The ethanolic extract derived from the whole plant of Pardoglossum cheirifolium was submitted to phytochemical investigation. A new pyrrolizidine alkaloid, 3′-O-acetylleptanthine N-oxide (1), was isolated together with three known compounds of the same class, i.e., heliosupine N-oxide (2), heliosupine (3), and heliovicine (4). The structure of the new compound was elucidated after extensive mono- and bidimensional NMR experiments and confirmed by a MS experiment.
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Acknowledgment
The authors would like to thank the University of Oran1 (Project PRFU No. D01N01UN310120190003), LRZA, DGRSDT, Algeria.
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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2021, pp. 424–426.
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Benamar, H., Tomassini, L., Frezza, C. et al. Pyrrolizidine Alkaloids from Pardoglossum cheirifolium. Chem Nat Compd 57, 497–499 (2021). https://doi.org/10.1007/s10600-021-03395-x
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DOI: https://doi.org/10.1007/s10600-021-03395-x