Optovue, Inc., Fremont, CA, USA) at the 1-week, 1-month, and 3-month postoperative visit. Retinal vascular density, choroidal flow area, retinal thickness, and foveal avascular zone area were evaluated at each follow-up visit. Changes in these parameters in the postoperative eye were tracked at each follow-up visit as were the relative differences between the postoperative eye and the contralateral eye.

Results

Vascular density of parafoveal superficial capillary plexus and total retina demonstrated significant decrease in the postoperative silicone-filled eye when compared to the fellow eye (P < 0.0001). Although there was some improvement in these values at subsequent follow-ups, they remained less than the fellow eye. Foveal (P = 0.002) and parafoveal (P < 0.0001) thickness were less than the fellow eye. Choroidal flow area did not show a significant change in operated eye compared with the fellow eye.

Conclusion

Eyes with macula-off RRD repaired with PPV and SO, at 3-month follow-up, demonstrated less retinal vascular density at parafoveal area as well as lower retinal thickness at fovea when compared to the healthy fellow eyes.

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Abbreviations

OCTA:

Optical coherence tomography angiography

RRD:

Rhegmatogenous retinal detachments

PPV:

Pars plana vitrectomy

SO:

Silicone oil

IOP:

Intraocular pressure

OCT:

Optical coherence tomography

FAZ:

Foveal avascular zone

IRB:

Institutional review board

SCP:

Superficial capillary plexus

DCP:

Deep capillary plexus

ILM:

Internal limiting membrane

IPL:

Inner plexiform layer

ETDRS:

Early treatment diabetic retinopathy study

LMM:

Linear mixed model

OPL:

Outer plexiform layer

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Authors and Affiliations

  1. Retina Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran

    Ramak Roohipoor, Fereshteh Tayebi, Hamid Riazi-Esfahani, Alireza Khodabandeh, Reza Karkhaneh, Bita Momenaei & Nazanin Ebrahimiadib

  2. Department of Ophthalmology, University of Florida, Gainesville, FL, USA

    Ramak Roohipoor, Samaneh Davoudi & Girban S. Khurshid

  3. Eye Monitoring Center, Kaiser Permanente Southern California, 1011 Baldwin Park Blvd, Baldwin Park, CA, 91706, USA

    Bobeck S. Modjtahedi

Authors
  1. Ramak Roohipoor
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  2. Fereshteh Tayebi
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  3. Hamid Riazi-Esfahani
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  4. Alireza Khodabandeh
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  8. Bita Momenaei
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  9. Nazanin Ebrahimiadib
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  10. Bobeck S. Modjtahedi
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Contributions

Conceived and performed experiments: F.T, wrote the manuscript: N.E and H.R.E, conceptualization: R.R, perform experiments: B.M. Revising manuscript: B.S.M and A.K, Review: S.D and G.K, Supervision: R.K.

Corresponding author

Correspondence to Nazanin Ebrahimiadib.

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No conflicting relationship exists for any author.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Roohipoor, R., Tayebi, F., Riazi-Esfahani, H. et al. Optical coherence tomography angiography changes in macula-off rhegmatogenous retinal detachments repaired with silicone oil. Int Ophthalmol 40, 3295–3302 (2020). https://doi.org/10.1007/s10792-020-01516-z

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  • DOI: https://doi.org/10.1007/s10792-020-01516-z

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