Skip to main content

Advertisement

SpringerLink
Log in

Effect of photobiomodulation therapies on the root resorption associated with orthodontic forces: a pilot study using micro computed tomography

  • Original Article
  • Published:
Clinical Oral Investigations Aims and scope Submit manuscript

Abstract

Objectives

The aim of this study is to investigate the effect of photobiomodulation therapies on root resorption compared with the placebo group.

Materials and methods

Thirty patients who were admitted to the Gaziantep University Faculty of Dentistry Orthodontics Department for treatment, with an indication of upper right first premolar tooth extraction were included. Before the individuals’ orthodontic treatment, 0.022 slot MBT brackets and tubes were placed on the maxillary first premolar and molar. A 150-g buccal tipping force was applied to the first premolar. Cantilever spring with 0.017 × 0.025 Beta Titanium wire was used for force application. Individuals were then randomly divided into three groups. For the first group, laser application was performed with an 810-nm GaAlAs laser device at 0, 3, 7, 14, 21, and 28 days to 8 J/cm2. For the second group, an LED application according to the manufacturer’s instructions with an 850-nm wavelength and 20 mW/cm2 output power for 10 min per day during the experiment. For the third group, a placebo therapy was completed whereby a laser device that did not make active pulses was used. At the end of 4 weeks, the amount of root surface resorption was compared using micro-CT imaging after the extraction of the teeth.

Results

No significant difference was found between the groups in terms of regional and total crater volumes. It was observed that photobiomodulation therapies were not different from the control group in terms of forming root resorption.

Conclusions

It is seen that laser and LED photobiomodulation therapies used for accelerate orthodontic tooth movement do not differ from the control group in terms of forming root resorption.

Clinical relevance

According to the results of this pilot study on this subject, which needs to be clarified with new findings in the future, LED and laser applications may not increase the risk for root resorption.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Yamasaki K, Shibata Y, Imai S, Tani Y, Shibasaki Y, Fukuhara T (1984) Clinical application of prostaglandin E1 (PGE1) upon orthodontic tooth movement. Am J Orthod Dentofac Orthoped 85(6):508–518

    Article  Google Scholar 

  2. Long H, Pyakurel U, Wang Y, Liao L, Zhou Y, Lai W (2012) Interventions for accelerating orthodontic tooth movement: a systematic review. Angle Orthod 83(1):164–171

    Article  Google Scholar 

  3. Genc G, Kocadereli I, Tasar F, Kilinc K, El S, Sarkarati B (2013) Effect of low-level laser therapy (LLLT) on orthodontic tooth movement. Lasers Med Sci 28(1):41–47

    Article  Google Scholar 

  4. Nimeri G, Kau CH, Corona R, Shelly J (2014) The effect of photobiomodulation on root resorption during orthodontic treatment. Clin Cosmet Invest Dent 6(1):1–8

    Google Scholar 

  5. Brezniak N, Wasserstein A (2002) Orthodontically induced inflammatory root resorption. Part I: the basic science aspects. Angle Orthod 72(2):175–179

    PubMed  Google Scholar 

  6. Krishnan V (2005) Critical issues concerning root resorption: a contemporary review. World J Orthod 6(1):30–40

    PubMed  Google Scholar 

  7. Chan E, Dalci O, Petocz P, Papadopoulou AK, Darendeliler MA (2018) (2018) physical properties of root cementum: part 26. Effects of micro-osteoperforations on orthodontic root resorption: a microcomputed tomography study. Am J Orthod Dentofac Orthoped 153(2):204–213

    Article  Google Scholar 

  8. Altan AB, Bicakci AA, Mutaf HI, Ozkut M, Inan VS (2015) The effects of low-level laser therapy on orthodontically induced root resorption. Lasers Med Sci 30(8):2067–2076

    Article  Google Scholar 

  9. Suzuki SS, Garcez AS, Suzuki H, Ervolino E, Moon W, Ribeiro MS (2016) Low-level laser therapy stimulates bone metabolism and inhibits root resorption during tooth movement in a rodent model. J Biophotonics 9(11–12):1222–1235

    Article  Google Scholar 

  10. Vasconcelos EC, Henriques JFC, Sousa MVS, de Oliveira RC, Consolaro A, Pinzan A, Henriques FP, Bronfman CN (2016) Low-level laser action on orthodontically induced root resorption: histological and histomorphometric evaluation. J Lasers Med Sci 7(3):146–151

    Article  Google Scholar 

  11. Yeh NG, Wu C-H, Cheng TC (2010) Light-emitting diodes—their potential in biomedical applications. Renew Sust Energ Rev 14(8):2161–2166

    Article  Google Scholar 

  12. Ekizer A, Uysal T, Guray E, Akkus D (2015) Effect of LED-mediated-photobiomodulation therapy on orthodontic tooth movement and root resorption in rats. Lasers Med Sci 30(2):779–785

    Article  Google Scholar 

  13. Fonseca P, Lima F, Higashi D, Koyama D, Filho OTD, Dias I, Ramos PS (2013) Effects of light emitting diode (LED) therapy at 940 nm on inflammatory root resorption in rats. Lasers Med Sci 28(1):49–55

