Two new phloroglucinol derivatives were isolated from the leaves of Syzygium fluviatile. The structures were elucidated as (Z,Z,Z)-1-(2,4-dihydroxy-6-methoxyphenyl)-octadeca-9,12,15-trien-1-one (1) and (Z,Z)-1-(5-methyl-2,4-dihydroxy-6-methoxyphenyl)-octadeca-9,12-dien-1-one (2) by means of extensive spectroscopic analyses including HR-ESI-MS and NMR spectra. Among them, compound 1 exhibited significant inhibitory activity against α-glucosidase with an IC50 value of 3.63 μM.
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The work was supported financially by the National Natural Science Founding of China (31560098).
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Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2023, pp. 716–718
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Zhang, DL., Hu, YK., He, YB. et al. Two New Phloroglucinol Derivatives from Syzygium fluviatile. Chem Nat Compd 59, 848–851 (2023). https://doi.org/10.1007/s10600-023-04132-2
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DOI: https://doi.org/10.1007/s10600-023-04132-2