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A study of dry eye after cataract surgery in MGD patients

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Abstract

Objective

To investigate the dry eye symptoms after cataract surgery in MGD patients and their relationships

Methods

The study included 115 patients (115 eyes) with age-related cataract that underwent uncomplicated cataract surgery, and the patients were divided into two groups according to the MGD diagnostic criteria: group A (MGD group) and group B (control group). Schirmer I test (ST-I), tear breakup time (TBUT), and corneal fluorescein staining (CFS) were performed preoperatively and at 3 days, 7 days, 14 days, and 30 days postoperatively. We also measured eyelid meibomian gland morphology, meibomian gland expression, and meibum character scores before and after the cataract surgery.

Results

Postoperatively, in group A, TBUT decreased and CFS scores increased significantly. ST-I increased in the early postoperative course but decreased later. The eyelid margin morphology scores and meibomian gland expression scores of group A significantly increased after the cataract operation. Thus, patients with MGD may have a greater chance of developing the dry eye disease after cataract surgery. Cataract surgery may aggravate the signs of MGD, and the severity of MGD may positively correlate with TBUT, CFS, and corneal lesions after surgery.

Conclusions

The characteristics of dry eye after cataract surgery in patients with MGD are different from common cataract patients, changes in the early postoperative phase to the ocular surface were caused by surgical factors, and the damages to epithelial function in the later postoperative phase were mainly associated with the inflammation of the meibomian gland and eyelid.

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Funding

This work was supported by the Department of Educational Program of Jiangxi Province, China [No. 201760183].

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Author notes

  1. Jing-Jing Qiu and Tao Sun have contributed equally to this study.

Authors and Affiliations

  1. Department of Ophthalmology, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi Province, China

    Jing-Jing Qiu, Shu-Hua Fu, Yi-Feng Yu, Zhi-Peng You, Qian Zhang, Fei Liu, Jun-Qi Huang & Zhi-Hong Wang

  2. Department of Cornea, The Affiliated Eye Hospital of Nanchang University, No. 463 of Bayi Road, Donghu District, Nanchang, 330006, Jiangxi Province, China

    Tao Sun

Authors
  1. Jing-Jing Qiu
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  2. Tao Sun
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  3. Shu-Hua Fu
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  4. Yi-Feng Yu
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  5. Zhi-Peng You
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  6. Qian Zhang
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  7. Fei Liu
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  8. Jun-Qi Huang
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Contributions

JJQ and TS designed the study. SHF, ZHW, and JQH carried out the examination. FL, QZ, and YFY did the interpretation of the data. ZPY edited the language of the manuscript. TS and JJQ wrote the manuscript.

Corresponding author

Correspondence to Tao Sun.

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Conflict of interest

The authors declare that they have no competing interests.

Ethical approval

This study has been approved by the Ethics Committee of the Second Affiliated Hospital of Nanchang University.

Informed consent

All participants provided informed written consent that was endorsed by the Second Affiliated Hospital of Nanchang University.

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Qiu, JJ., Sun, T., Fu, SH. et al. A study of dry eye after cataract surgery in MGD patients. Int Ophthalmol 40, 1277–1284 (2020). https://doi.org/10.1007/s10792-020-01294-8

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  • DOI: https://doi.org/10.1007/s10792-020-01294-8

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