    Article  Google Scholar 

  14. Higashi DT, Andrello AC, Tondelli PM, de Oliveira Toginho Filho D, de Paula RS (2017) Three consecutive days of application of LED therapy is necessary to inhibit experimentally induced root resorption in rats: a microtomographic study. Lasers Med Sci 32(1):181–187

    Article  Google Scholar 

  15. Huang TTY, Elekdag-Turk S, Dalci O, Almuzian M, Karadeniz EI, Gonzales C, Petocz P, Turk T, Darendeliler MA (2017) The extent of root resorption and tooth movement following the application of ascending and descending magnetic forces: a prospective split mouth, microcomputed-tomography study. Eur J Orthod 39(5):547–553

    Article  Google Scholar 

  16. Patterson BM, Dalci O, Papadopoulou AK, Madukuri S, Mahon J, Petocz P, Spahr A, Darendeliler MA (2017) Effect of piezocision on root resorption associated with orthodontic force: a microcomputed tomography study. Am J Orthod Dentofac Orthoped 151(1):53–62

    Article  Google Scholar 

  17. Malek S, Darendeliler MA, Swain MV (2001) Physical properties of root cementum: part I. A new method for 3-dimensional evaluation. Am J Orthod Dentofac Orthoped 120(2):198–208

    Article  Google Scholar 

  18. Malek S, Darendeliler MA, Rex T, Kharbanda OM, Srivicharnkul P, Swain MV, Petocz P (2003) Physical properties of root cementum: part 2. Effect of different storage methods. Am J Orthod Dentofac Orthoped 124(5):561–570

    Article  Google Scholar 

  19. Chan EKM, Darendeliler MA (2004) Exploring the third dimension in root resorption. Orthod Craniofac Res 7(2):64–70

    Article  Google Scholar 

  20. Ho C, Turk T, Elekdag-Turk S, Jones AS, Petocz P, Cheng LL, Darendeliler MA (2011) Physical properties of root cementum: part 19. Comparison of the amounts of root resorption between the right and left first premolars after application of buccally directed heavy orthodontic tipping forces. Am J Orthod Dentofac Orthoped 140(1):e49–e52

    Article  Google Scholar 

  21. AlSayed Hasan MMA, Sultan K, Hamadah O (2017) Evaluating low-level laser therapy effect on reducing orthodontic pain using two laser energy values: a split-mouth randomized placebo-controlled trial. Eur J Orthod 40(1):23–28

    Article  Google Scholar 

  22. Limpanichkul W, Godfrey K, Srisuk N, Rattanayatikul C (2006) Effects of low-level laser therapy on the rate of orthodontic tooth movement. Orthod Craniofac Res 9(1):38–43

    Article  Google Scholar 

  23. Luger EJ, Rochkind S, Wollman Y, Kogan G, Dekel S (1998) Effect of low-power laser irradiation on the mechanical properties of bone fracture healing in rats. Lasers Surg Med 22(2):97–102

    Article  Google Scholar 

  24. Ueda Y, Shimizu N (2001) Pulse irradiation of low-power laser stimulates bone nodule formation. J Oral Sci 43(1):55–60

    Article  Google Scholar 

  25. Karu TI, Pyatibrat LV, Kolyakov SF, Afanasyeva NI (2005) Absorption measurements of a cell monolayer relevant to phototherapy: reduction of cytochrome c oxidase under near IR radiation. J Photochem Photobiol B Biol 81(2):98–106

    Article  Google Scholar 

  26. Cheng LL, Turk T, Elekdag-Turk S, Jones AS, Petocz P, Darendeliler MA (2009) Physical properties of root cementum: part 13. Repair of root resorption 4 and 8 weeks after the application of continuous light and heavy forces for 4 weeks: a microcomputed-tomography study. Am J Orthod Dentofacial Orthop 136(3):320.e1–320.10

    Google Scholar 

  27. Chan E, Darendeliler MA (2005) Physical properties of root cementum: part 5. Volumetric analysis of root resorption craters after application of light and heavy orthodontic forces. Am J Orthod Dentofac Orthop 127(2):186–195

    Article  Google Scholar 

Download references

Funding

The work was supported by the Coordinatorship of Scientific Research Projects, University of Gaziantep.

Author information

Authors and Affiliations

  1. Dentistry Faculty, Department of Orthodontics, Gaziantep University, 27300 Şehitkamil, Gaziantep, Turkey

    Merve Goymen & Aysegul Gulec

Authors
  1. Merve Goymen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Aysegul Gulec
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Merve Goymen.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from participants included in the study.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Goymen, M., Gulec, A. Effect of photobiomodulation therapies on the root resorption associated with orthodontic forces: a pilot study using micro computed tomography. Clin Oral Invest 24, 1431–1438 (2020). https://doi.org/10.1007/s00784-019-03155-w

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00784-019-03155-w

Keywords

Search

Navigation