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Lungenmetastasen – Onkologische Bedeutung und Therapie

Lung metastases—oncological significance and treatment

  • Leitthema
  • Published:
Zeitschrift für Pneumologie Aims and scope

Zusammenfassung

Hintergrund

Die Lunge ist ein häufiger Ort der Metastasierung bei einer Vielzahl unterschiedlicher Tumorerkrankungen.

Fragestellung

Darstellung der Inzidenz, Diagnostik, Therapie und Prognose von Lungenmetastasen.

Material und Methode

Sichtung der relevanten Literatur über öffentlich zugängliche Datenbanken (u. a. PubMed, Embase) und Bewertung im multidisziplinären Expertenkreis

Ergebnisse

Die Lungenmetastasierung bedarf einer differenzierten und spezialisierten radiologischen und histopathologischen Bewertung. Es stehen zahlreiche wirksame lokal-ablative und systemische Behandlungsverfahren zur Verfügung.

Schlussfolgerung

Der Beitrag gibt eine multidisziplinäre ausgerichtete Übersicht über Diagnose- und Therapieoptionen bei Lungenmetastasen

Abstract

Background

The lung is a common site of metastasis in numerous cancers.

Objective

To present the incidence, diagnosis, treatment, and prognosis of pulmonary metastases.

Materials and methods

Review of relevant literature via publicly available databases (including PubMed and Embase) and evaluation in a multidisciplinary expert panel.

Results

Pulmonary metastasis requires differential and specialized radiologic and histopathologic evaluation. Numerous effective local ablative and systemic treatment modalities are available.

Conclusion

This article provides a multidisciplinary focused review of diagnostic and treatment options for pulmonary metastases.

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Author information

Authors and Affiliations

  1. Klinik und Poliklinik für Viszeral‑, Transplantations‑, Thorax- und Gefäßchirurgie, Universitäres Krebszentrum Leipzig (UCCL) im Mitteldeutschen Krebszentrum/Comprehensive Cancer Center Central Germany (CCCG), Universitätsmedizin Leipzig, Leipzig, Deutschland

    Sebastian Krämer

  2. Institut für Pathologie, Universitäres Krebszentrum Leipzig (UCCL) im Mitteldeutschen Krebszentrum/Comprehensive Cancer Center Central Germany (CCCG), Universitätsmedizin Leipzig, Leipzig, Deutschland

    Hendrik Bläker & Maximilian von Laffert

  3. Klinik und Poliklinik für Diagnostische und Interventionelle Radiologie, Universitäres Krebszentrum Leipzig (UCCL) im Mitteldeutschen Krebszentrum/Comprehensive Cancer Center Central Germany (CCCG), Universitätsmedizin Leipzig, Leipzig, Deutschland

    Timm Denecke

  4. Klinik und Poliklinik für Strahlentherapie, Universitäres Krebszentrum Leipzig (UCCL) im Mitteldeutschen Krebszentrum/Comprehensive Cancer Center Central Germany (CCCG), Universitätsmedizin Leipzig, Leipzig, Deutschland

    Nils Nicolay

  5. Klinik und Poliklinik für Onkologie, Gastroenterologie, Hepatologie, Pneumologie, Infektiologie, Universitäres Krebszentrum Leipzig (UCCL) im Mitteldeutschen Krebszentrum/Comprehensive Cancer Center Central Germany (CCCG), Universitätsmedizin Leipzig, Liebigstr. 22, 04103, Leipzig, Deutschland

    Florian Lordick

Authors
  1. Sebastian Krämer
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  2. Hendrik Bläker
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  3. Timm Denecke
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  4. Nils Nicolay
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  5. Maximilian von Laffert
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  6. Florian Lordick
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Corresponding author

Correspondence to Florian Lordick.

Ethics declarations

Interessenkonflikt

F. Lordick berichtet Vortragshonorare von Art Tempi, AstraZeneca, Servier, Bristol-Myers Squibb, Daaichi Sankyo, Eli Lilly, Falk Foundation, Incyte, Medscape, Merck KGaA, Merck Sharp & Dohme, Novartis, Roche, Servier und StreamedUp; Beraterhonorare von Amgen, Astellas Pharma, Biontech, Bristol-Myers Squibb, Merck Sharp and Dohme; institutionelle Forschungsunterstützung durch AstraZeneca, Bristol-Myers Squibb, Gilead und Iomedico. S. Krämer, H. Bläker, T. Denecke, N. Nicolay und M. von Laffert geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autor/-innen keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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Krämer, S., Bläker, H., Denecke, T. et al. Lungenmetastasen – Onkologische Bedeutung und Therapie. Z Pneumologie 20, 273–283 (2023). https://doi.org/10.1007/s10405-023-00520-1

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  • DOI: https://doi.org/10.1007/s10405-023-00520-1

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